Clinical trials: Risk-Taking
Alcohol Consumption
Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors
Background: People who binge drink are more likely to have risky sexual encounters, and alcohol changes brain activity associated with reward decisions related to those behaviors.
- Trial name
- NCT04360018
- Testing
- Alcohol beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Drinking, Self Efficacy
ChangeGradients: Promoting Adolescent Health Behavior Change
As most adolescents visit a healthcare provider once a year, health behavior change interventions linked to clinic-based health information technologies hold significant promise for improving healthcare quality and subsequent…
- Conditions
- Alcohol Drinking, Self Efficacy, Adolescent Behavior, Risk-Taking
- Trial name
- NCT04110756
- Testing
- ChangeGradients
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Suicidal Ideas, Suicidal Ideation
Exploratory Analysis of Interpersonal and Intrapersonal Psychological Processes Implied in Risk-taking and Suicidal Behaviors, in Adult and Adolescent At-risk
In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Risk-taking
- Trial name
- RISKY (NCT06921226)
- Testing
- Psychological Processes, Risk-taking variables, Suicidal ideation and behavior
- Where
- 3 sites in France
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Opioid Use Disorder, Dual Diagnosis
Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness
Homelessness severely affects health and well-being and is particularly negative for youth. Between 70-95% of youth experiencing homelessness (YEH) report problem substance use and 66-89% have a mental health disorder.
- Conditions
- Opioid Use Disorder, Dual Diagnosis, Housing Problems, Mental Disorder in Adolescence
- Trial name
- NCT06311838
- Testing
- Motivational Interviewing/Community Reinforcement Approach (MI/CRA), Strengths-Based Outreach and Advocacy (SBOA ), Services as Usual (SAU)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Sleep Quality, Premature Labor
Music Therapy in the Threat of Premature Birth
The scope of the study covers the effects of music therapy on risk perception levels and sleep quality in pregnant women hospitalized due to the diagnosis of premature birth threat.
- Conditions
- Sleep Quality, Premature Labor, Risk-Taking
- Trial name
- NCT05602883
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Communication, Message Perception
Messages That Motivate: Communicating Alcohol-Related Breast Cancer Risk to Young Adult Women
This is an online cross-sectional experimental survey study examining two cancer communication questions: 1) What features of social media messages communicating the breast cancer risks from alcohol consumption will motivate…
- Conditions
- Communication, Message Perception, Alcohol, Cancer Prevention
- Trial name
- MEMO (NCT07802054)
- Testing
- Risk Message, Efficacy Message, Industry Deception
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
HIV, Opioid Dependence
Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users
To conduct a randomized clinical trial (RCT) of a community-friendly behavioral intervention designed to reduce HIV risk behavior among injection drug users (IDUs) in drug treatment by comparing risk-behavior outcomes of four…
- Trial name
- NCT01741350
- Testing
- Community-friendly Health Recovery Program, Time-and-Attention-Matched Control Condition
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- University of Connecticut
Risk Behavior, Cognitive Decline
Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention
Alzheimer's Disease (AD) and other Dementias have far-reaching consequences on the lives of sufferers and their loved ones, not to mention the impact on the healthcare system.
- Trial name
- NCT06748625
- Testing
- Luci Coach-Assisted Intervention
- Where
- Canada
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- LuciLab
Risk Behavior, Cognitive Decline
Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention
The overarching aim is to develop and deploy a multidomain intervention delivered on a mobile application to help older adults reduce their risk for dementia by improving a set of modifiable lifestyle risk factors associated with…
- Trial name
- NCT04616794
- Testing
- Cognitive Engagement Group, Physical Activity Group, Diet Group
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- LuciLab
HIV, Risk Behavior
Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior
Project SPACE is a micro-randomized trial evaluating the proximal effects theory-based text messages on alcohol use and sexual HIV risk behaviors among HIV-negative young adult men at the day-level.
- Conditions
- HIV, Risk Behavior, Alcohol Abuse
- Trial name
- NCT07769580
- Testing
- CLT- Concrete text messages, CLT- Abstract text messages, Control messages
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Emory University
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hiv
Evaluation of the Preventing AIDS Through Live Movement and Sound (PALMS) Intervention for Minority Adolescents
The purpose of this program evaluation is to determine whether the Preventing AIDS Through Live Movement and Sound (PALMS) group-level intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing of…
- Trial name
- NCT00137644
- Testing
- Preventing AIDS Through Live Movement and Sound (PALMS)
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Child Abuse, Child Neglect
Fostering Healthy Futures for Teens: An RCT
This study will implement and evaluate a mentoring program designed to promote positive youth development and reduce adverse outcomes among maltreated adolescents with open child welfare cases.
- Conditions
- Child Abuse, Child Neglect, Risk Behavior, Delinquency
- Trial name
- FHF-T (NCT03707366)
- Testing
- FHF-T
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Denver
Mild Traumatic Brain Injury, Suicidal Ideation
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
The investigators hope to develop a treatment for suicidal ideation (SI), impulsivity and functional impairments (such as difficulties in social and work settings) that occur after a mild traumatic brain injury (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Suicidal Ideation, Impulsivity
- Trial name
- NCT05647044
- Testing
- intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Unsafe Sex, Risk-Taking
Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men and Using Oral Tenofovir Disoproxil Fumarate/ Emtricitabine (TDF/FTC) for HIV Pre-Exposure Prophylaxis (PrEP)
The study ANRS 174 Doxyvac is a clinical trial that will use Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex with Men and using oral TDF/FTC for HIV Pre-Exposure Prophylaxis (PrEP) and…
- Trial name
- DOXYVAC (NCT04597424)
- Testing
- Experimental: doxycycline, Bexsero® vaccine
- Where
- 9 sites in France
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Behavior, Risk
Breast Cancer Study Tracking Risk Awareness of Alcohol Consumption and Improving Knowledge in Young Adult Women
This randomized trial aims to test the effects of co-created breast cancer counter marketing intervention messages for reducing alcohol consumption and impacting awareness and beliefs about the breast cancer risks from alcohol…
- Trial name
- B-Track (NCT07320664)
- Testing
- Alcohol and Breast Cancer Risk Messages, Skin Cancer Risk Messages
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Insomnia, Impulsivity
Effects of CBT-I on Impulsivity and Risk Taking in Youths With Insomnia
Insomnia is prevalent in adolescents. Impulsive behaviours and excessive risk-taking have been linked to the manifestation of psychopathology in youths.
- Conditions
- Insomnia, Impulsivity, Risk-Taking
- Trial name
- NCT07399964
- Testing
- Cognitive Behavioural Therapy for Insomnia, Health-related Psychoeducation
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- The University of Hong Kong
Behavior, Risk
Human Laboratory Study of the Effects of Nicotine Product Claims on Appeal, Perceptions, and Use Behavior
This study evaluates knowledge, feelings and thoughts regarding nicotine products among young adults who are susceptible to but do not use tobacco/nicotine and adults who use tobacco/nicotine.
- Trial name
- NCT06192316
- Testing
- 3x3 between-subjects experimental exposure
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Risk-Taking, Adolescent Behavior
Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects
Adolescence is a time of biological and behavioral changes that can lead to risky and dangerous behaviors, and African-American youth are highly vulnerable to the consequences of risky behavior, including HIV/AIDS and violence…
- Trial name
- NCT03370393
- Testing
- Pathways for African-Americans' Success (PAAS)
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine