Clinical trials: Retroperitoneal Fibrosis
Retroperitoneal Sarcoma, Retroperitoneal Fibrosis
Distinguishing Retroperitoneal Fibrosis and Sarcoma from Other Retroperitoneal Diseases Via Radiomics
A retrospective study utilizing archived CT scans of patients diagnosed with retroperitoneal fibrosis, sarcoma or other malignancies (i.e.
- Trial name
- NCT06741423
- Testing
- Radiomics Algortihm
- Where
- 2 sites in China, Germany
- Volunteers
- 600 people
- Sponsor
- Heidelberg University
Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease
Treatment of IgG4-Related Disease With Revlimid and Rituximab
Among persons with Immunoglobulin G subclass 4 Related Disease (IgG4)-related disease who have persistent or recurrent disease despite standard therapies, does combination therapy with rituximab and revlimid cause a sustained…
- Conditions
- Immunoglobulin G Subclass 4 Related Disease, IgG4-related Disease, Autoimmune Pancreatitis, IgG4-related Sclerosing Cholangitis
- Trial name
- TIGR2 (NCT02705638)
- Testing
- Rituximab, Lenalidomide
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Retroperitoneal Fibrosis
Prednisone Versus Tamoxifen in Idiopathic Retroperitoneal Fibrosis
Idiopathic retroperitoneal fibrosis (IRF) is a rare disease characterised by the presence of a retroperitoneal periaortic fibro-inflammatory tissue which may entrap the ureters and cause renal failure.
- Trial name
- NCT00440349
- Testing
- Tamoxifen, Prednisone
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Parma
Chronic Periaortitis, Intrabony Periodontal Defect
Atorvastatin as an Adjunct to DFDBA in Intrabony Defects
Periodontitis is a major oral health problem which leads to the progressive destruction of periodontal ligament and alveolar bone with pocket formation, recession or both.
- Trial name
- NCT03009097
- Testing
- DFDBA, DFDBA with atorvastatin
- Volunteers
- 26 people
- Sponsor
- Kamineni Institute of Dental Sciences
Idiopathic Retroperitoneal Fibrosis
Early Discontinuation of Steroid Treatment in Negative FDG-PET/CT Patients With Idiopathic Retroperitoneal Fibrosis
Adult patients with a diagnosis of idiopathic retroperitoneal fibrosis Prospective multicentric cohort study Intervention : administration of prednisone during 9 to 21 months at 1mg/kg/day at inclusion.
- Trial name
- METRO (NCT05428826)
- Testing
- Prednisone
- Where
- 15 sites in France
- Volunteers
- 41 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Periaortitis, Tocilizumab Monotherapy
Pilot Study of Tocilizumab Monotherapy for Active Chronic Periaortitis
This is a prospective study to investigate the treatment response of Tocilizumab on patients with active chronic periaortitis (CP).
- Trial name
- NCT05133895
- Testing
- Tocilizumab monotherapy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Peking Union Medical College Hospital
Retroperitoneal Fibrosis
Study of Sirolimus in Idiopathic Retroperitoneal Fibrosis
Retroperitoneal fibrosis refers to a group of diseases characterized by hyperplasia of the fibrosclerotic tissues in the retroperitoneal space, which can compress the surrounding ureters and inferior vena cava and cause serious…
- Trial name
- NCT04047576
- Testing
- Sirolimus, Corticosteroid
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Peking University International Hospital
Retroperitoneal Fibrosis, Autoimmune Pancreatitis
Rituximab in IgG4-RD: A Phase 1-2 Trial
The primary objective of this study is to evaluate the safety and effectiveness of rituximab in IgG4-RD.
- Conditions
- Retroperitoneal Fibrosis, Autoimmune Pancreatitis, Sialadenitis, Pseudotumor
- Trial name
- NCT01584388
- Testing
- Rituximab
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Idiopathic Retroperitoneal Fibrosis
A Prospective Study of Cyclophosphamide Treatment for Idiopathic Retroperitoneal Fibrosis
This prospective, interventional, controlled study is aimed to evaluate the efficacy and safety of cyclophosphamide in the treatment of idiopathic retroperitoneal fibrosis, which refers to the chronic nonspecific inflammation of…
- Trial name
- IRPF (NCT04762810)
- Testing
- Cyclophosphamide and glucocorticoids, Glucocorticoids
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Immunoglobulin G4 Related Sclerosing Disease
Leflunomide for Maintenance of Remission in IgG4 Related Disease
The study has been designed as a 12-month, open-label, randomized, controlled study comparing the use of prednisone mono-therapy and prednisone and leflunomide combination therapy in treating patients with IgG4-related disease.
- Trial name
- NCT02703194
- Testing
- Prednisone, Leflunomide
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Chinese PLA General Hospital
Idiopathic Retroperitoneal Fibrosis
A Prospective Cohort Study of IRPF in China
This is a cohort study to investigate the disease course and treatment response of patients with idiopathic retroperitoneal fibrosis（IRPF）.
- Trial name
- IRPF (NCT04312854)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Idiopathic Retroperitoneal Fibrosis
National Registry of IRPF in China
The aim of this study is to establish a nation-wide cohort study of idiopathic retroperitoneal fibrosis (IRPF) in China. Methods: All the patients fulfilling diagnostic criteria of IRPF would be enrolled from multi-centers around…
- Trial name
- NCT04314323
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Idiopathic Aortitis, Retroperitoneal Fibrosis
Aortitis and Retroperitoneal Fibrosis: Evaluation of Diagnostic Criteria
Inflammatory aortitis probably represents a heterogeneous group, and the clinical experience accumulated over the last ten years, shared by the experts of the subject, is that the initial clinical, biological or radiological…
- Trial name
- NCT03133949
- Testing
- Establish the clinical, biological and radiological characteristics of patients
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Idiopathic Retroperitoneal Fibrosis
A Prospective Study of Tocilizumab in the Treatment of Idiopathic Retroperitoneal Fibrosis
This is a prospective study to investigate the treatment response of Tocilizumab on patients with idiopathic retroperitoneal fibrosis（IRPF）. Methods: All the patients fulfilling diagnostic criteria of IRPF would be enrolled.
- Trial name
- NCT04762784
- Testing
- Tocilizumab, Glucocorticoids
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Idiopathic Retroperitoneal Fibrosis, Perianeurysmal Retroperitoneal Fibrosis
Methotrexate as a Steroid-sparing Agent in Idiopathic Retroperitoneal Fibrosis: a Randomised, Multicenter Trial
Chronic periaortitis is a clinico-pathological entity encompassing idiopathic retroperitoneal fibrosis and perianeurysmal retroperitoneal fibrosis.
- Conditions
- Idiopathic Retroperitoneal Fibrosis, Perianeurysmal Retroperitoneal Fibrosis, Chronic Periaortitis
- Trial name
- FIPREDEX (NCT01240850)
- Testing
- Methotrexate+Prednisone, Prednisone
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Parma
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association