Clinical trials: Respiratory Function
Pneumonia Childhood, Rehabilitation
Clinical Efficacy of Respiratory Pediatric Physiotherapy on a Child With Hospital Treated Pneumonia
The accumulation of secretions in the bronchopulmonary air network promotes the detriment of respiratory functions generating hypoxia and causing a decrease in the cardiac output requiring the use of mechanical ventilation and…
- Conditions
- Pneumonia Childhood, Rehabilitation, Recovery of Function
- Trial name
- NCT06174454
- Testing
- Respiratory Pediatric Physiotherapy, Control Group
- Where
- Mexico
- Volunteers
- 88 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Liberation From Mechanical Ventilation in ICU Patients
Prediction of Successful Liberation From Invasive Mechanical Ventilation Via Lung and Diaphragmatic Ultrasound in Intensive Care Unit Patients, Prospective, Observational Study
Liberation from invasive mechanical ventilation (IMV) remains a challenge for intensive care physicians. Although standard indices such as blood gases and respiratory clinical data are used routinely but they still have some…
- Trial name
- NCT06461754
- Testing
- Sonographic evaluation of diaphragm and lung
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
COVID-19
Retrospective Study of COVID-19 on Reproductive Function
This multi-center, retrospective cohort study aimed to determine which factors are associated with ongoing pregnancy rates in infertile patients received ART treatments during the current outbreak of COVID-19 infection.Couples…
- Trial name
- NCT05685966
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Jinling Hospital, China
Sleep Apnea, Pediatric Sleep Apnea
Use of a 3D Printer to Make Custom Sleep Masks for Positive Airway Pressure Treatment
This is a small pilot study to look at the feasibility of creating a customized sleep mask for use with Continuous Positive Airway Pressure (CPAP) or other similar treatments for sleep apnea.
- Trial name
- NCT02896751
- Testing
- 3D printed NIV mask
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Mechanically Ventilated Patients
Effect of ERCC and/or PEEP-ZEEP Maneuver on Oxygenation, Ventilation, and Airway Secretions Removal in MV Patients
Mechanical ventilation (MV) is crucial in managing respiratory insufficiency. However, prolonged use can cause complications. Various strategies have been explored to optimize patient outcomes.
- Trial name
- NCT06182553
- Testing
- Expiratory Rib Cage Compression, PEEP-ZEEP Maneuver, ERCC + PEEP-ZEEP maneuver
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Obstructive Sleep Apnea (OSA)
Point of Care Ultrasound in Pregnant Women (PoCUS-OB)
Pregnant women with gestational age more than 20 weeks are at risk of developing Obstructive Sleep Apnea (OSA). OSA is a common underdiagnosed comorbid condition in pregnant women associated with adverse maternal and fetal…
- Trial name
- NCT06776237
- Testing
- PoCUS
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Stable COPD Patients
Effect of Vitamin D3 on Lung Function and Exercise Tolerance in COPD Patients
Background: Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world which is a preventable as well as treatable disease.
- Trial name
- NCT03781895
- Testing
- Cholecalciferol
- Where
- Bangladesh
- Volunteers
- 48 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Ventilation Therapy; Complications
Optimal PEEP in Pediatric Patients Under 17 Years of Age.
This study aimed to investigate the differences in positive end-expiratory pressure titration in the supine and prone positions by age in pediatric patients under 17 years of age who received general anesthesia and then evaluate…
- Trial name
- NCT05726877
- Testing
- ventilation strategy
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Seoul National University Hospital
Obstructive Sleep Apnea
Laboratory Assessment of Pilairo Q CPAP Mask Performance and Ease of Use.
Participants will undergo a normal sleep study. They will be randomised to use either a FPH Pilairo Q nasal pillow CPAP mask, or another mask.
- Trial name
- NCT02121912
- Testing
- FPH Pilairo Q CPAP mask, Any other market released nasal or nasal-pillow CPAP mask
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Fisher and Paykel Healthcare
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Evaluation of an Alternative Sizing Model in Comparison of a Conventional Sizing Model for Full Face Masks in the Treatment of OSA in Terms of Performance and Comfort
The investigation is a prospective non-blinded and semi-randomized clinical investigation. The investigation is designed to assess the alternative sizing model which the trial mask concept is based on and how it compares to a…
- Trial name
- NCT02851628
- Testing
- Alternative sizing model based trial mask, Prototype Full Face Mask
- Where
- 4 sites in New Zealand
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
Non-invasive Ventilation
Asynchronies in NIV With External Gas
NIV can be combined with other treatments that require to introduce gas into the circuit during the treatment. This external gas produces trigger asynchronies that worse depending on the model ventilator, trigger design and gas…
- Trial name
- NCT04884828
- Testing
- external gas during NIV
- Where
- Spain
- Volunteers
- 7 people
- Sponsor
- Corporacion Parc Tauli
Hypertrophic Cardiomyopathy
Ranolazine for the Treatment of Chest Pain in HCM Patients
The purpose of RHYME is to evaluate the safety and efficacy of ranolazine in Hypertrophic Cardiomypathy patients with chest pain or dyspnea despite treatment with standard medical therapy.
- Trial name
- RHYME (NCT01721967)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Healthy Vollunteer, Apnea
Temporal Dynamics of Peripheral SpO₂ During Reoxygenation
Pulse oximeters estimate arterial oxyhaemoglobin saturation (SaO₂) from photoplethysmographic signals recorded at peripheral sites (usually the fingertip), thus measuring the peripheral oxygen saturation (SpO₂).
- Trial name
- PulseOx (NCT07884500)
- Testing
- Voluntary Apnea
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
ARDS, Respiratory Effort
Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)
The objective of this research is to utilize respiratory effort parameters as a tool to assist in adjusting sedative drug levels for patients undergoing mechanical ventilation in the intensive care unit, in comparison to the…
- Conditions
- ARDS, Respiratory Effort, Mechanical Ventilation Complication, Sedation
- Trial name
- NCT06242236
- Testing
- The respiratory effort parameters guide sedative dosage.
- Where
- Thailand
- Volunteers
- 156 people
- Sponsor
- Ramathibodi Hospital
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis
MASLD in Type 2 Diabetes in Primary Care - a Follow-up Study
The goal of this observational study is to understand how metabolic dysfunction-associated steatotic liver disease (MASLD) changes over time in individuals with type 2 diabetes who previously participated in the EPSONIP study.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis, Advanced Fibrosis, Sarcopenia
- Trial name
- EPSOMIP2 (NCT07312136)
- Where
- Sweden
- Volunteers
- 317 people
- Sponsor
- Linkoeping University
Trauma, Cardiac Arrest
Airway Management Study in Physician Manned Helicopter Emergency Medical Services
An international airway management expert group has recently developed an Utstein-style template for uniform reporting of data from prehospital advanced airway management.
- Conditions
- Trauma, Cardiac Arrest, Emergencies
- Trial name
- AIRPORT (NCT01502111)
- Where
- Norway
- Volunteers
- 2,333 people
- Sponsor
- Norwegian Air Ambulance Foundation
Obstructive Sleep Apnea
Clinical Evaluation of a Wearable Technology for the Diagnosis of Sleep Apnoea
This trial will aim to test a new wearable device for the diagnosis of Sleep Apnoea.
- Trial name
- NCT04028011
- Testing
- Novel Wearable device
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Acurable Ltd.
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Breast Cancer, Postoperative Pain
The Effect of Rhomboid Intercostal Block and Serratus Anterior Plane Block on Postoperative Respiratory Functions
Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. Serratus anterior plane block is used to block lateral cutaneous branches of intercostal nerves between T2…
- Conditions
- Breast Cancer, Postoperative Pain, Respiratory Function Impaired
- Trial name
- RIBSAB (NCT05547932)
- Testing
- RIB+SAP blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Muğla Sıtkı Koçman University