Clinical trials: Rhinitis, Allergic, Perennial
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Optimal Concentration of Dermatophagoides Pteronyssinus (Dp) Allergen Extract for Skin Prick Test (SPT) of Thai Population
The purpose of this study is to determine the appropriate concentration of diagnostic reagent of house dust mite (Dp) to be used in diagnostic allergy skin prick test among Thai population with allergic rhinitis.
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Skin Prick Test
- Trial name
- DSPT (NCT01172613)
- Where
- 2 sites in Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Rhinitis, Allergic, Perennial
The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic Rhinitis
Some people with nasal allergy symptoms continue to have symptoms even after treatment with a nasal steroid spray. The purpose of this study is to see if these patients are helped by adding another medication (montelukast) to…
- Trial name
- NCT00119015
- Testing
- Montelukast, Fluticasone propionate
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Exercise Induced Asthma, House Dust Mite Allergy
Epigenetic Regulation of Exercise Induced Asthma
The purpose of this study is to investigate the micro ribonucleic acid (mRNA) profiles of patients with EIA without allergic sensitization and EIA with house dust mite sensitization compared to that of healthy controls.
- Trial name
- NCT05174689
- Testing
- Exercise challenge in the cold chamber (ECC), mRNA profile, standard diagnostic
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces measurable increases in neutrophil content of induced…
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Asthma
- Trial name
- NCT00839189
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis
Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) affects up to 12.5% of the US population and has a significant disease burden. The recommended medical management of CRS includes large-volume, low-pressure saline lavage, systemic antibiotics, and…
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis
- Trial name
- NCT03705793
- Testing
- Mometasone Furoate Nasal Irrigation, Mometasone Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Rhinitis, Allergic, Nonseasonal
Nasal Irritation Study: Individual Factors in Nasal Irritant Sensitivity
This study seeks to document differences in nasal irritant sensitivity within the population. The investigators are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant…
- Trial name
- NCT00041821
- Testing
- Nasal irritation thresholds and irritant provocation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma, Rhinitis, Allergic, Perennial
Single Rising Dose (SRD), Multiple Rising Dose (MRD) Study of BI 671800 in Healthy Asian Volunteers
The primary objective of the current study is to investigate the safety and tolerability of BI 671800 HEA in healthy Chinese male volunteers following single oral administration, and healthy Japanese male volunteers following…
- Trial name
- NCT01216384
- Testing
- BI 671800
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Rhinitis, Allergic, Perennial
Long Term Safety Of GW685698X Via Nasal Biopsy
Long term safety (52 weeks) of GW685698X on the nasal mucosa via nasal biopsy with an active control group (Nasonex®) and a healthy volunteers control group in subjects 18 years old with perennial allergic rhinitis .
- Trial name
- NCT00224523
- Testing
- GW685698X, mometasone furoate
- Where
- 4 sites in Belgium, Netherlands
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Allergic Asthma, Bronchial Inflammation
Fish Oil and Asthma in House Dust Mite Allergy
Native populations consuming high amounts of fish suffer less from allergic diseases. The purpose of this study is to determine whether polyunsaturated fatty acids (fish oil) might have a disease modifying influence on asthmatics…
- Conditions
- Allergic Asthma, Bronchial Inflammation, House Dust Mite Allergy
- Trial name
- NCT00380926
- Testing
- polyunsatturated fatty acids (fish oil)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Rhinitis, Allergic, Perennial
Single Dosing Clinical Trial of HL151
The purpose of this study is to assess the pharmacokinetic characteristics of bepotastine after single oral administration of TALION tab, a IR formulation of bepotastine as reference drug and HL151, a SR formulation of…
- Trial name
- NCT02682745
- Testing
- HL151, TALION tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Asthma With Allergic Rhinitis
Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS)
The goal of this clinical trial is to learn about how well tezepelumab (pronounced TEZ e PEL ue mab), a Health Canada-approved drug for severe asthma, works in participants with coexisting allergic asthma and allergic rhinitis…
- Trial name
- TEZARS (NCT06189742)
- Testing
- Tezepelumab
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis
Rhinitis, Rhinitis, Allergic
Short and Mid-term Repeatability of Active Anterior Rhinomanometry (AAR) Measurements in Paediatric Age
Longitudinal, observational study to assess the short-term (test re-test) and mid-term (within the span of 28 days) repeatability of active anterior rhinomanometry (AAR) measures on 4 parallel groups of children with different…
- Conditions
- Rhinitis, Rhinitis, Allergic, Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
- Trial name
- Rhino-Rep (NCT03286049)
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Asthma, Dermatitis, Atopic
Impact in Off-spring of Mothers After Perinatal Daily Intake of a Probiotic
A probiotic (Lactobacillus rhamnosus GG) supplement to pregnant women the last four weeks of pregnancy and three months after birth is expected to give a 40% reduction in risk of atopic sensitisation and allergic disease at two…
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Allergic, Perennial
- Trial name
- NCT00159523
- Testing
- Probiotic
- Where
- Norway
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Rhinitis, Allergic, Perennial and Seasonal
Pharmacokinetic Study of Levocetirizine Oral Solution
This study will be a single center, open-label, randomized, single dose, in the fasted condition and 2-way crossover study to evaluate the pharmacokinetics, the safety and tolerability of levocetirizine oral solution 5 mg and…
- Trial name
- NCT01622283
- Testing
- Levocetirizine, Cetirizine
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Perennial Allergic Rhinitis
Levocetirizine Effect on Nasal Nitric Oxide and Nasal Eosinophils in Subjects With Perennial Allergic Rhinitis
The purpose of this study is to noninvasively measure the anti-inflammatory effect of levocetirizine after two weeks of treatment in allergic rhinitis subjects.
- Trial name
- NCT00894231
- Testing
- levocetirizine (Xyzal)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AAADRS Clinical Research Center
House Dust Mite Allergy
Role of the Central Nervous System in Allergic Rhinitis
In order to evaluate the effects a nasal provocation on the activation of different brain regions, the investigators want to set up a clinical trial investigating the short-term effects of a nasal histamine provocation in healthy…
- Trial name
- NCT01777464
- Testing
- histamine
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients
Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders
This research study is an observational, single site study quantifying expression of biomarkers of respiratory disease in nasal fluid using the ABEL microsampler device.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients, Asthma and Rhinitis, Asthmatic Patients
- Trial name
- ENBOARD (NCT06661252)
- Testing
- ABEL microsampler device
- Where
- Australia
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Diag-Nose Medical Pty Ltd
Pollen Allergy, Venom Allergy
Identification of B Regulatory Cells by Flow Cytometry
The goal of this laboratory and observational study is to develop a test to quantify B-regulatory cells in blood. This will be used to detect changes in B-regulatory cell populations in pollen and insect venom allergic patients…
- Trial name
- NCT06876506
- Testing
- Venepuncture, Allergen Specific Immunotherapy
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Rhino Sinusitis
Safety Evaluation of Intranasal Use of DSM 32444 Postbiotic in Humans
Rhinitis is a type of upper respiratory infection with a common nasal pathology especially in Southeast Asia, which is characterized by the presence of one or more of the following symptoms: itchy nose, sneezing, runny nose, and…
- Trial name
- NCT05984004
- Testing
- 0.9% NaCl isotonic saline solution, Bacillus subtilis DSM32444, inactivated
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Huro Biotech Joint Stock Company
Rhinitis, Allergic, Perennial and Seasonal
A Relative Bioavailability Study of Fluticasone Furoate and Levocabastine
This is an open label, randomized, 3-way cross-over, and repeat administration study in healthy male and female subjects. The purpose of the study is to determine the relative bioavailability of Fluticasone Furoate (FF) and…
- Trial name
- NCT01962467
- Testing
- FF/LEV FDC, FF, LEV
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline