Clinical trials: Respiratory Failure (Pediatric Patients)
Respiratory Failure
Sedation Management in Pediatric Patients Supported on Mechanical Ventilation
The purpose of this two-year project is to pilot test an intervention to change sedation management in pediatric patients supported on mechanical ventilation for acute respiratory failure in the pediatric intensive care unit…
- Trial name
- NCT00142766
- Testing
- Nurse Implemented Goal-Directed Comfort Algorithm
- Where
- 3 sites in United States
- Volunteers
- 245 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bronchiolitis, Respiratory Failure (Pediatric Patients)
Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit
Bronchiolitis is a leading cause of pediatric hospital admissions. Despite its limited clinical benefits, the use of HFNC in children with bronchiolitis is increasing.
- Conditions
- Bronchiolitis, Respiratory Failure (Pediatric Patients), High Flow Nasal Cannula
- Trial name
- NCT06621641
- Testing
- The new HFNC weaning protocol
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
This prospective observational study will evaluate the safety and performance of the MiniLung petite kit in neonatal and pediatric patients with acute respiratory and cardiac failure.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia, Acute Respiratory Failure, Acute Lung Injury
- Trial name
- PETIT (NCT06750536)
- Testing
- MiniLung petite kit combined with the Xenios console
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Xenios AG
Pediatric Acute Respiratory Distress Syndrome
Comparison of Oxygenation Index and Oxygen Stretch Index
Pediatric acute respiratory distress syndrome (pARDS) is a heterogeneous clinical syndrome that causes high rates of mortality and morbidity.
- Trial name
- NCT06586411
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Chronic Lung Disease, Quality of Life
Pulmonary Rehabilitation and Quality of Life in Children With Chronic Lung Diseases: A Multidisciplinary Approach
Chronic lung diseases (CLDs) such as asthma, cystic fibrosis, and bronchopulmonary dysplasia significantly impact pediatric patients' respiratory function and overall well-being.
- Conditions
- Chronic Lung Disease, Quality of Life, Respiratory Function Impaired
- Trial name
- NCT06870032
- Testing
- standard medical care, structured pulmonary rehabilitation
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Horus University
Acute Respiratory Failure, Pediatric Respiratory Distress Syndrome
Closed-loop Synchronization Versus Conventional Synchronization
A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient.
- Trial name
- CHESTSIPP (NCT05731024)
- Testing
- close-loop synchronization controller with SPONT mode, Conventional synchronization settings with SPONT mode
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Respiratory Failure (Pediatric Patients)
BPOI (Berlin Pediatric Oxygenation Index) - A New Predictor for Imminent Failure of HFNC in Children Avoiding Delayed NIV or Intubation
The investigators developed an index that integrates different flow-settings in High-flow nasal cannula (HFNC) therapy with non-invasively measured clinical parameters of oxygenation in pediatric patients.
- Trial name
- NCT04895332
- Sponsor
- Charite University, Berlin, Germany
Respiratory Failure
Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients
During mechanical ventilation (MV) hypoxemic or hyperoxemic events should be carefully monitored and a quick response should be provided by the caregiver at the bedside.
- Trial name
- CLOUDIMPP (NCT05714527)
- Testing
- Close-loop FiO2 controller, Conventional
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock
Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial
Background: China's healthcare system for children faces significant challenges, particularly due to the limited pediatric service capacity of primary healthcare institutions.
- Conditions
- Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock, Hand-foot-and-mouth Disease, Acute Appendicitis
- Trial name
- NCT06699433
- Testing
- Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos
- Where
- 3 sites in China
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Southern Medical University, China
Chronic Respiratory Failure, Tracheostomy Complication
Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
This study involves conducting a telephonic or in person survey regarding parental perception and attitudes about vaccinating the respective "technology dependent" child with the COVID 19 vaccination.
- Conditions
- Chronic Respiratory Failure, Tracheostomy Complication, Mechanical Ventilation Complication
- Trial name
- NCT05084976
- Testing
- COVID 19 vaccine counseling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
Acute Respiratory Failure, Acute Respiratory Infection
Airway Inflammatory Response During Illness in Children With Respiratory Failure
The purpose of this study has two major goals: 1) to measure the amount of two specific hormones interleukin (IL)-10 and interleukin (IL)-12p70 in mucous and blood; and 2) compare the hormone levels in two specific areas of the…
- Conditions
- Acute Respiratory Failure, Acute Respiratory Infection, Acute Respiratory Distress Syndrome
- Trial name
- NCT02047877
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Acute Respiratory Distress Syndrome, Pneumonia in Children
Using Artificial Intelligence To Improve Ventilator Settings For Intensive Care Patients
This observational study aims to determine whether an AI-assisted decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU, compared to standard…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients)
- Trial name
- NCT07592039
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Wu Rongzhou