Clinical trials: Respiratory Function
Muscle Weakness, Critical Illness
Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients
The investigators hypothesize that by applying a validated algorithm to accomplish early mobilization in surgical intensive care unit (ICU) patients, these patients will achieve a higher level of mobility which translates to…
- Conditions
- Muscle Weakness, Critical Illness, Respiratory Insufficiency
- Trial name
- mSOMS (NCT01363102)
- Testing
- SOMS
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Duchenne Muscular Dystrophy
Investigation of the Effects of Functional Inspiratory Muscle Training Applied With Tele-Rehabilitation on Respiratory and Functional Parameters and Quality of Life in Children With Duchenne Muscular Dystrophy: Randomized Controlled Study
Dushenne muscular dystrophy (DMD), which is characterized by the deficiency of dystrophin protein, prevents the muscle from maintaining its normal activity, causing progressive damage to the heart, respiratory muscles and…
- Trial name
- NCT07172737
- Testing
- Respiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Izmir Katip Celebi University
COPD
Validation of Urdu Version of Leicester Cough Questionnaire (LCQ)
Leicester Cough Questionnaire (LCQ) is a patient reported, 19-item tool, and it comprised physical, psychological, and social elements.
- Trial name
- NCT06674395
- Where
- Pakistan
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ventilation
Neurally Adjusted Ventilatory Assist (NAVA) in Pediatric Patients
The purpose of this study is to find out if NAVA-technology is better in detecting patients own inspiratory efforts during mechanical ventilation than currently used flow-triggering in PRVC (pressure regulated volume controlled)…
- Trial name
- NCT01056939
- Testing
- Neurally adjusted ventilatory assist, i-Servo, Maquet Nordic (Solna, Sweden), Control (PC- or PRVC- ventilation), i-Servo, Maquet Nordic (Solna, Sweden)
- Where
- Finland
- Volunteers
- 170 people
- Sponsor
- University of Oulu
Respiratory Insufficiency
VivaSight-SL™ Versus Bronchoscopy for Percutaneous Tracheotomy
Optical guidance for percutaneous tracheotomy in intensive care is usually performed by bronchoscopy. Recently, an endotracheal tube with a camera mounted at its tip (VivaSight-SL) has been introduced that allows for endotracheal…
- Trial name
- VivaPDT (NCT02861001)
- Testing
- conventional bronchoscopy, VivaSight-SL tube
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Acute Kidney Injury
Renal Replacement Therapy Plus Extracorporeal Carbon Dioxide Removal
This study aims to assess whether in patients with acute kidney injury (AKI) requiring mechanical ventilation, a strategy that combines renal replacement therapy (RRT) and extracorporeal carbon dioxide removal (ECCO2R) allows…
- Trial name
- NCT02595619
- Testing
- RRT plus ECCO2R
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Turin, Italy
COVID-19
The Evaluation of Hemostasis in Hospitalized COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been shown to predispose patients to thrombotic diseases (venous and arterial) with…
- Trial name
- TARGET-COVID (NCT04493307)
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
Acute Respiratory Distress Syndrome, ARDS
Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure
This is a quality improvement study with the purpose of observing and measuring the effects of implementation of a proven standardized lung protective ventilation protocol in the new electronic medical record system iCentra…
- Conditions
- Acute Respiratory Distress Syndrome, ARDS, Respiratory Distress Syndrome, Acute, Respiratory Insufficiency
- Trial name
- IMPROVENT (NCT03225807)
- Where
- United States
- Volunteers
- 8,692 people
- Sponsor
- Intermountain Health Care, Inc.
Airway Obstruction, Pain
Dental Isolation Systems Among Pediatric Patients With Different Airway Patency
This randomized clinical trial will aim to evaluate the effect of DryShield isolation (DSI) and Rubber Dam isolation (RDI) systems on arterial oxygen saturation (SpO2), heart rate (HR), blood pressure (BP), behavior, subjective…
- Conditions
- Airway Obstruction, Pain, Behavior
- Trial name
- NCT06128811
- Testing
- Rubber Dam Isolation, DryShieled isolation, fissure sealant
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Preterm
Effects of Non-Traumatic Nasopharyngeal Suction Technique in Infants
Background: Non-invasive ventilation (NIV) in preterm infants often leads to secretion-related airway obstructions, requiring suctioning.
- Trial name
- NCT07111611
- Testing
- Non-Traumatic Nasopharyngeal Suction Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Labor Pain
Effectiveness of Backside Massage and Lamaze Breathing on Labour Outcome Among Primigravida
The study aims to investigate the effects of a combination of Lamaze breathing exercises and backside massage on the labor experiences of primigravidae in Pakistan.
- Trial name
- NCT06304311
- Testing
- Routine Obstetrics care & Lamaze breathing techniques and backside massage, Routine obstetrics care
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Transcervical Resection of Endometrium, Transcervical Resection of Fibroids
Comparing Two Types of Sedation to Gynaecological Patients
The primary endpoint is to investigate the difference in pain between patients who receive deep sedation with spontaneous breathing versus patients who receive general anesthesia.
- Conditions
- Transcervical Resection of Endometrium, Transcervical Resection of Fibroids, Transcervical Resection of Polyp
- Trial name
- NCT01412632
- Testing
- Remifentanil, propofol and citanest
- Where
- Denmark
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Acute Respiratory Distress Syndrome
Long Term Outcome on Brain and Lung of Different Oxygen Strategies in ARDS Patients
Acute respiratory distress syndrome (ARDS) is a serious disease with high mortality. In patients who survive ARDS, respiratory, neurological and motor sequelae are frequent, negatively impacting on the patient's quality of life…
- Trial name
- LTO-BLOXY (NCT03621293)
- Testing
- Modulation of Inspired Fraction of Oxygen (FiO2)
- Where
- France
- Volunteers
- 259 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Kidney Diseases, Insomnia
4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis
For many hemodialysis patients, fatigue and sleep disturbances are common and debilitating side effects that severely impact daily life and quality of life.
- Conditions
- Chronic Kidney Diseases, Insomnia, 4-7-8 Breathing Technique
- Trial name
- NCT07700693
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
New Onset Atrial Fibrillation, Sepsis
Rapid Atrial Fibrillation Treatment Strategy
Prospective, randomized, open-label clinical trial studying the treatment of new onset atrial fibrillation in critically ill patients with septic shock.
- Conditions
- New Onset Atrial Fibrillation, Sepsis, Respiratory Failure
- Trial name
- RAFTS (NCT04092621)
- Testing
- Amiodarone in Parenteral Dosage Form, Amiodarone Pill, Direct Current Cardioversion (DCC)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Our Lady of the Lake Hospital
ARDS (Acute Respiratory Distress Syndrome)
Pressure Release Ventilation Compared to Lung Protective Ventilation in Moderate and Severe ARDS
This study compares two different ways of providing mechanical ventilation to patients with moderate to severe acute respiratory distress syndrome (ARDS), a serious condition in which the lungs become inflamed and make it…
- Trial name
- NCT07803614
- Testing
- Arm 1 Intervention Name: Low-Tidal-Volume Ventilation (LTV)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Koot Ahmad
COVID-19 Acute Respiratory Distress Syndrome, Respiration, Artificial
Flow-controlled Ventilation (FCV) in Moderate Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19
Flow controlled ventilation (FCV) is a fairly new mode of mechanical ventilation, consisting of a constant inspiratory and expiratory flow. Inspiration is thus comparable to volume controlled ventilation (VCV).
- Trial name
- VICAR (NCT04894214)
- Testing
- Arterial blood gas (ABG), Recording of hemodynamic monitoring, Recording of respiratory monitoring
- Where
- Belgium
- Volunteers
- 11 people
- Sponsor
- University Hospital, Antwerp
Stress, Psychological, Stress, Physiological
Effects of Relaxing Breathing With Biofeedback or Meditative Stimulation on Performances During OSCE of Medical Students
Objective Structured Clinical Examination (OSCE) is a newly implemented evaluation standard for medical student and is a determinant part of the national competition they have to undergo.
- Conditions
- Stress, Psychological, Stress, Physiological, Exam Stress, Performance Anxiety
- Trial name
- ECOSTRESS (NCT05136586)
- Testing
- Biofeedback, Meditation, Control and biofeedback post OSCE
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Sleep Apnea, Obstructive
Comparison of the Pentax AWS® With the Macintosh Laryngoscopic Intubation in Obstructive Sleep Apnea Syndrome Patients
The Pentax-AWS_ system (AWS; Pentax Corporation, Tokyo, Japan) is a new rigid indirect laryngoscope which has an integrated tube passage function.
- Trial name
- NCT01428570
- Testing
- Pentax-AWS (AWS; Pentax Corporation, Tokyo, Japan)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyunghee University Medical Center