Clinical trials: Rotator Cuff Injury
Rotator Cuff Tears
BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears
This study aims to evaluate the safety and effectiveness of arthroscopic rotator cuff repair augmented with the BioBrace® Implant vs.
- Trial name
- REinForce (NCT05997381)
- Testing
- Arthroscopic rotator cuff repair with BioBrace® Implant augmentation., Arthroscopic rotator cuff repair
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- CONMED Corporation
Rotator Cuff Tear, Rotator Cuff Syndrome
Lyophilized Platelet-Rich Plasma Lysate vs Dextrose Prolotherapy for Partial Rotator Cuff Tears
The goal of this clinical trial is to learn whether lyophilized platelet-rich plasma (PRP) lysate can improve shoulder symptoms, shoulder muscle strength, and tendon tear size in adults with partial-thickness rotator cuff tears…
- Conditions
- Rotator Cuff Tear, Rotator Cuff Syndrome, Rotator Cuff Arthropathy of Right Shoulder, Rotator Cuff Arthropathy of Left Shoulder
- Trial name
- NCT07789951
- Testing
- PRP lysate, Hypertonic dextrose
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- Taichung Veterans General Hospital
Rotator Cuff Tears, Rotator Cuff Injuries
Dermis on Demand Allograft Augmentation for Rotator Cuff Repair
The purpose of this study is to find out whether adding a human acellular dermal allograft (Dermis on Demand) during arthroscopic rotator cuff repair improves tendon-to-bone healing and lowers the rate of re-tear compared to…
- Trial name
- NCT07890831
- Testing
- Arthroscopic rotator cuff repair; Biological: Dermis on Demand, Arthroscopic rotator cuff repair
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Rotator Cuff Tears, Rotator Cuff Tendinitis
Treatment of Rotator Cuff Tears With Platelet Rich Plasma
The purpose of this study is to evaluate the safety and effectiveness of dual platelet rich plasma (PRP) injections into the rotator cuff insertion and the area of the tendon proximal to the insertion.
- Trial name
- NCT06481046
- Testing
- Platelet Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Rotator Cuff Tears, Rotator Cuff Injuries
Arthroscopic Rotator Cuff Repair With Long Head of Biceps Transposition and Acellular Dermal Matrix Augmentation for Large to Massive Incompletely Repairable Rotator Cuff Tears
Large-to-massive rotator cuff tears of the shoulder with poor tendon and muscle quality often cannot be fully repaired back to its footprint, and they have a high risk of re-tear.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Massive Rotator Cuff Tear
- Trial name
- SCR-ADM-repair (NCT07875556)
- Testing
- Rotator Cuff Repair, Long Head of the Biceps Tendon Transposition, Acellular Dermal Matrix (Allograft) Augmentation
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Tam Anh Research Institute
Rotator Cuff Tear, Pain Management
Percutaneous Tenotomy Versus Radiofrequency Ablation for Rotator Cuff Tear - Related Pain.
Rotator cuff tears are among the most common direct and indirect causes of chronic shoulder pain. Patients with irreparable rotator cuff tears face a choice of pain management options.
- Trial name
- NCT07872527
- Testing
- Percutaneous tenotomy of the long head of the biceps tendon (LHBT), Ultrasound guided radiofrequency ablation of the suprascapular nerve
- Volunteers
- 60 people
- Sponsor
- Centre of Postgraduate Medical Education
Shoulder Surgery, Shoulder Pain
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade.
- Conditions
- Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
- Trial name
- NCT04209504
- Testing
- Ultrasound, Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Rotator Cuff Tears, Rotator Cuff Injuries
Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study)
Treatment of rotator cuff tears with micro-fragmented adipose tissue is a minimal-invasive procedure with the potential to shorten and ease recovery, accelerate return to daily activity and work of thus with a potential capacity…
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Tear Arthropathy
- Trial name
- NCT06505135
- Testing
- Stem-cell treatment, Standard care
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Rotator Cuff Tears (RCTs)
SINEFIX-2022 Pilot Phase
Shoulder pain is one of the most commonly reported musculoskeletal complaints, which negatively affects upper limb use, night rest, daily life activities, work, sports performance and autonomy.
- Trial name
- NCT05721560
- Testing
- Rotator cuff repair with the SINEFIX
- Where
- Germany
- Volunteers
- 9 people
- Sponsor
- BAAT Medical Products B.V.
Rotator Cuff Tears
Intravenous Versus Intra-articular Tranexamic Acid for Visual Clarity During Arthroscopic Rotator Cuff Repair
This single-center, prospective, randomized, double-blind controlled trial evaluated whether intravenous (IV) or intra-articular (IA) administration of tranexamic acid (TXA) improves intraoperative visual clarity, compared with a…
- Trial name
- NCT07686705
- Testing
- Tranexamic acid (intra-articular), Tranexamic acid (intravenous)
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Konkuk University Medical Center
Rotator Cuff Tears, Rotator Cuff Injuries
Fibrin Clot Augmentation in Arthroscopic Rotator Cuff Repair
The aim of this study is to evaluate whether applying an autologous fibrin clot to the repair site improves tendon healing and clinical outcomes after arthroscopic rotator cuff repair.
- Trial name
- NCT07853950
- Testing
- Arthroscopic Rotator Cuff Repair, Autologous Fibrin Clot
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ataturk University
Rotator Cuff Tear, Sling
Patient Education and Sling Use After Shoulder Surgery
This study will evaluate whether educational pamphlets can help patients safely manage personal hygiene, household activities, and female-specific self-care while wearing a sling after surgery.
- Conditions
- Rotator Cuff Tear, Sling, Shoulder Pain
- Trial name
- NCT07851233
- Testing
- Control - Standard Postoperative Education, Intervention - Living with a Sling Educational Pamphlets
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Rotator Cuff Tears, Postoperative Pain Management
Pain Education After Rotator Cuff Surgery
Study Title: The Effect of Pain Neuroscience Education Combined with Conventional Rehabilitation on Pain Management and Functional Outcomes in Patients Undergoing Mini-Open Rotator Cuff Repair Purpose: This study aims to…
- Conditions
- Rotator Cuff Tears, Postoperative Pain Management, Shoulder Dysfunction, Kinesiophobia (Fear of Movement)
- Trial name
- PNE-RCS (NCT06886932)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Elif Dilara Durmaz
Rotator Cuff Tears, Shoulder Pain
Effect of Kinesio Taping After Rotator Cuff Surgery
This prospective randomized controlled trial evaluated whether adding Kinesio Taping (KT) to a standardized postoperative rehabilitation program improves early clinical recovery after arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Shoulder Pain, Post Operative Pain
- Trial name
- RCR-KT (NCT07375927)
- Testing
- Kinesio Taping, Standard Postoperative Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Olcay Yavuz
Rotator Cuff Tears, Rotator Cuff Injuries
Repeated Injections of Adipose-derived Stem Cells in Rotator Cuff Tears
The aim of the project is to investigate whether repeated implantations of micro-fragmented adipose tissue (MFAT), into the shoulder muscle can improve the outcome of standard surgical treatment for rotator cuff tears (RCT).
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Stem Cells
- Trial name
- NCT07592936
- Testing
- Adipose derived stem cell injection
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Rotator Cuff Tendinosis
Effects of Rotator Cuff Drills Versus Progressive Resistance Exercises on Chronic Rotator Cuff Tendinopathy
A single-blinded randomized clinical trial was conducted with 30 male overhead athletes (17-35 years) recruited from cricket clubs and sports complexes in Faisalabad.
- Trial name
- NCT07726030
- Testing
- Rotator cuff Drills, Progressive resistance exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Pain, Postoperative, Rebound Pain
Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery
Shoulder surgery often causes severe pain after the operation. To control this pain, doctors commonly perform a nerve block (interscalene brachial plexus block), which numbs the shoulder area.
- Conditions
- Pain, Postoperative, Rebound Pain, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- NCT07699744
- Testing
- Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Seoul National University Hospital
Rotator Cuff Injuries
Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears
The purpose of the study is to assess whether the REGENETEN™ Bioinductive Implant allows patients to get back to their everyday activities quicker than if the tendon is repaired by the standard repair technique 'Completion and…
- Trial name
- IMPACT (NCT05444465)
- Testing
- Isolated Bioinductive Repair, Completion and Repair
- Where
- 20 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Smith & Nephew, Inc.
Rotator Cuff Injuries, Rotator Cuff Tear
Ultrasound and Shear Wave Elastography for Assessment of the Quality of Rotator Cuff Muscles
Rotator cuff disorders are among the most frequent musculoskeletal causes of shoulder pain, weakness, and limited movement. In many individuals with rotator cuff disease, the damaged muscles gradually shrink (muscle atrophy) and…
- Conditions
- Rotator Cuff Injuries, Rotator Cuff Tear, Muscular Atrophy, Fatty Infiltration
- Trial name
- NCT07837583
- Volunteers
- 70 people
- Sponsor
- Assiut University
Rotator Cuff Tear, Telemedecine
Remote App-based Rehabilitation After Rotator Cuff Repair
The aim of this study was to evaluate the effectiveness of a mobile application for telemedicine in patients recovering from arthroscopic rotator cuff tendon repair.
- Conditions
- Rotator Cuff Tear, Telemedecine, Rotator Cuff Injuries
- Trial name
- NCT07555704
- Testing
- Telerehabilitation, Conventional home exercise program
- Where
- Vietnam
- Volunteers
- 102 people
- Sponsor
- Hanoi Medical University