Clinical trials: Respiratory Sounds
eHealth, Telemedicine
Luchtbrug Junior: the Next Step
Rationale: The introduction of e-health in the monitoring and management of patients with chronic conditions can be beneficial and efficient.
- Conditions
- eHealth, Telemedicine, Wheezing
- Trial name
- NCT05682664
- Testing
- Luchtbrug Junior (online monitoring), Usual care
- Volunteers
- 270 people
- Sponsor
- Radboud University Medical Center
Asthma, Wheeze
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
The study will ascertain the ability of preschool lung function tests to distinguish healthy children from those with wheeze, and to differentiate phenotypes of wheezy children (high and low risk for asthma as defined by API) in…
- Conditions
- Asthma, Wheeze, Obstructive Sleep Apnea, Food Allergy
- Trial name
- WheezyER (NCT02743663)
- Testing
- Bronchodilator response, Allergy Skin Test, Multiple-Breath Washout
- Where
- Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Sleep Apnea
Validation of Sleep Apnea Diagnosis Device
Obstructive sleep apnea (OSA) is common and largely underdiagnosed disease. The standard method for the diagnosis of OSA is a complete night polysomnography (PSG). Simple methods for OSA diagnosis are necessary.
- Trial name
- NCT03526133
- Testing
- Polysomnography (PSG) and wireless sensor Oxistar
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Asthma, Wheezing
Oral Bacterial Extract for the Prevention of Wheezing Lower Respiratory Tract Illness
The primary objective of this study is to evaluate if Broncho-Vaxom® given to high risk infants for 10 days, monthly, for two consecutive years can increase time to occurrence of the first episode of wheezing lower respiratory…
- Trial name
- ORBEX (NCT02148796)
- Testing
- Broncho-Vaxom (BV)
- Where
- 11 sites in United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Wheezing, Allergy
Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy
The goal of this study is to identify a vitamin D supplementation strategy that best promotes the lung, immune, and overall health of black infants born preterm (28-36 weeks gestational age).
- Trial name
- D-Wheeze (NCT01601847)
- Testing
- Cholecalciferol
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Case Western Reserve University
Wheezing
Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children
We can not predict which wheezing child younger than 3 years of age benefits from systemic glucocorticoid and which one does not.
- Trial name
- VINKU (NCT00494624)
- Testing
- prednisolone
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- University of Turku
Respiration Disorders, Respiratory Disease
The Gut-Lung Axis and Respiratory Illness in Children
The goal of this single-centre observational study conducted at the Royal Hospital for Children in Glasgow, Scotland, is to employ a multi-omics approach to investigate the "gut-lung axis" in health and disease.
- Conditions
- Respiration Disorders, Respiratory Disease, Asthma in Children, Wheezing
- Trial name
- NCT06271213
- Testing
- observational only - no interventions as part of study
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Snoring, Pharyngeal Collapse
Rehabilitative Approaches: Myofunctional Therapy and Retropalatal Narrowing and Snoring
Sleep is an important activity and snoring is the most often reported complaint. Snoring is also very common in the general population.
- Trial name
- NCT06186687
- Testing
- Myofunctional therapy exercise
- Where
- Indonesia
- Volunteers
- 17 people
- Sponsor
- Universitas Padjadjaran
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Snoring
Upper Airway Training for Treatment of Snoring
The objective of this study is to reduce the incidence or intensity of snoring in a patient population of known simple snorers without sleep apnea using smartphone based application which allows participants to play voice…
- Trial name
- NCT03264963
- Testing
- Smart phone game play, Control
- Volunteers
- 32 people
- Sponsor
- University of Minnesota
Stridor
Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children
The study aims to analyze and compare the clinical effects of using inhaled budesonide or intravenous dexamethasone in the treatment of postextubation stridor on children admitted to the pediatric intensive care units at Hospital…
- Trial name
- BUDEXA (NCT02056379)
- Testing
- Budesonide, Dexamethasone
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Israelita Albert Einstein
Acute Respiratory Tract Infection
Differentiation of Upper and Lower Respiratory Tract Infections Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate upper and lower respiratory tract infections (URTI and LRTI)
- Trial name
- NCT05175612
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 400 people
- Sponsor
- Healthy Networks
Respiratory Tract Infections, Wheezing
A 24 Month Observational Study of Infants 3-24 Months, Who Suffer an Acute Episode of Respiratory Infection and Wheezing Illness
This study will identify infants between the age of 3 and 24 months of age who are experiencing one of their first acute respiratory infections with confirmed wheezing.
- Trial name
- BIOPA (NCT03741322)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Wheezing, Asthma in Children
Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study
The goal of this clinical trial is to compare soy isoflavones to placebo in children who at risk of asthma and have a genetic variation which results in them making more of a pro-inflammatory protein, plasminogen activator…
- Trial name
- SIRA (NCT05667701)
- Testing
- Soy isoflavone
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rajesh Kumar
Atopy, Atopic Dermatitis Eczema
Breast Milk: Influence of the Micro-transcriptome Profile on Atopy in Children Over Time
This is an observational cohort study of 221 breast-feeding mother-infant dyads delivered at term. The goal of the study is to investigate whether levels of immune-related microRNAs (miRNAs) in maternal breast milk (MBM)…
- Conditions
- Atopy, Atopic Dermatitis Eczema, Wheezing, Food Allergy in Infants
- Trial name
- IMPACT (NCT04017520)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Snoring
Pretreatment Assessment of Oropharynx Ans Soft Palate Radiofrequency Surgery - a Multi-center Study
Interstitial radiofrequency (RF) surgery of the soft palate (SP) is an established option in the treatment of habitual snoring. The decision making process in the management of habitual snoring would benefit from diagnostic…
- Trial name
- NCT01223859
- Testing
- Interstitial soft palate surgery
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Asthma, Obesity
Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics (Glitz Asthma)
Asthmatics who are significantly overweight tend to have more severe symptoms, more flare ups, and are more likely to have poorly-controlled asthma when compared to other asthmatics.
- Trial name
- GLITZ (NCT00787644)
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Vermont
Asthma, Acute Asthma
Nebulized Budesonide for Children Who Are Hospitalized for Acute Wheezing
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in children who have hospitalized for acute wheezing.
- Trial name
- NCT00733473
- Testing
- Budesonide 0.5 mg/ml nebules, % 0.9 Saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kecioren Education and Training Hospital
Obstructive Sleep Disordered Breathing
Prediction of Tongue Base Obstruction During Sleep
This study investigates the hypothesis that, in children, tongue motor functions can predict both the anatomical site and the degree of upper airway obstruction contributing to obstructive sleep-disordered breathing.
- Trial name
- PTOS (NCT06792045)
- Testing
- Physiotherapist assessment, ENT assessment, Drug-Induced Sleep Endoscopy
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Université Catholique de Louvain
Snoring, Obstructive Sleep Apnea
TranQuill™ Sling Snoreplasty for Snoring and Mild Obstructive Sleep Apnea:
The purpose of this study is to assess the safety and effectiveness of TranQuillTM Sling (a suture or thread used in surgery that is knotless) in snoreplasty (surgery procedure) for the treatment of snoring and mild OSA in adult…
- Trial name
- NCT02364518
- Testing
- Snoreplasty
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina