Clinical trials: Retinal Detachment Rhegmatogenous
Retinal Detachment
Comparison High-density Silicone Oils in Retinal Detachment
The purpose of the study is to compare the safety, intraocular adverse effects and the anatomic and functional outcome with two endotamponade silicone oil after a 3-month in complex inferior retinal re-detachments.
- Trial name
- NCT00403702
- Testing
- Oxane HD [oil-RMN3-mixture], Densiron [(F6H8)
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Rhegmatogenous Retinal Detachment
Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment
The purpose of this research study is to compare the outcomes of pneumatic retinopexy with the outcomes of vitrectomy (with or without scleral buckle) for the management of retinal detachment, in terms of anatomical success…
- Trial name
- NCT01639209
- Testing
- Vitrectomy, Pneumatic retinopexy
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- Unity Health Toronto
Retinal Detachment With Multiple Breaks, Unspecified Eye, Proliferative Vitreoretinopathy
Intravitreal Aflibercept for the Prevention of Proliferative Vitreoretinopathy Following Retinal Detachment Repair
The primary objective of the study is to determine if serial intravitreal aflibercept injections (IAI) improve the single surgery anatomic success rate following surgical repair of primary, macula involving rhegmatogenous retinal…
- Trial name
- PREVENT-PVR (NCT04580147)
- Testing
- Intravitreal aflibercept injection
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- M. Ali Khan, MD
Rhegmatogenous Retinal Detachment
Comparative Study Between Three Different Techniques in Drainage of SRF During PPV in RRD
The study will investigate and compare the three techniques in drainage of subretinal fluid in patients with macula off RRD: namely using the original break, performing a posterior drainage retinotomy and using PFC with drainage…
- Trial name
- NCT06324305
- Testing
- Pars plana vitrectomy (PPV) and drainage of subretinal fluid
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Retinal Detachment, Vitrectomy
Functional and Morphological Results of Rhegmatogenous Retinal Detachment Treated With Vitrectomy
To examine morphological and functional results after pars plana vitrectomy (PPV) with SF6 gas tamponade due to macula-on and macula-off rhegmatogenous retinal detachment (RRD) during six months of the follow-up.
- Trial name
- NCT03902795
- Testing
- Microperimetry, M-charts
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Lublin
Pediatric Rhegmatogenous Retinal Detachment
Outcomes of Vitrectomy in Pediatric Retinal Detachment With Proliferative Vitreoretinopathy
The aim of this study is to report outcomes of pars plana vitrectomy (PPV) in pediatric retinal detachment (RD) accompanied with proliferative vitreoretinopathy (PVR) as well as complications and factors influencing the final…
- Trial name
- NCT03208205
- Testing
- vitrectomy
- Where
- Poland
- Volunteers
- 14 people
- Sponsor
- Medical University of Lublin
Proliferative Vitreoretinopathy, Rhegmatogenous Retinal Detachment
Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial
I. Title Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial Today's Date: September 18, 2023 II.
- Trial name
- FIXER (NCT06541574)
- Testing
- Methotrexate Injection, Methotrexate Infusion
- Where
- United States
- Volunteers
- 860 people
- Sponsor
- Cincinnati Eye Institute, Southwest Ohio
Rhegmatogenous Retinal Detachment
Retinal Detachment - Demographic and Clinical Survey
Background: Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year.
- Trial name
- NCT01845571
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Rhegmatogenous Retinal Detachment
Perfluorocarbon Liquid vs. Posterior Retinotomy During Pars-plana Vitrectomy for Rhegmatogenous Retinal Detachment
Purpose To evaluate the outcomes of perfluorocarbon liquid (PFCL) versus posterior retinotomy (PR) during Pars plana vitrectomy (PPV) for Rhegmatogenous retinal detachment (RRD), focusing on anatomical success, visual acuity…
- Trial name
- NCT06919211
- Testing
- Perfluorocarbon Liquid vs. Posterior Retinotomy during Pars-plana Vitrectomy for The Surgical Repair of Rhegmatogenous Retinal Detachment
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Benha University
Rhegmatogenous Retinal Detachment
Effect of Silicon Oil on Retinal Electrical Functions Using Multifocal Electroretinogram
Retinal detachment is one of the leading causes for permanent vision loss.Incidence of Rheugmatogenous Retinal Detachment (RRD) about 10.5 people per 100,000 population pars plana vitrectomy is the most popular and effective…
- Trial name
- SO/RRD/mfERG (NCT07609628)
- Testing
- Multi focal electroretinogram
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Retinal Redetachment After Silicone Oil Removal
Retinal Redetachment After Silicone Oil Removal : a Risk Factor Analysis
To report the rate of retinal redetachment after silicone oil removal (SOR) following rhegmatogenous retinal detachment (RRD) surgery and to determine potential risk factors
- Trial name
- NCT05647928
- Testing
- no intervention
- Where
- France
- Volunteers
- 307 people
- Sponsor
- Central Hospital, Nancy, France
Rhegmatogenous Retinal Detachment With Grade C Proliferative Vitreoretinopathy
Comparison of Visual Outcomes of Pars Plana Vitrectomy With and Without Injection Clexane for Rhegmatogenous Retinal Detachment Proliferative Vitreoretinopathy
This interventional prospective study was conducted in the Department of Ophthalmology at Lahore General Hospital, Lahore. The study included 60 male and female patients aged 18-65 years who had rhegmatogenous retinal detachment…
- Trial name
- NCT07787377
- Testing
- Enoxaparin Sodium, Pars Plana Vitrectomy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Rhegmatogenous Retinal Detachment
Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment
26 patients presenting a rhegmatogenous retinal detachment with more than 4 days of duration will be prospectively included. A single dose of ursodeoxycholic acid will be administered orally before surgery at different…
- Trial name
- UDCA-RD (NCT02841306)
- Testing
- Ursodeoxycholic Acid
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Francine Behar-Cohen
Rhegmatogenous Retinal Detachment - Macula Off
A Study to Evaluate the Safety and Tolerability of ONL1204 in Patients With Macula-off, Rhegmatogenous Retinal Detachment
The purpose of this study is to evaluate the safety and tolerability of ONL1204 in participants with Macula-off, Rhegmatogenous Retinal Detachment (RRD).
- Trial name
- NCT03780972
- Testing
- ONL1204, Intravitreal Injection, Collection of ocular fluids
- Where
- 4 sites in Australia
- Volunteers
- 14 people
- Sponsor
- ONL Therapeutics
Retinal Detachment
REtinal Detachment Outcomes Study
Background: Few large randomized controlled trials provide strong evidence to guide surgical repair of primary rhegmatogenous retinal detachment (RRD) repair.
- Trial name
- REDOS (NCT05863312)
- Testing
- Pars plana vitrectomy, Pars plana vitrectomy with scleral buckle, Sulfur hexafluoride gas tamponade
- Where
- Canada
- Volunteers
- 560 people
- Sponsor
- CHU de Quebec-Universite Laval
Retinal Detachment
Scleral Self-indentation Chandelier-assisted Peripheral Vitrectomy Under Air Rhegmatogenous Retinal Detachment.
The investigators compared the incidence of trimming-induced retinal breaks, retinal redetachment rate, and final LogMAR BCVA; between scleral self-indentation and non-indentation during chandelier-assisted peripheral vitrectomy…
- Trial name
- NCT03218371
- Testing
- chandelier-assisted peripheral vitrectomy under air
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Dar El Oyoun Hospital
Rhegmatogenous Retinal Detachment, Toxic Effect of Silicone
The Influence of Silicone Oil on Nerve Fiber Layer Thickness After Pars Plana Vitrectomy
The aim of the study is to evaluate the influence of silicone oil on thickness of the retinal nerve fiber layer by using optical coherence tomography (OCT) in patients following pars plana vitrectomy.
- Conditions
- Rhegmatogenous Retinal Detachment, Toxic Effect of Silicone, Glaucoma Due to Silicon Oil
- Trial name
- NCT01255306
- Testing
- Optical coherence tomography, Local medical treatment of raised intraocular pressure
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Sestre Milosrdnice
Proliferative Vitreoretinopathy
Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients
Rhegmatogenous retinal detachment (RRD) is a sight-threatening condition. Children with RRD usually present late with clinical features of longstanding RRD, specifically a serious condition named: proliferative vitreoretinopathy…
- Trial name
- SIGHT (NCT04830878)
- Testing
- Methotrexate
- Where
- United States
- Sponsor
- Stanford University
Retinal Displacement After Retinal Detachment Surgery
Influence of Perfluorocarbon Liquid (LIQUID) During Pars Plana Vitrectomy on Retinal Vessel Displacement in Primary Macula-involving Rhegmatogenous Retinal Detachment
Rhegmatogenous retinal detachment (RRD) is an acute, sight threatening condition, with an incidence of approximately 10 per 100,000 people.
- Trial name
- LIQUID (NCT07027098)
- Testing
- Perflurocarbon liquid, Without Perflurocarbon liquid
- Where
- United Kingdom
- Volunteers
- 292 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Retinal Detachment Rhegmatogenous, Proliferative Vitreoretinopathy
Intravitreal Topotecan for Prevention or Treatment of Proliferative Vitreoretinopathy in Retinal Detachment
Intravitreal topotecan exhibits strong anti-inflammatory, anti-proliferative, and anti-fibrotic properties, making it a promising option for preventing and treating proliferative vitreoretinopathy in rhegmatogenous retinal…
- Trial name
- TOPO-PT (NCT06818721)
- Testing
- Intravitreal topotecan, Retinal detachment surgery
- Where
- 2 sites in Canada
- Volunteers
- 394 people
- Sponsor
- Unity Health Toronto