Clinical trials: Rosacea, active
Papulopustular Rosacea
A Phase 2 Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib (LOU064) in Adult Patients With Papulopustular Rosacea (PPR)
This Phase 2 study aims to evaluate whether Bruton's tyrosine kinase (BTK) inhibition with remibrutinib can produce a clinically meaningful reduction in inflammatory lesions in adults with moderate-to-severe papulopustular…
- Trial name
- NCT07681271
- Testing
- LOU064
- Where
- 12 sites in United States, Bulgaria and 6 more
- Volunteers
- 100 people
- Sponsor
- Novartis Pharmaceuticals
Rosacea, Erythematotelangiectatic, Rosacea Subtype 1 (Erythematotelangiectatic)
Dermocosmetic Treatment for Facial Redness in Rosacea With or Without Laser Therapy
The aim of this clinical study is to evaluate the effectiveness and safety of a dermocosmetic product in reducing facial redness and visible blood vessels associated with erythematotelangiectatic rosacea.
- Trial name
- NCT07521462
- Testing
- Dermocosmetic tested product, Vascular laser treatment
- Where
- France
- Volunteers
- 50 people
- Sponsor
- ISISPHARMA
Atopic Dermatitis, Psoriasis
Determinants of Chronic Inflammatory Skin Disease Trajectories
Although it is well known that the clinical expression and course of chronic inflammatory skin diseases are highly variable, there are insufficient epidemiological data on this, and the factors that determine the manifestation…
- Conditions
- Atopic Dermatitis, Psoriasis, Lichen Planus, Alopecia Areata
- Trial name
- NCT05928169
- Testing
- Topical and systemic drugs
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Rosacea, Rosacea, Erythematotelangiectatic
Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea
A single arm, pilot study among individuals with rosacea and at least moderate flushing or rednesss will be enrolled in a 4-week trial of taVNS.
- Conditions
- Rosacea, Rosacea, Erythematotelangiectatic, Flushing
- Trial name
- NCT07600424
- Testing
- Transaricular vagus nerve stimulation (taVNS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Rosacea, Papulopustular, Rosacea, Erythematotelangiectatic
Rosacea Radiofrequency Microneedling
There are 3 main objectives of this proposal as follows: (1) to assess the efficacy of radiofrequency microneedling in the treatment of erythematotelangiectatic and or papulopustular rosacea, (2) to determine the potential for…
- Trial name
- NCT06801717
- Testing
- KTP Laser Therapy, Radiofrequency microneedling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Melasma, Rosacea
Microfocused Ultrasound for Facial Pigmentary Diseases and Rosacea
This clinical study will evaluate the efficacy and safety of microfocused ultrasound treatment in patients with facial pigmentary diseases and rosacea.
- Conditions
- Melasma, Rosacea, Periorbital Hyperpigmentation, Melanosis
- Trial name
- NCT07667972
- Testing
- Microfocused Ultrasound Treatment
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xiangya Hospital of Central South University
Facial Rosacea
Clinical Study of a Facial Cream for Rosacea
This study aimed to evaluate the efficacy, tolerability, and safety of Eucerin Skin Relief Multi-Repair Cream containing the active ingredient SenSiCel™ in improving facial rosacea.
- Trial name
- NCT07637032
- Testing
- ARM 1, ARM 2
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Rosacea
Analysis of the Microbiome in Rosacea
The skin and gut microbiome of rosacea patients differs from individuals without rosacea and that the microbiome suffers from unique derangements in rosacea patients following antibiotic therapy.
- Trial name
- NCT04108897
- Testing
- Doxycycline, Ivermectin Topical
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Skin Inflammation, Immunosenescence
Skin Inflammation in (Peri)Menopause: A Probiotic Intervention Proof of Concept Trial
This study will explore whether a daily probiotic drink containing Lactobacillus casei Shirota (LcS) can help improve immune function and reduce inflammation in women going through the menopausal transition.
- Conditions
- Skin Inflammation, Immunosenescence, Inflammation, Skin Health
- Trial name
- SIPPI (NCT07341087)
- Testing
- Lactobacillus casei Shirota (LcS) Probiotic Drink, Skimmed Milk Control Drink
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- King's College London
Erythematotelangiectatic Rosacea
The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic Rosacea
The efficacy and safety of anti-inflammation treatment (Hirudoid introduction followed by yellow light therapy) combined with tofacitinib and doxycycline in Chinese adult patients with mild to moderate erythematous telangiectatic…
- Trial name
- NCT07343635
- Testing
- Doxycycline, Hydroxychloroquine, Tofacitinib
- Where
- China
- Volunteers
- 186 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Ocular Rosacea
Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE)
To evaluate lotilaner treatment in patients with ocular rosacea.
- Trial name
- NCT07443202
- Testing
- lotilaner, Vehicle
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Rosacea
Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea
Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness.
- Trial name
- NCT06312813
- Testing
- Imipramine, Amitriptyline, Vehicle
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wright State University
Rosacea
Acupuncture for Refractory Rosacea: A Study on Its Effectiveness and Safety
This study is a randomized, multicenter, sham-controlled clinical trial designed to evaluate the efficacy and safety of acupuncture for patients with refractory rosacea.
- Trial name
- NCT07296497
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Xiangya Hospital of Central South University
Rosacea, Vascular Diseases
Vbeam Pro Pulse Dye Laser for the Treatment of Vascular Conditions
This is a clinical study to evaluate the safety and performance of the Vbeam Pro Laser System for the treatment of vascular indications, including rosacea and port wine stain birthmarks.
- Conditions
- Rosacea, Vascular Diseases, Port-Wine Stain
- Trial name
- NCT07290426
- Testing
- Vbeam Pro Laser Treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Erythematous Telangiectatic Rosacea
Efficacy and Safety Evaluation of CICAPLAST BAUME B5+ on Rosacea Accompanied by Sensitive Skin
In total, 72 eligible research participants were recruited in this 56-day study. The participants were divided into two groups-namely the Experimental Group and the Control Group-according to stratified randomization, with 36…
- Trial name
- NCT07106957
- Testing
- CICAPLAST BAUME B5+, Standard cream
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Beijing Sino-German Union Cosmetic Institute Co., Ltd.
Papular-pustular Rosacea, Papulopustular Rosacea (PPR)
Efficacy and Safety of Topical Clascoterone (WINLEVI) Cream 1% in Patients With Facial Acneiform Rosacea
To demonstrate the efficacy of Clascoterone cream 1% in reducing the size of sebaceous glands in study participants with acneiform rosacea.
- Conditions
- Papular-pustular Rosacea, Papulopustular Rosacea (PPR), Papulopustular Rosacea
- Trial name
- NCT06952517
- Testing
- Clascoterone Cream 1%
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Narrows Institute for Biomedical Research
Rosacea, Acne
Clinical Evaluation and Study of the Efficacy of a Centella Asiatica-Infused Facial Mask on Discosmetic Dermatosis
The purpose of this study was to investigate the efficacy and safety of repairing facial mask containing Asiaticum asiatica in treating disjunctive skin diseases.
- Conditions
- Rosacea, Acne, Centella, Melasma
- Trial name
- NCT06763367
- Testing
- Face mask containing Centella sinensis
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University