Clinical trials: Robotic Radical Prostatectomy
Lymphoceles Following Pelvic Lymph Node Dissection
Cold Plasma for the Reduction of Lymphoceles Following PLND
This study protocol will evaluate the efficacy of Bovie Medical's J-Plasma® helium based plasma technology in the reduction of lymphoceles following pelvic lymph node dissection (PLND) during robotic assisted radical…
- Trial name
- NCT02658851
- Testing
- J-Plasma
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Apyx Medical
Prostate Cancer
Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy
A Study of STM-416p Administered Intraoperatively to Patients Undergoing Radical Prostatectomy
- Trial name
- NCT06450106
- Testing
- STM-416p
- Where
- 4 sites in United States, Australia
- Volunteers
- 18 people
- Sponsor
- SURGE Therapeutics
Urologic Cancer, Prostate
Comparison of the Integrated Posterior-Anterior-Lateral Approach and the Posterior Approach in Robotic Radical Prostatectomy
This study aims to compare perioperative, pathological, and early functional outcomes of PAL （Posterior, Anterior and Lateral）combined approach RARP and posterior approach (with Retzius space preserved) RARP in the treatment of…
- Conditions
- Urologic Cancer, Prostate, Robot Assisted Laparoscopic Radical Prostatectomy
- Trial name
- NCT07305142
- Testing
- PAL combined approach group, posterior approach group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Prostate Cancer, Positron Emission Tomography
Radio-guided Surgery With DROP-IN Beta Probe for 68Ga-PSMA, in High-risk Prostate Cancer Patients Eligible for Robotic-assisted Radical Prostatectomy.
The goal of this observational study is to evaluate the diagnostic efficacy and the safety of the combined approach with β-probe and 68Ga-PSMA-11 PET/CT in the correct identification of lymph node metastases, in high-risk…
- Conditions
- Prostate Cancer, Positron Emission Tomography, PSMA
- Trial name
- NCT05596851
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- European Institute of Oncology
Urinary Incontinence
Does Posterior Reconstruction of the Rhabdosphincter Improve Early Recovery of Continence After Robotic-Assisted Radical Prostatectomy?
The present study is a multicenter randomized, controlled trial, whose aim is to verify the effect of the posterior reconstruction of the rhabdosphincter after robot-assisted radical prostatectomy on early recovery of urinary…
- Trial name
- PRR (NCT01809522)
- Testing
- Posterior reconstruction of the rhabdosphincter
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Robot-Assisted Radical Prostatectomy Training, Prostatectomy
Comparing Two Training Methods for Learning Robot-Assisted Radical Prostatectomy
This randomized non-inferiority study evaluates whether a robot-assisted radical prostatectomy (RARP) training pathway incorporating the IMRA Surgical Prostatectomy Class V Hydrogel Model is as effective as the current standard…
- Trial name
- NCT07669974
- Testing
- IMRA-Enhanced Training Pathway, Standard Training Pathway
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Orsi Academy
Prostate Adenocarcinoma, Incontinence Stress
A Prospective Study to Evaluate the Impact of Maximal Urethral Length Preservation Technique During Robotic Laparoscopic Prostatectomy on the Stretched Flaccid Penile Length and Continence
After robotic prostatectomy, besides erectile function and achievement of oncological control, staying dry is also a very important desire expressed frequently by the patients.
- Conditions
- Prostate Adenocarcinoma, Incontinence Stress, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- NCT05735223
- Testing
- Maximal urethral length preservation technique of robot assisted radical prostatectomy (RALP).
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Larkin Health System
Neuromuscular Blockade
Deep Neuromuscular Blockade During Robotic Radical Prostatectomy
Basic requirement for safe performance of the robotic intra-abdominal surgery is a calm and clear surgical field after the introduction of a capnoperitoneum. That can be enabled by a neuromuscular blockade.
- Trial name
- NCT02513693
- Testing
- Standard neuromuscular blockade, Deep neuromuscular blockade
- Where
- 2 sites in Czechia
- Volunteers
- 80 people
- Sponsor
- Palacky University
Male Erectile Disorder, Prostate Cancer
Vacuum Erection Device in Improving Recovery of Erectile Function in Patients With Prostate Cancer Undergoing Surgery
The purpose of this study is to determine which technique in using a vacuum erection device (VED) is best. Erectile dysfunction (ED) after robotic prostate cancer surgery is a concern for both the surgeon and the patient.
- Conditions
- Male Erectile Disorder, Prostate Cancer, Sexual Dysfunction
- Trial name
- NCT01660152
- Testing
- Sexual Health Inventory for Men (SHIM) questionnaire administration, management of therapy complications, Daily vacuum therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Prostate Cancer, Radical Prostatectomy
Impact of a Multimodal Prehabilitation Program Before Robotic-assisted Radical Prostatectomy.
The aim of the study is to verify whether a multimodal prehabilitation program prior to robotic-assisted radical prostatectomy (RARC) contributes to a faster recovery of quality of life after surgery.
- Trial name
- NCT05553327
- Testing
- Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clinic of Barcelona
Prostate Cancer
Feasibility of Day-surgery Management for Patients Undergoing Robotic Radical Prostatectomy: a Randomized Trial
To compare the day-surgery approach versus routine management in patients undergoing robotic radical prostatectomy, aimed at evaluating the feasibility of a one-day hospitalization regimen for robotic radical prostatectomy.
- Trial name
- NCT06891664
- Testing
- Day surgery regimen for patients, Ordinary management
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Regina Elena Cancer Institute
Prostate Cancer
Use of Hypothermia During Robotic Prostatectomy
Robotic assisted laparoscopic radical prostatectomy (RLP) has gained widespread acceptance as a standard treatment for clinically localized prostate cancer.
- Trial name
- NCT00915031
- Testing
- UroCool
- Where
- United States
- Volunteers
- 738 people
- Sponsor
- University of California, Irvine
Incontinence
Study of Endorectal Cooling During RARP to Minimize Trauma and Promote Earlier Return to Continence
Localized cooling/hypothermia using the UroCool System during robotic-assisted radical prostatectomy (RARP) surgery results in an improved overall return to continence, (defined as not wearing any protective urinary pads)…
- Trial name
- UroCool (NCT01920035)
- Testing
- UroCool (Local cooling/hypothermia)
- Where
- 3 sites in United States, Germany
- Volunteers
- 200 people
- Sponsor
- ZOLL Circulation, Inc., USA
Cancer of Prostate, Prostate Adenocarcinoma
Retzius-sparing Technique in Robotic-assisted Radical Prostatectomy
The objective of this study is to compare the short-term and 1-yr follow-up functional outcomes of retzius-repairing robot-assisted radical prostatectomy (RR-RARP) with retzius-sparing (RS) RARP.
- Conditions
- Cancer of Prostate, Prostate Adenocarcinoma, Urinary Incontinence,Stress, Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- NCT05224024
- Testing
- Retzius-repairing robot-assisted radical prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University
Prostate Cancer
Early Start of Oral Sildenafil 100mg for Erectile Dysfunction After Robotic Assisted Laparoscopic Radical Prostatectomy
The investigators try to investigate the benefit of early administration (immediately after urethral catheter removal) of sildenafil after nerve-sparing RALP for 3 months.
- Trial name
- SILRALP (NCT01054001)
- Testing
- sildenafil 100mg
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Bundang Hospital
Hypothermia; Anesthesia
The Comparison of Remimazolam With Propofol in Core Body Temperature
1. Core body temperature is normally tightly regulated to within a few tenths of a degree. The major thermoregulatory defences in humans are sweating, arteriovenous shunt vasoconstriction, and shivering. 2.
- Trial name
- NCT05215834
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Wonkwang University Hospital
Prostate Cancer (Adenocarcinoma), Blood Loss, Postoperative
EFFICACY OF INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION ON THE POSTOPERATIVE BLOOD LOSS IN PATIENTS UNDERGOING RARP FOR THE TREATMENT OF PROSTATE CANCER
We perform a multicenter randomized controlled prospective study with superiority trial design, in which the polysaccharide ARISTA™ AH hemostat agent is applied to the neurovascular bundle areas after prostate removal, during…
- Conditions
- Prostate Cancer (Adenocarcinoma), Blood Loss, Postoperative, Erectile Function
- Trial name
- ARISTA (NCT06822036)
- Testing
- Arm A - Application of 5g of ARISTA™ AH
- Where
- 3 sites in Germany
- Volunteers
- 362 people
- Sponsor
- St. Antonius Hospital Gronau
Localized Prostate Cancer, Postoperative Urinary Incontinence
Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled Trial
The goal of this double-blind, randomized, placebo-controlled study is to evaluate whether oxybutynin chloride extended-release tablets can improve early continence recovery after robot-assisted radical prostatectomy (RARP) in…
- Trial name
- NCT06966778
- Testing
- Oxybutynin chloride extended-release tablets 5mg/tab, 2 tab, PO, qd.
- Where
- Taiwan
- Volunteers
- 135 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
The Impact of Low Pressure Pneumo in RARP II
The purpose of this study is to evaluate clinical significance of low pressure pneumoperitoneum during robotically assisted radical prostatectomy (RARP).
- Trial name
- NCT04394676
- Testing
- Pressure applied during RARP
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Metro Health, Michigan
Robotic-Assisted Radical Prostatectomy, Locally Advanced Prostate Cancer
Improved Robotic-Assisted Radical Prostatectomy for Locally Advanced Prostate Cancer: Bladder Suspension and Preliminary Outcomes
This study is a prospective, single-center clinical trial. It aims to establish an improved robotic-assisted radical prostatectomy for treating locally advanced prostate cancer.
- Conditions
- Robotic-Assisted Radical Prostatectomy, Locally Advanced Prostate Cancer, Bladder Suspension
- Trial name
- NCT06977906
- Testing
- conventional Robotic-assisted radical prostatectomy group, Improved Robotic-assisted radical prostatectomy group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University