Clinical trials: Respiratory Physiology
Balanced; Rearrangement, Respiratory Function Test
The Effect of Lycra Garment on Spastic Diplegic Cerebral Palsy Individuals With Scoliosis
The primary aim of this study was to investigate the effects of lycra clothing on balance and respiratory functions in individuals with cerebral palsy with scoliosis, and the secondary aim was to investigate the effects of lycra…
- Trial name
- NCT06295991
- Testing
- Lycra garment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Mild-to-Moderate COVID-19
A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function
This exploratory, open-label clinical study aims to explore the physiologic effects of KB109, a novel glycan, on adult patients with COVID-19 illness on gut microbiota structure and function in the outpatient setting.
- Trial name
- NCT04486482
- Testing
- KB109 + Self Supportive Care (SSC), Self Supportive Care (SSC) Alone
- Where
- 12 sites in United States
- Volunteers
- 49 people
- Sponsor
- Kaleido Biosciences
Asthma
Impact of Metabolic Dysfunction and Mucus Plugging on Asthma Physiology
This is a single-center study of 80 subjects with asthma including those with obesity and metabolic dysfunction (MD), those with obesity and without metabolic dysfunction, those with severe asthma and mucus plugging and those…
- Trial name
- IMAP (NCT05757583)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Francisco
Occupational Exposure
Occupational Exposure to Dust and the Relationship With the Respiratory Symptoms, Lung Function Among Construction Workers of the University of Malaysia Sabah (UMS)
Background The respiratory tract often becomes the site of injury from occupational exposure. All construction sites generate high levels of dust, typically from concrete, silica, asbestos, cement, wood, stone, sand and…
- Trial name
- NCT05226273
- Testing
- no intervention
- Where
- Malaysia
- Volunteers
- 152 people
- Sponsor
- Universiti Malaysia Sabah
Obstructive Sleep Apnea
Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not…
- Trial name
- NCT00757796
- Volunteers
- 80 people
- Sponsor
- Assaf-Harofeh Medical Center
COVID-19
TDCS Stimulation After Covid-19 Infection
In this study, the effects of bilateral stimulation of the dorsolateral prefrontal cortex (DLPFC) with active tDCS (transcranial direct stimulation/transcranial direct stimulation) on neurocognitive (memory and executive)…
- Trial name
- NCT06183424
- Testing
- Transcranial Direct Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Lung Cancer
Early Detection of Lung Cancer in a High-Risk Population Defined by PFT, Biomarkers, and CT Scanning
Lung cancer is the number one cancer killer in Kentucky and has a very high incidence within the 5th Congressional District of Kentucky (110.8 cases per 100,000 in period 1996-2000).
- Trial name
- NCT00596310
- Testing
- CT
- Where
- 4 sites in United States
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Susanne Arnold
COPD, Walking, Difficulty
Effect of Face Masks on Pulmonary Function in Patients With COPD
Given the heightened vulnerability of COPD patients to severe illness upon SARS-CoV-2 infection, precautions like mask-wearing are deemed crucial.
- Trial name
- NCT05742880
- Testing
- 6 Minute Walking Test, Blood gas analysis, Wearing a Surgical Facemask
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
COVID-19, Rehabilitation
Evaluation of Effectiveness of Proprietary Rehabilitation Program in Patients After COVID-19 Infection
The aim of the study is to evaluate the influence of 6 week physical training and respiratory rehabilitation performed in outpatients rehabilitation clinic on quality of life, symptoms, physical endurance, mental state, force of…
- Trial name
- NCT05449379
- Testing
- Respiratory training with the use of resistance set on respiratory muscle trainer, Respiratory training without resistance set on respiratory muscle trainer
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Bialystok
Other Complications of Esophagostomy
Outcome Study of Restrictive vs. Liberal Intraoperative Fluid Management Guided by PPV in Esophagectomy
The purpose of this study is to determine whether intraoperative restrictive fluid management guided by pulse pressure variation produces a better effect on the postoperative lung function, kidney function, inflammatory response…
- Trial name
- PPV (NCT01933451)
- Testing
- Intraoperative fluid therapy
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- National Taiwan University Hospital
Oxygen Toxicity
Pulmonary Function After Hyperbaric Oxygen Therapy
Patients receiving hyperbaric oxygen therapy (HBOT) for any indication at the Hyperbaric Medicine Unit (University Health Network, Toronto, ON, Canada) from 2016-2021 were recruited to this prospective cohort study.
- Trial name
- NCT05088772
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- University of Toronto
COVID-19
Association of Phenotypic Age and Antibody Titers Among SARS-Co-V2 Infected Patients and Vaccinated Groups
Defining the antibody response to SARS-CoV-2 will be essential for understanding disease progression, long-term immunity, and vaccine efficacy.
- Trial name
- NCT05827939
- Testing
- Covid19 Vaccination dose
- Where
- Taiwan
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Alcoholism, Respiration, Artificial
Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam
The aim of this study is to evaluate the effects of the sedatives propofol and midazolam on stress response and immune function in critically ill patients with alcohol use disorders who are undergoing mechanical ventilation.
- Trial name
- NCT00871039
- Testing
- Propofol, Midazolam
- Where
- 2 sites in United States
- Sponsor
- Virginia Commonwealth University
SBRT, Non-small Cell Lung Cancer
Lung Perfusion PET / CT Using Ga68-MAA for Preservation of Lung Function During Stereotactic Pulmonary Radiation Therapy
This is a prospective study evaluating the feasibility of treatment planning integrating lung perfusion PET/CT using Ga68-MAA to preserve functional lung areas during stereotactic body radiation therapy (SBRT).
- Conditions
- SBRT, Non-small Cell Lung Cancer, Lung Metastasis
- Trial name
- PEGASUS (NCT04942275)
- Testing
- Pre-therapeutic imaging test
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Immune Function, Immunity
Effects of TM02® Supplementation on Immune Function in Children
This randomized, double-blind, placebo-controlled clinical study evaluated the effects of 12 weeks of TM02® supplementation on immune-related outcomes in generally healthy children aged 2 to 12 years.
- Trial name
- NCT07853573
- Testing
- TM02®
- Where
- Malaysia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ligno Biotech Sdn. Bhd.
Chronic Venous Insufficiency
Respiratory and Physical Functions in Individuals With Chronic Venous Insufficiency
In the literature, it is still unclear whether individuals with chronic venous insufficiency are affected by edema, pain, respiratory muscle strength, respiratory functions, functional capacity, lower extremity strength and…
- Trial name
- NCT06196541
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Long COVID-19, Post-COVID-19 Syndrome
Effects of a Home-Based Exercise Intervention in Subjects with Long COVID
The current Coronavirus Disease 2019 (COVID-19) pandemic is the most severe health crisis of the 21st century. This is not only due to the deaths caused by the disease.
- Trial name
- NCT06073002
- Testing
- home-based concurrent exercise
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- University of Vienna
Cystic Fibrosis
Ghrelin in Cystic Fibrosis
Background to ghrelin Ghrelin is a naturally occurring hormone found in the blood which stimulates appetite. In healthy individuals, levels of ghrelin are high before a meal and falls afterwards.
- Trial name
- ghrelin (NCT00763477)
- Testing
- ghrelin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Water-Electrolyte Imbalance, Intensive Care Units
Fluid Overload and Pulmonary Function
Esophageal atresia is a rare but severe malformation, and it requires early surgery. Coloesophagoplasty is surgical repair of the esophageal with an isoperistaltic transverse colon graft.
- Conditions
- Water-Electrolyte Imbalance, Intensive Care Units, Pediatric, Critical Illness
- Trial name
- NCT05129930
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Pirogov Russian National Research Medical University
Lung Cancer
19F Thoracic Radiotherapy for Lung Cancer
The goal of this study is to determine the feasibility and efficiency of incorporating 19F MR functional lung imaging into the routine assessment of lung cancer patients prior to thoracic radiotherapy.
- Trial name
- NCT03315065
- Testing
- Perfluorinated Gas/Oxygen Mixture
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Hal C Charles
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