Clinical trials: Retinal Detachment
Retinal Detachment Rhegmatogenous, ILM Peeling
1ry Versus 2ry ILM Peeling in RD
Patients with uncomplicated rhegmatogenous retinal detachment will be recruited. All eyes will underwent 23G PPV with silicon oil tamponade. The eyes will be classified into two groups according to the timing of ILM peeling.
- Trial name
- NCT07346560
- Testing
- Primary ILM peeling, Secondary ILM peeling
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR)
Proteomic Biomarker Identification in Age-Related Macular Degeneration, Diabetic Retinopathy and Retinal Detachment
This prospective interventional translational study aims to identify and validate protein biomarkers associated with major ophthalmological diseases, including age-related macular degeneration, diabetic retinopathy (DR), and…
- Conditions
- Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), Retinal Detachment
- Trial name
- PRO Project (NCT07500324)
- Testing
- Biological Sample Collection
- Where
- Italy
- Volunteers
- 260 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy
Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment
This study has two main objectives. The first objective is to study the pharmacokinetics of topical netarsudil administration in the posterior segment of the eye, where netarsudil must exert its effect in order to prevent…
- Trial name
- NCT06033703
- Testing
- Netarsudil Ophthalmic
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Retinal Detachment Multiple Breaks
Redetachment Under Densiron for RD Multiple Breaks
Densiron is used as a tamponading agent for inferior retinal detachment with inferior retinal breaks However, data about the use of Densiron -68 for RRD with multiple retinal breaks; especially if involving both superior and…
- Trial name
- Densiron (NCT05716971)
- Testing
- Densiron-68 (heavy silicone oil) tamponade for retinal detachment
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Dar El Oyoun Hospital
Macular Disease, Rhegmatogenous Retinal Detachment
Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
Based on the progress of cataract surgery, intraocular lens development, vitreoretinal surgery and anesthesia technology in recent years, the purpose of this study is to develop a new type of more accurate and minimally invasive…
- Conditions
- Macular Disease, Rhegmatogenous Retinal Detachment, Epiretinal Membrane, Cataract
- Trial name
- NCT05588037
- Testing
- FLACS +PPV+IOL + air, FLACS +PPV+IOL + epiretinal membrane peeling + Ozurdex, FLACS + PPV+IOL + internal limiting membrane peeling + air
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Retinal Detachment
The Influence of Postoperative Postures on Persistent Sub-foveal Fluid After Scleral Buckle Surgery
The purpose of this study is to evaluate whether postoperative postures influence persistent sub-foveal fluid after scleral buckle surgery
- Trial name
- NCT02294708
- Testing
- postoperative postures
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Proliferative Diabetic Retinopathy, Tractional Retinal Detachment
Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy
To evaluate efficacy of different intravitreal Conbercept injection therapy in the treatment of severe proliferative diabetic retinopathy.
- Trial name
- NCT02816710
- Testing
- Conbercept
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Ruijin Hospital
Postoperative Pain, Retinal Detachment
Postoperative Pain After Vitreoretinal Surgery
Postoperative pain (POP) is frequently underestimated in general and little data are available particularly for POP after vitreoretinal surgery (VRS).
- Trial name
- NCT03538847
- Testing
- Numerical rating scale
- Volunteers
- 800 people
- Sponsor
- University of Florence
Retinal Detachment
Use of Ocular Point of Care Ultrasound in Diagnosing Retinal Detachment in the Emergency Department
The study is collecting data along with other academic institutions regarding the accuracy of ocular ultrasound in diagnosing retinal detachment.
- Trial name
- RDOcularUS (NCT03106025)
- Testing
- Ultrasound, Ophthalmology Assessment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Loma Linda University
Retinal Detachment
Correlation of Metamorphopsia and Aniseikonia to Retinal Shift Following Retinal Detachment Surgery
Individuals operated for rhegmatogenous retinal detachment will be prospectively evaluated for postoperative retinal shift. Fundus autofluorescence will be used to evaluate retinal shift that will be correlated to visual acuity…
- Trial name
- NCT03187613
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Helse Stavanger HF
Retinal Pigment Epithelial Detachment With Vascularization, Age Related Macular Degeneration
Iray for Vascularized Pigment Epithelial Detachment (VPED) Secondary to Age Related Macular Degeneration
This is a pilot, single-center, interventional clinical trial in which subjects will receive 16 Gy of IRay treatment and Lucentis, followed by Lucentis treatment as needed.
- Trial name
- NCT01521819
- Testing
- Iray, Lucentis
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Oraya Therapeutics, Inc.
Retinal Detachment, Macular Hole
Head Position Monitoring After Pars Planar Vitrectomy
In ophthalmic surgical practice, particularly for treating retinal detachment and macular hole disorders, vitrectomy procedures are routinely performed to remove the vitreous body followed by the injection of tamponade agents…
- Trial name
- HPMPPV (NCT06985030)
- Testing
- gyroscope embedded eye-sheild
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Spontaneous Vitreous Hemorrhage, Retinal Break
Early VItrectomy in DENse Spontaneous Vitreous HEmorrhage
The aim of the protocol is to compare the ocular outcomes after spontaneous vitreous hemorrhage treated with an early vitrectomy versus ultrasound monitoring with late vitrectomy.
- Conditions
- Spontaneous Vitreous Hemorrhage, Retinal Break, Retinal Detachment
- Trial name
- EVIDENSE (NCT04676256)
- Testing
- Early vitrectomy
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Retinal Detachment, Metamorphopsia
Retinal Displacement Rates in Pneumatic Retinopexy Versus Pars Plana Vitrectomy For Primary Retinal Detachment
Patients may experience metamorphopsia, or image distortion, after having vitrectomy to repair their rhegmatogenous retinal detachments (RRDs) especially those with a detached macula.
- Trial name
- REVEAL (NCT04158622)
- Testing
- PnR + laser/cryotherapy, PPV + laser/cryotherapy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Unity Health Toronto
Optic Disc Structural Anomaly, Maculopathy
Surgical Management of Optic Disc Pit Maculaopathy
To evaluate the anatomical and functional results of pars plana vitrectomy (PPV) combined with internal limiting membrane (ILM) peeling, endolaser photocoagulation and gas tamponade in management of optic disc pit (ODP)…
- Trial name
- NCT03185936
- Testing
- pars plana vitrectomy with internal limiting membrane (ILM) peeling
- Volunteers
- 9 people
- Sponsor
- Minia University
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
Comparing primary PPV with 360° endolaser photocoagulation with primary PPV with an encircling band for patients with RRDs.
- Conditions
- Rhegmatogenous Retinal Detachment, Primary Vitrectomy, Encircling Band, Endolaser Treatment
- Trial name
- NCT00757536
- Testing
- Encircling Band, Endolaser Photocoagulation
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Retina Detachment, Eye Injuries
Multi-center Clinical Observation of FCVB in Guangdong Province
This study provides further theoretical guidance for clinical application of FCVB through observing and collecting various indicators before and after surgical treatment of the FCVB in the real world.
- Conditions
- Retina Detachment, Eye Injuries, Eye Atrophy, Silicone Emulsion
- Trial name
- NCT03908515
- Testing
- Foldable Capsular Vitreous Body (FCVB)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Vitreoretinopathy, Coats' Disease
DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia
The Tender Study is a prospective, open-label, single-center, randomized, investigator-initiated clinical study seeks to investigate the safety and efficacy of the DEXTENZA insert in pediatric patients following retinal surgery…
- Conditions
- Vitreoretinopathy, Coats' Disease, Exudative Retinopathy, Lattice Degeneration
- Trial name
- NCT05620901
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Pred Forte
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lejla Vajzovic, MD, FASRS
Retinal Detachment, Proliferative Vitreoretinopathy
Postoperative Pain Control Following Vitreoretinal Surgery
The aim of this study is to evaluate if patients receiving a steroid (triamcinolone acetonide) combined with local anesthesia and antibiotic following retina surgery have better postoperative pain control those receiving local…
- Conditions
- Retinal Detachment, Proliferative Vitreoretinopathy, Retinoschisis
- Trial name
- NCT01995045
- Testing
- Triamcinolone, Bupivicaine Hydrochloride
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Rhegmatogenous Retinal Detachment
Macular Function After Scleral Buckle
Assess recovery of macula function after successful scleral buckling surgery for rhegmatogenous retinal detachment by using the multifocal ERG in the postoperative period i.e. recovery of functional integrity 2.
- Trial name
- NCT00345007
- Testing
- Scleral buckling
- Where
- Singapore
- Volunteers
- 27 people
- Sponsor
- Singapore National Eye Centre