Clinical trials: Rolandic Epilepsy
Pain, Nausea
Why in Hospital - Factors Determining Time to Discharge Readiness After Arthroplasty Surgery
The purpose of this study is to evaluate patient related factors determining length of stay in hospital after arthroplasty surgery.
- Conditions
- Pain, Nausea, Vomiting, Dizzyness
- Trial name
- NCT01047371
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Hvidovre University Hospital
Treatment Resistant Depression (TRD)
Maintenance TMS in Treatment Resistant Depression
Electroconvulsive therapy (ECT) is one of the most efficacious treatments available for treatment-resistant depression (TRD). Although a maintenance ECT protocol exists, multiple barriers limit its use for long-term use.
- Trial name
- NCT06682299
- Testing
- Transmagnetic Stimulation, Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Austin Messner
Epilepsy, Rolandic
Association of Processing Speed Dysfunction and Brain Functional Abnormality in ECTS
Epilepsy with centrotemporal spikes (ECTS) is the most common epilepsy syndrome in children. Language impairment has been widely investigated in patients with ECTS, but little is known about the cognitive dysfunction of…
- Trial name
- NCT04954729
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Rolandic Epilepsy
Rolandic Epilepsy Genomewide Association International Study
We have discovered a small change in the genetic code which increases the risk of the brainwave abnormality that is found in rolandic epilepsy. We now wish to confirm this using a second much larger sample of patients.
- Trial name
- REGAIN (NCT03547050)
- Testing
- Blood draw, Existing samples
- Where
- 13 sites in United States, Argentina and 5 more
- Volunteers
- 210 people
- Sponsor
- King's College London
Rolandic Epilepsy, Benign Childhood Epilepsy With Centrotemporal Spikes
The Effect of Music Periodicity on Interictal Epileptiform Discharges
The purpose of this study is to determine if having children listen to the music of Wolfgang Amadeus Mozart (Sonata for Two Pianos in D Major, K.
- Conditions
- Rolandic Epilepsy, Benign Childhood Epilepsy With Centrotemporal Spikes, Epilepsy, Seizures
- Trial name
- NCT01515436
- Testing
- Mozart alternating with Beethoven, Beethoven alternating with Mozart
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Epilepsy
Levetiracetam for Benign Rolandic Epilepsy
This study is designed to test if the language problems commonly seen in children with benign rolandic epilepsy would improve by switching anticonvulsants to levetiracetam.
- Trial name
- NCT00181116
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Epilepsy
Genetics of Rolandic Epilepsy
The purpose of this study is to find the genes that cause Rolandic epilepsy and its related traits.
- Trial name
- NCT00282854
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- King's College London
Depressive Disorder, Major
Study on the Influence of Electroconvulsive Therapy (ECT) on Homocysteine Levels
Elevated homocysteine levels are associated with depression and cognitive impairment. When depression ameliorates due to treatment, homocysteine serum levels often normalize.
- Trial name
- NCT00370058
- Testing
- ECT treatment
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
BECTS, Epilepsy, Rolandic
Emotion Recognition in Benign Epilepsy of Childhood With Centro-Temporal Spikes (BECTS)
The social processes depend on complex cognitive mechanisms, which involve mainly the frontal and temporal lobe regions. Patients with early onset frontal and temporal lobe lesions might later develop important deficits in social…
- Trial name
- BECTS (NCT03465566)
- Testing
- IDS;MMSPE;CDI 2;CBCL;tests of facial expression evaluation
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Rolandic Epilepsy, Rolandic Epilepsy, Benign
Sleep Spindles and Memory in Rolandic Epilepsy
The investigators are recruiting children with Rolandic epilepsy and children without epilepsy (aged 4 years old and above) for a non-invasive brain imaging study using Magnetic Resonance Imaging (MRI)…
- Conditions
- Rolandic Epilepsy, Rolandic Epilepsy, Benign, Centrotemporal Epilepsy, Centrotemporal; EEG Spikes, Epilepsy of Childhood
- Trial name
- NCT04569708
- Testing
- Closed loop auditory stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Major Depressive Disorder, Suicide
Accelerated iTBS for Depression and Suicidality
The overall objective of this current study is to evaluate the feasibility, safety, and tolerability of "high dose" aiTBS in psychiatric inpatient and outpatients with treatment-refractory unipolar, non-psychotic major depressive…
- Trial name
- RAPID (NCT04441008)
- Testing
- Accelerated Intermittent Theta Burst (aiTBS), Electroconvulsive therapy (ECT)
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Benign Epilepsy With Centrotemporal Spikes
18F-FDG PET Imaging Analysis of Antiepileptic Drug Response in BECTS
This original article is a novel investigation on the metabolic characteristics of different patterns of antiepileptic drug (AED) responses in benign epilepsy with centrotemporal spikes (BECTS) patients using 18F-FDG PET imaging.
- Trial name
- NCT04357236
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Schizophrenia, Schizoaffective Disorder
Donepezil Double Blind Trial for ECT Memory Disfunction
This is a double blind randomized investigation of donepezil for patients suffering from schizophrenia, undergoing ECT. Patients will be randomized to receive either donezepil or plasebo, in order to gauge whether donezepil has a…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
- Trial name
- NCT00465283
- Testing
- Donepezil
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- BeerYaakov Mental Health Center
Epilepsy, Rolandic
Safety and Efficacy of Topamax Versus Carbamazepine in Benign Rolandic Epilepsy
The purpose of this study is to determine the efficacy and safety of Topiramate in comparison to Carbamazepine in Benign rolandic epilepsy.
- Trial name
- NCT00216567
- Testing
- topamax
- Volunteers
- 114 people
- Sponsor
- Janssen Korea, Ltd., Korea
Benign Epilepsy With Centrotemporal Spikes, Language Problems
Transcranial Magnetic Stimulation for BECTS
Benign epilepsy with centrotemporal spikes (BECTS) is the most common pediatric epilepsy syndrome. Affected children typically have a mild seizure disorder, but yet have moderate difficulties with language, learning and attention…
- Conditions
- Benign Epilepsy With Centrotemporal Spikes, Language Problems, Learning Disorders
- Trial name
- TMS4BECTS (NCT04325282)
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Benign Childhood Epilepsy With Centrotemporal Spikes
Electroclinical Effect of Steroid in Patients With Benign Childhood Epilepsy With Centrotemporal Spikes
Benign epilepsy with centro-temporal spikes is the most common type of focal epilepsy in children. It is known to be age-dependent and presumably genetic.
- Trial name
- NCT03490487
- Testing
- conventional antiepileptic drugs, oral steroid
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Benign Childhood Epilepsy With Centro-Temporal Spikes
Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children
This project examines how seizures, and abnormal brain activity, affect language skill in children with Benign Childhood Epilepsy with Centro-Temporal Spikes (BECTS).
- Trial name
- FIRST (NCT01521130)
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Epilepsy, Rolandic
HEAD-Study Optimizing the Treatment of Children With BECTS
The investigators hypothesize that Levetiracetam is as effective as Sulthiame in the treatment of children with BECTS. Patients entering the HEAD-Studie are either treated with Leveitracetam or Sulthiame over a 6 months period.
- Trial name
- HEAD (NCT00471744)
- Testing
- Treatment with levetiracetam or sulthiame over a six-month period.
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Rolandic Epilepsy
Changing Agendas on Sleep, Treatment and Learning in Epilepsy
Rolandic epilepsy (RE) is the most common type of epilepsy. Children with RE have seizures and can often find that their learning, sleep, behaviour, self-esteem and mood are affected.
- Trial name
- CASTLE (NCT04610879)
- Testing
- Carbamazepine, Levetiracetam, Parent based sleep (PBS) intervention
- Where
- 3 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- King's College London
Benign Childhood Epilepsy With Centro-temporal Spikes (BCECTS), Focal Cryptogenic Epilepsy of Childhood
Brain Maturation in Children With Localization Related Epilepsy
This project intends to investigate children with idiopathic and cryptogenic localization related epilepsies, using a longitudinal assessment of structural and functional MRI data, in relation to neuropsychological evaluation.
- Conditions
- Benign Childhood Epilepsy With Centro-temporal Spikes (BCECTS), Focal Cryptogenic Epilepsy of Childhood, Cryptogenic Epilepsy of Childhood
- Trial name
- DYNAMAT (NCT02648529)
- Testing
- MRI, functional MRI (fMRI), neuropsychological assessment
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon