Clinical trials: Rhinoplasty Surgery
Nasal Defect
Non-Surgical Rhinoplasty Using PDO Threads
To determine the effects of absorbable Polydioxanone (PDO) thread non-surgical revision rhinoplasty on first impressions and quality of life (FACE-Q scale) in 10 patients who desire further changes to their nasal tip and/or nasal…
- Trial name
- NCT04769427
- Testing
- PDO max threads
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Ecchymosis
The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery
Arnica montana is a homeopathic drug that is made in accordance with the official methods of the Homeopathic Pharmacopoeia of the United States (HPUS) and is commonly used by cosmetic surgeons throughout the world, although there…
- Trial name
- NCT01164644
- Testing
- Arnica montana
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Plastic Surgery Procedures
Non-surgical Rhinoplasty After Nasal Skin Cancer Reconstruction: Enhancing Aesthetic Outcomes
Reconstruction of the nasal pyramid after skin cancer is a complex surgery, often involving multiple stages. For some patients, the final result may be considered insufficient, affecting their quality of life and leading to…
- Trial name
- NCT07094620
- Testing
- Non-surgical rhinoplasty
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Reduce Edema and Ecchymosis After Rhinoplasty
Effect of Step Count on Edema After Rhinoplasty
Rhinoplasty surgery is being performed in increasing numbers in our country and around the world. After rhinoplasty surgery, patients experience swelling and bruising (ecchymosis) in their eyes.
- Trial name
- stepcount (NCT06202573)
- Testing
- rhinoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Istinye University
Rhinoplasty, Oxidative Stress
Effect of ORI-guided Oxygen Titration on Oxidative Stress in Rhinoplasty Surgery
The aim of this study is to evaluate whether the use of Oxygen Reserve Index (ORİ) can prevent hyperoxia in patients undergoing rhinoplasty surgery and whether it can reduce oxidative stress caused by hyperoxia.
- Conditions
- Rhinoplasty, Oxidative Stress, Hyperoxia, Oxygen Reserve Index
- Trial name
- NCT07158073
- Testing
- FiO₂ titration, under the guidance of ORI, Conventional oxygen administration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pain, Postoperative, Rhinoplasty
Sphenopalatine Ganglion Block in Septorhinoplasty
Septorhinoplasty is a widely performed surgery that aims to correct both functional and aesthetic problems of the nose. Despite its expected clinical benefits, septorhinoplasty surgery causes postoperative pain, which affects the…
- Trial name
- NCT06157970
- Testing
- Sphenopalatine Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Hypotension
Comparisons Between Dexmedetomidine and Magnesium Sulfate in Controlled Hypotension During Rhinoplasty Surgeries
General anesthesia organizes the best option for controlled blood pressure during rhinoplasty surgery. The primary agent applied in controlling hypotension should have particular unique characteristics.
- Trial name
- NCT05880693
- Testing
- Dexmedetomidine, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- mohamed
Rhinoplasty, Depth of Anesthesia
Processed EEG Monitoring During Controlled Hypotension in Patients Undergoing Rhinoplasty
This prospective observational study evaluates intraoperative processed electroencephalography parameters in adult patients undergoing elective rhinoplasty under total intravenous anesthesia with controlled hypotension.
- Conditions
- Rhinoplasty, Depth of Anesthesia, Surgical Bleeding, Postoperative Recovery
- Trial name
- NCT07671781
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Gazi University
Hypotension, Surgery-Complications
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension
In this study, the effects of nicardipine and esmolol applied for controlled hypotension in rhinoplasty on hemodynamics and regional renal oxygenation will be investigated.
- Conditions
- Hypotension, Surgery-Complications, Oxygen Deficiency
- Trial name
- NCT05430724
- Testing
- Controlled hypotention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yuzuncu Yil University
Deformity of Nasal Cartilage
Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty
The purpose of this research is to determine the effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty on First Impressions and Quality of Life determined by using the FACE-Q Scale.
- Trial name
- NCT04169308
- Testing
- Restylane-L® Filler injection
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Hypotensive Anesthesia
Regional Block of the Nose for Hypotensive Anaesthesia in Septo-rhinoplasty
Septorhinoplasty is a cosmetic surgery that many people are choosing to undergo. It can be done under general anesthesia, twilight anesthesia or regional anesthesia.
- Trial name
- NCT03774693
- Testing
- General anesthesia with fentanyl boluses, Regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Sleep Apnea, Obstructive
Virtual Surgery of the Upper Airways
Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances.
- Trial name
- VirtuOSA (NCT04829201)
- Testing
- functional septorhinoplasty or oropharyngeal/orthognathic surgery
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Norwegian University of Science and Technology
Surgical Incision, Nose Deformity
Rhinoplasty Scar Comparison
Traditional suture closure of the columellar scar in rhinoplasty is achieved with permanent skin sutures. These sutures create less inflammation and are thought to lead to improved final scar outcomes.
- Trial name
- NCT03748459
- Testing
- Closure with Permanent Suture, Closure with Resorbable Suture
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Pain, Postoperative, Surgery--Complications
Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.
The primary aim of this study is to evaluate whether celecoxib (CELEBREX) is equivalent to acetaminophen-codeine-caffeine (TYLENOL# 3) for the management of pain after primary elective open septorhinoplasty with osteotomies.
- Conditions
- Pain, Postoperative, Surgery--Complications, Opioid Analgesic Adverse Reaction, Opioid Use
- Trial name
- NCT04259333
- Testing
- Celecoxib 200mg, Acetaminophen, Codeine Drug Combination
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Blake Raggio
Preoperative Anxiety, Postoperative Delirium
Effects of Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Septo/Rhinoplasty Surgery
Effects of Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Septo/Rhinoplasty Surgery
- Trial name
- NCT07010042
- Testing
- The Beck Anxiety Inventory (BAI) of adult patients
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Zonguldak Bulent Ecevit University
Rhinoplasty
Effect of Use of Endotracheal Tube With Subglottic Suction in Rhinoplasty
Suction Above Cuff Endotracheal Tube (SACETT) has a dorsal port above the cuff designed to allow continuous or intermittent suctioning of secretions from the subglottic space.
- Trial name
- NCT03584503
- Testing
- Suction Above Cuff Endotracheal Tube
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Yuzuncu Yil University
Controlled Hypotension for Nasal Surgeries
Effects of Different MAP Targets on Ocular Perfusion and Optic Nerve Microvasculature During Rhinoplasty
This randomized controlled trial aims to evaluate the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on ocular perfusion and optic nerve head microvasculature in patients undergoing…
- Trial name
- NCT07832305
- Testing
- Lower MAP Target Strategy (50-60 mmHg), Higher MAP Target Strategy (60-70 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Anesthesia, Local
The Effect of Bilateral Infraorbital+ Infratrochlear Nerve Block for Rhinoplasty Operations
The aim of our study is to examine the effect of bilateral infraorbital and infratrochlear nerve blocks for rhinoplasty operations on perioperative remifentanil need and postoperative pain scores.
- Trial name
- NCT05671237
- Testing
- bilateral infraorbital+infratrochlear block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hypotension During Surgery
Controlled Hypotension in Rhinoplasty and Septoplasty: Incidence of Cognitive Dysfunction and Delirium
Controlled hypotension application is a commonly preferred anesthesia practice during surgical procedures, particularly in regions with rich tissue perfusion, aiming to reduce bleeding, enhance surgical field visibility, and…
- Trial name
- NCT06238973
- Testing
- Group Low, Group Middle
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.