Clinical trials: Resuscitation
Advanced Cardiac Life Support Education
Effects of Two-Tier Test-Based Virtual Reality Instruction on ACLS Outcomes Among Clinical Nurses
This study aims to evaluate the effects of two-tier test-based virtual reality (VR) instruction on Advanced Cardiac Life Support (ACLS) learning outcomes among clinical nurses.
- Trial name
- NCT07862322
- Testing
- Two-Tier Test-Based Virtual Reality Instruction, Traditional Interactive Virtual Reality Instruction
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taoyuan General Hospital
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Septic Shock, Sepsis
Core-to-Big-Toe Temperature Gradient as a Marker of Peripheral Perfusion in Adult Patients With Septic Shock
Septic shock is a life-threatening condition caused by severe infection that leads to dangerously low blood pressure and impaired blood flow to body tissues and organs.
- Trial name
- NCT07871305
- Volunteers
- 54 people
- Sponsor
- Assiut University
Cardiopulmonary Resuscitation, Cardiac Arrest
Physical Workload Identify in Chest Compression Position Using Surface Electromyogram
The chest compression depth decreases over time after starting continuous chest compression due to the rescuers' fatigue. The investigators hypothesized that the frequency parameters from surface electromyogram from each muscle…
- Trial name
- NCT02088879
- Testing
- chest compression with kneeling position, chest compression with standing position
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Respiratory Distress
Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
The stomach of the newborn baby is often emptied soon after birth to prevent breathing problems (respiratory distress). Babies born with meconium-stained amniotic fluid and those with increased secretions associated with birth by…
- Trial name
- NCT00729989
- Testing
- Gastric suctioning
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Stevens
Efficacy and Safety of Xenon Inhalation, Successful Cardiopulmonary Resuscitation
Xenon and Therapeutical Hypothermia After Successful Cardiopulmonary Resuscitation
In this clinical trial will be checked, whether 2 hour ventilation with xenon has neuroprotective effects in patients with out of hospital cardiac arrest and successful cardiopulmonary resuscitation
- Conditions
- Efficacy and Safety of Xenon Inhalation, Successful Cardiopulmonary Resuscitation, Addition to Therapeutical Hypothermia
- Trial name
- 10-015 (NCT01262729)
- Testing
- therapeutical hypothermia, Xenon Inhalation
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- RWTH Aachen University
Basic Cardiac Life Support, Cardiopulmonary Resuscitation
The Effect of T-CPR on the Quality of CPR and AED Use
The purpose of the study is to examine the effect of telephone assistance and standardized basic life support courses on the quality of cardiopulmonary resuscitation (CPR) and the use of automated external defibrillator (AED).
- Trial name
- NCT03690102
- Testing
- T-CPR, ERC standardized BLS course
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Cardiac Arrest With Successful Resuscitation, Hypoxia, Brain
Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation
The STEPCARE-trial is a 2x2x2 randomised trial studying patients who have been resuscitated from cardiac arrest and who are comatose.
- Trial name
- STEPCARE (NCT05564754)
- Testing
- Feedback-controlled temperature device, High MAP, Deep sedation
- Where
- 56 sites in Australia, Belgium and 13 more
- Volunteers
- 3,500 people
- Sponsor
- Region Skane
Infant Showing No Response to Resuscitation
MedNav: Improving Neonatal Life Support (NLS)
This study was designed to evaluate if MedNav impacts the ability of novice resuscitators to perform Neonatal Life Support (NLS) in the simulated environment, and if this ability is maintained after a 7 week period.
- Trial name
- NCT02932683
- Testing
- MedNav
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Wounds and Injuries
Polytrauma and Resuscitation Impact on Innate Immunity
Major trauma can lead to a dysregulated response to secondary infection. Severe injuries are accompanied by pro- and antiinflammatory changes that affect both adaptive and innate immunity.
- Trial name
- PRIME (NCT06314841)
- Where
- 3 sites in Austria
- Volunteers
- 62 people
- Sponsor
- Ludwig Boltzmann Gesellschaft
COVID-19 (Coronavirus Disease 2019)
Thrombohemorrhagic Complications of COVID-19
The nature of the planned study: The topic is of an applied nature and is aimed at improving the results of comprehensive treatment of patients with COVID-19, the course of whose disease was complicated by thrombotic or…
- Trial name
- NCT06223945
- Testing
- Prevention algorithm
- Where
- Russia
- Volunteers
- 1 people
- Sponsor
- Volgograd State Medical University
Acute Kidney Injury Due to Sepsis
Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group
The impact of early de-resuscitation with furosemide on patients with sepsis-related acute kidney injury using pNGAL as the parameter of acute kidney injury.
- Trial name
- NCT05939245
- Testing
- Furosemide Injection
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Sepsis
Mechanistic Inflammatory Sub-study Embedded Within the Albumin vs Balanced Crystalloid Trial
MIS-ABC Sepsis is a sub-study looking to understand how the immune response in patients with infection changes during the early stages of the illness, as well as after intravenous fluid treatment.
- Trial name
- MIS-ABC Sepsis (NCT04963569)
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Edinburgh
Atrial Fibrillation, Assessment of Serious Advers Events
Prospective Registration and Assessment of Serious Adverse Events Within the AFNET
Prospective registration and independent assessment of SAE associated with atrial fibrillation such as thromboembolic events, and other cardiac and noncardiac complications by a Critical Event Committee.
- Conditions
- Atrial Fibrillation, Assessment of Serious Advers Events, Thromboembolic and Bleeding Complications, Complications of Antiarrhythmic Drugs or Invasive Procedures
- Trial name
- AFNET A7 (NCT01678456)
- Where
- Germany
- Volunteers
- 13,000 people
- Sponsor
- Atrial Fibrillation Network
Congenital Diaphragmatic Hernia
Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia
This study aims to measure the cardio-respiratory physiological consequences of initiating resuscitation during placental transfusion (PT) with an intact umbilical cord in infants with congenital diaphragmatic hernia (CDH).
- Trial name
- INSPIRE-CDH (NCT03094039)
- Testing
- Ventilatory support while attached to the cord, Immediate cord clamping
- Where
- Canada
- Sponsor
- University of Alberta
Fetal Distress
Effect of Umbilical Cord Milking on Transition of Preterm Babies During Resuscitation
Investigators will evaluate if milking of umbilical cord in preterm babies will improve transition during resuscitation or not
- Trial name
- NCT03859037
- Testing
- Umbilical cord milking
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation
Clinical Application of Low-Field Magnetic Resonance Imaging in Patients on Extracorporeal Cardiopulmonary Resuscitation
Timely identification of acute brain injury (ABI) patterns in patients with extracorporeal cardiopulmonary resuscitation (ECPR) is essential for prognostic assessment and optimization of clinical management, particularly…
- Conditions
- Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation, Acute Brain Injury
- Trial name
- NCT07526701
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Capital Medical University
CPR Guidelines
Flowchart-Assisted Resuscitation. Standard CPR vs. Chest Compressions Only: What Happened to the Quality?
ABSTRACT Background: More than two thirds of sudden cardiac arrests are witnessed by bystanders. Bystander cardiopulmonary resuscitation (CPR) doubles survival from cardiac arrest.
- Trial name
- NCT02438527
- Testing
- Chart for CPR guidance
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Outcome From Traumatic Cardiac Arrest
This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest.
- Trial name
- NCT05294575
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Premature Birth
Prophylactic DR-CPAP on Late Preterm Infants Born by C-section: an RCT
A Pragmatic Randomized Controlled Pilot Trial to Evaluate the Impact of Early Prophylactic Continuous Positive Airway Pressure with or without Supplemental Oxygen in Spontaneously Breathing Late Preterm Newborn Infants Born by…
- Trial name
- PLANT (NCT05204719)
- Testing
- Prophylactic Delivery Room Continuous Positive Airway Pressure
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma