Clinical trials: Resilience
Resilience, Psychological
Resilience Intervention for Older, HIV-Infected Women
The goal of this study is to refine and pilot the Relaxation Response Resiliency (3RP) intervention for women age 50 and over who are living with HIV, a group especially burdened by stressors related both to aging and living with…
- Trial name
- BRIgHT (NCT03071887)
- Testing
- Relaxation Response Resiliency Program (3RP)
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Massachusetts General Hospital
Type 1 Diabetes
Diabetes Strengths Study - Pilot of Provider-delivered Strengths-based Intervention
The purpose of this study is to determine whether a newly developed intervention is feasible and acceptable to adolescents with type 1 diabetes and their families and diabetes care providers, and to evaluate trends in whether the…
- Trial name
- DSS (NCT02510664)
- Testing
- Diabetes Strengths Study
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Baylor College of Medicine
Stress
Exploring the Effects of Muse and Spire on Stress Management
The goal of this study is to evaluate the effectiveness of Spire and Muse on stress management. The study will be implemented as a 2-arm randomized controlled pilot study to assess the effect of either device on stress management…
- Trial name
- Stressless (NCT02786771)
- Testing
- Spire, Muse headband
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Promoting Resilience in Women With Breast Cancer
The PRISM (Promoting Resilience in Stress Management) intervention is an evidence-based program that builds resilience. This program was developed in adolescent and young adult oncology and utilizes centrally administered…
- Trial name
- PRISM (NCT06133348)
- Testing
- Promoting Resilience in Stress Management Intervention
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Alabama at Birmingham
Healthy Volunteers
Effect of Ketamine on Laboratory-induced Stress in Healthy Subjects
The objective of this study is to examine the effect of a single IV dose of ketamine (0.5 mg/kg) on laboratory-induced stress in healthy participants.
- Trial name
- NCT04173962
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
PTSD
Sex/Gender Differences in Risk and Resilience to PTSD; Implication of Oxytocin
The purpose of the study is to use fMRI to investigate amygdala response to fearful faces in men and women with and without PTSD who have experienced childhood trauma.
- Trial name
- NCT01963078
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Megan Moran-Santa Maria
Suicide, Surveillance
Southwest Hub for American Indian Youth Suicide Prevention Research
1. To use a SMART design to evaluate which of four sequences of New Hope (NH), Elders Resilience (ER) and Case Management (CM) have the greater effects on immediate and longer-term suicidal ideation (primary outcome) and…
- Conditions
- Suicide, Surveillance, Mental Health, Substance Use
- Trial name
- NCT03543865
- Testing
- New Hope (NH), Elders Resilience (ER), Case Management (CM)
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Congenital Heart Disease
Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease
The purpose of this study is to evaluate the feasibility and preliminary efficacy of the Promoting Resilience in Stress Management (PRISM) intervention in patients with adult congenital heart disease.
- Trial name
- PRISMACHD (NCT04738474)
- Testing
- Promoting Resilience in Stress Management (PRISM), Usual Care
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
Shame
Piloting a Motivational Interviewing Shame-Resilience Training
The purpose of this study is to evaluate the shame resilience theory in a pilot context to assess its feasibility in a potential full scale clinical trial.
- Trial name
- MIST (NCT05106959)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
A. Longitudinal Cohort n=400, B. Lower Risk (n=45) and Higher Risk (n=105) Randomized 2:1 to PERCCS Intervention
Study to Understand Risk and Resilience Opportunity for Newborns After Delivery
Childhood Maltreatment (CM) has highly deleterious effects on human development and is a preventable known cause of enduring psychopathology in the United States.
- Trial name
- SURROuND (NCT04438161)
- Testing
- PERCCS: Personalized Education Regarding Clinical and Community Supports
- Where
- United States
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Community Mental Health Services, Adolescent Well Being
Prevention and Early Identification for High Risk Youth in School-based Clinics
The proposed research project provides a novel approach to screening, early assessment, and preventive interventions for high-risk youth in racial/ethnic/linguistically (REL)-diverse communities.
- Conditions
- Community Mental Health Services, Adolescent Well Being, Resilience, Psychological, Health Equity
- Trial name
- NCT04935710
- Testing
- COPE2Thrive, Usual care
- Where
- 5 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Cancer, Hypertension
Tailored Home-Based Exercise Program for Multiple Chronic Conditions
A home-based, tailored, technology-enhanced home-based exercise program (iHBE) using a combination of the integrated mobile technologies (wearable device and phone application) and tailored home-based exercise will be pilot…
- Conditions
- Cancer, Hypertension, Diabetes
- Trial name
- iHBE (NCT03874754)
- Testing
- Tailored Technology-Enhance Home-based exercise program (iHBE)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Oxytocin, Placebo
The Biology of Resilience
Positive social relationships have consistently been associated with better health, although the neurobiological underpinnings of these observed effects remain largely unknown.
- Trial name
- NCT01011465
- Testing
- intranasal oxytocin, Social support, No Social Support
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Stress, Professional, Stress, Psychological
Brief Mindfulness Meditation Course to Reduce Stress in Healthcare Professionals
Stress among healthcare professionals is well documented. Untreated stress can lead to anxiety, depression, substance use, and suicide.
- Trial name
- NCT03781336
- Testing
- Mindfulness-based self care
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Post Traumatic Stress Disorder, Problem Drinking
Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)
Sexual assault victimization is a common and particularly harmful form of trauma that is associated with increased risk for high-risk drinking and other conditions of public health concern, such as PTSD.
- Trial name
- NCT03703258
- Testing
- App-based intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Washington
Stress (Psychology)
Mobile Self-Management Program for Stress Reduction in Young Adults
The goal of this clinical trial is to learn if a mobile self-management program that combines Positive Psychology (PP) and Behavioral Activation (BA) helps reduce stress in young adults in South Korea.
- Trial name
- NCT07174544
- Testing
- Mobile Self-Management Program integrated with Positive Psychology and Behavioral Activation
- Where
- South Korea
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Covid19, Mental Health Issue
CRISOL Contigo: a Multi-level Intervention to Reduce the Disproportionate Toll of COVID-19 Among Latino Communities in Philadelphia.
Latinos have been one of the racial/ethnic groups most impacted by the COVID-19 pandemic, and evidence of effective strategies to curb the pandemic, reduce disparities, and mitigate its impact is lacking and very urgent.
- Conditions
- Covid19, Mental Health Issue, Violence
- Trial name
- CRISOL Contigo (NCT04646616)
- Testing
- Community popular opinion leader (POL) based intervention
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Drexel University
Resilience, Stress
First Responder Resiliency Program During COVID-19
Evaluating a wellness program developed to provide effective sustainable solutions for medical professionals providing care to COVID-19 pandemic patients.
- Conditions
- Resilience, Stress, Sleep
- Trial name
- NCT04536376
- Testing
- Resilience Program
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hereditary Cancer, Mental Health Issue
Previvors Recharge: A Resilience Program for Cancer Previvors
It is estimated that 1 in 279 people may be carriers of a Hereditary Cancer Syndromes (HCS), a cancer risk that is associated with germline mutations (inherited genetic mutations passed directly from a parent to a child that…
- Trial name
- PreCharge (NCT06378749)
- Testing
- PreCharge
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Human Immunodeficiency Virus, Depression
Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa
The purpose of this study is to test the efficacy of Our Family Our Future, an integrated intervention for preventing HIV and depression onset among adolescents.
- Conditions
- Human Immunodeficiency Virus, Depression, Sexually Transmitted Diseases
- Trial name
- NCT03231358
- Testing
- Our Family Our Future
- Where
- South Africa
- Volunteers
- 1,758 people, healthy volunteers welcome
- Sponsor
- Brown University