Clinical trials: SARS CoV-2 Infection
Mild-to-Moderate COVID-19
A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function
This exploratory, open-label clinical study aims to explore the physiologic effects of KB109, a novel glycan, on adult patients with COVID-19 illness on gut microbiota structure and function in the outpatient setting.
- Trial name
- NCT04486482
- Testing
- KB109 + Self Supportive Care (SSC), Self Supportive Care (SSC) Alone
- Where
- 12 sites in United States
- Volunteers
- 49 people
- Sponsor
- Kaleido Biosciences
Post COVID-19 Cognitive Impairment
A Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment
Some people who have been infected with the virus that causes COVID-19 can experience long-term effects from their infection, known as post COVID-19 conditions (PCC) or long COVID1.
- Trial name
- NCT05857124
- Testing
- Vielight Neuro RX Gamma active device
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vielight Inc.
Covid19, Paludism
Malaria as a Protection Factor Against Severe COVID-19 (Known as SARS-COV-2) in the Democratic Republic of Congo (Palu-COVID)
In this study, the investigators will explore the reasons for the apparently lower proportion of severe COVID-19 cases in many sub-Sahara African countries.
- Trial name
- Palu-COVID (NCT05012280)
- Where
- Democratic Republic of the Congo
- Volunteers
- 238 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Coronavirus Infections
Prospective Monitoring of BNT162b2 Second Vaccination Booster Effects in Health Care Workers (HCW)
The SARS-CoV-2 virus causes severe respiratory illness and is an ongoing global pandemic. On December 12, 2020 the FDA approved Pfizer's BioNTech vaccine BNT162b2 which is a messenger RNA type of vaccine for use.
- Trial name
- NCT05516459
- Testing
- Pfizer BNT162b2 Vaccine
- Where
- Israel
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Covid-19
Clinical Application of Methylene Blue for Treatment of Covid-19 Patients
The severe acute respiratory syndrome caused by COVID-19 is now a global catastrophic event. Currently there is no approved drug or vaccine for the disease.
- Trial name
- Covid-19 (NCT04370288)
- Testing
- MCN (Methylene blue, vitamin C, N-acetyl cysteine)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
COVID-19
Epidemiological Study on Asymptomatic Infections and Mild Illness With Covid-19 in Shanghai
this study is to clarify the epidemiological characteristics of Omicron variant infected persons in Shanghai, such as distribution characteristics, host and clinical characteristics, disease outcome and risk factors.
- Trial name
- NCT05375786
- Testing
- Vaccination completion status
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Ruijin Hospital
Covid19
Monitoring Health Care Workers at Risk for COVID-19 Using Wearable Sensors and Smartphone Technology
This prospective study of health care workers utilizes wearable sensors, surveys and symptom logs, and biospecimens in an effort to improve self-monitoring practices for COVID-19 among health care workers and to provide key data…
- Trial name
- NCT04756869
- Testing
- COVID-19 Monitoring Using Wearable Sensors and Smartphone Technology
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Covid19
Amantadine for COVID-19
Introduction: Corona virus disease 19 (COVID-19) is a devastating pandemic. By early February 2021, more than 102 million people were infected globally with more than 2.2 million reported deaths.
- Trial name
- ACT (NCT04894617)
- Testing
- Amantadine, Lactose monohydrate
- Where
- Denmark
- Volunteers
- 226 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
COVID-19
Communities Fighting COVID Return to School
San Diego State University (SDSU), a designated Hispanic-serving institution, is partnering with Sweetwater Union High School District, an independent public school district serving 90% ethnic minority and a high proportion of…
- Trial name
- NCT05150860
- Testing
- At-home COVID-19 testing, Onsite COVID-19 testing
- Where
- United States
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
SARS CoV 2 Infection
Using Vibroacoustic Therapy in a Patient With Co-infection and COVID-19
This article describes a case of successful treatment of a 59-year-old man with sepsis as a result of periprosthetic infection against the background of severe SARS-CoV-2-19, who was hospitalized for 59 days, 57 of which were in…
- Trial name
- NCT05188482
- Testing
- vibroacoustic therapy
- Where
- Kazakhstan
- Volunteers
- 1 people
- Sponsor
- Astana Medical University
COVID-19
Non-inferiority Trial on Monoclonal Antibodies in COVID-19
Currently, 3 anti-SARS-CoV-2 monoclonal antibody products have received Emergency Use Authorizations from the Italian Medicines Agency (AIFA) for the treatment of mild to moderate COVID-19 in non hospitalized patients with…
- Trial name
- MANTICO (NCT05205759)
- Testing
- Bamlanivimab Etesevimab, Sotrovimab, Casirivimab-Imdevimab
- Where
- 20 sites in Italy
- Volunteers
- 319 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
COVID-19, Myocardial Injury
Myocardial Injury and Quality of Life After COVID-19
In this observational study follow-up and dynamic observation will be conducted on the participants recovered from pneumonia caused by COVID-19.
- Conditions
- COVID-19, Myocardial Injury, Myocarditis Post Infection
- Trial name
- NCT04794062
- Where
- Russia
- Volunteers
- 119 people
- Sponsor
- Voronezh Regional Clinical Consultative and Diagnostic Center
COVID, Safety Issues
Facial Hair, PPE and COVID-19
An observational cross sectional questionnaire study looking into facial hair of hospital doctors during the COVID-19 pandemic, and how personal protective equipment guidance has affected this.
- Trial name
- FACIAL HAIR (NCT04579627)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Corona Virus Infection
Placebo Controlled Trial to Evaluate Zinc for the Treatment of COVID-19 in the Outpatient Setting
This is a randomized, double-blind, placebo-controlled trial to assess the efficacy of zinc in a higher risk COVID-19 positive outpatient population.
- Trial name
- NCT04621461
- Testing
- Zinc Sulfate 220 MG
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- St. Francis Hospital, New York
Gait, Covid19
Breathing After COVID-19
This research; It will be done to perform thoracic movement analysis of young adult individuals who have survived COVID-19 and to compare them with those without a history of COVID-19.
- Conditions
- Gait, Covid19, Thorax Anomalies
- Trial name
- NCT04944342
- Testing
- No intervention.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Trakya University
Covid19, Diabetes
REsearching Covid-19 Outcomes in Diabetes (RECODE)
The purpose of this study is to observe any changes that may occur to certain organs following a confirmed diagnosis of COVID-19 in people with and without diabetes.
- Trial name
- RECODE (NCT04805970)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Coronavirus Disease 2019, Stroke
Impact of Changes in the Use of Care and Reorganization of the Healthcare System Linked to the Covid-19 Outbreak on the Quality of Care Pathways of Patients Suffering From Acute Myocardial Infarction and Stroke in Aquitaine (AVICOVID)
The Covid-19 pandemic and its health and societal consequences raise fears of a deterioration in the management of non-Covid-19 pathologies, particularly those requiring rapid treatment.
- Conditions
- Coronavirus Disease 2019, Stroke, Acute Myocardial Infarction
- Trial name
- AVICOVID (NCT04979208)
- Where
- France
- Volunteers
- 9,218 people
- Sponsor
- University Hospital, Bordeaux
SARS CoV 2 Infection, Alveolar; Injury
The Potential Role of sRAGE, KL-6, and SP-D as Prognostic Factors in Children With COVID-19
COVID-19 causes a wide spectrum of clinical illness, from upper respiratory symptoms to severe respiratory failure and death. Several plasma biomarkers -such as IL-6, C-reactive protein (CRP), D-dimer, the…
- Conditions
- SARS CoV 2 Infection, Alveolar; Injury, Children, Pneumonia, Viral
- Trial name
- NCT05619640
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Mental Health Disorder, Depression
Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
This study aims at evaluating the effectiveness of a mobile phone based intervention to prevent and manage mental health problems in healthcare workers at the frontline against COVID-19 in Spain.
- Conditions
- Mental Health Disorder, Depression, Posttraumatic Stress Disorder, Burnout
- Trial name
- PsyCovid_App (NCT04393818)
- Testing
- Intervention App
- Where
- Spain
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
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