Clinical trials: Renal Ischemia
Cardiogenic Shock, Acute Decompensated Heart Failure
SURPASS Impella 5.5 Study
A multi-center, prospective \& retrospective, observational single-arm study of the clinical outcomes up to one year collected from electronic health records of patients which have undergone standard of care implantation of…
- Trial name
- NCT05100836
- Testing
- Impella 5.5
- Where
- 15 sites in United States
- Volunteers
- 1,017 people
- Sponsor
- Abiomed Inc.
Acute Kidney Injury
Remote Ischemic Preconditioning as a New Method of Nephroprotection
Remote ischemic preconditioning (RIPC), elicited by brief episodes of ischemia and reperfusion in distant tissue, offers a protection against acute kidney injury (AKI) in patients after cardiac surgery.
- Trial name
- NCT03205410
- Testing
- remote ischemic preconditioning, no - remote ischemic preconditioning
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lodz
Stroke, Transient Ischemic Attack
Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study
Prospective observational multicenter study to evaluate copeptin as a prognostic marker in patients with an acute cerebrovascular event.
- Trial name
- CoRisk (NCT00878813)
- Testing
- Sampling of 15ml blood, Blood-Sampling
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 1,102 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Renal Insufficiency, Acute Coronary Syndrome
Acute Renal Insufficiency (ARI) Rate and Predictive Score of ARI in Hospitalized Patients for Acute Coronary Syndrome With ST-segment Elevation Needing Urgent Coronarography
The primary objective of the study aims to evaluate frequence of acute renal insufficiency in patients with ST-segment elevation who need urgent coronary angiography in Ambroise Paré hospital.
- Trial name
- COROAKI (NCT04481126)
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myocardial Infarction, Diabetes Mellitus
Low Dose Ticagrelor Versus Low Dose Prasugrel in Patients With Prior Myocardial Infarction
Taken together the results from DAPT and PEGASUS-TIMI54, it appears that physicians may consider extending beyond 1 year or reinitiating treatment with a thienopyridine or ticagrelor 60mg bid in patients with a prior MI and…
- Conditions
- Myocardial Infarction, Diabetes Mellitus, Coronary Artery Disease, Renal Disease
- Trial name
- ALTIC-2 (NCT03387826)
- Testing
- Ticagrelor 60 mg, Prasugrel 5mg
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Attikon Hospital
Kidney Failure, Chronic, Kidney Transplantation
Drone Transport of Deceased-Donor Kidney Grafts Between Two French Hospitals Before Transplantation: a Pilot Safety Study
Cold ischemia time, the period during which a donated kidney is kept cold outside the body between its removal from the donor and its transplantation into the recipient, is one of the main modifiable factors influencing how…
- Conditions
- Kidney Failure, Chronic, Kidney Transplantation, Delayed Graft Function, Cold Ischemia
- Trial name
- RAfALREIN (NCT07851571)
- Testing
- Kidney graft transport by autonomous unmanned aircraft (drone) between the procurement and transplantation centres
- Volunteers
- 5 people
- Sponsor
- Nantes University Hospital
Hypertension, Ischemic Heart Disease
A Morbidity-Mortality and Remodeling Study With Valsartan
The JIKEI HEART Study has been designed to investigate whether concomitant treatment with valsartan, an angiotensin II receptor blocker (ARB), in addition to conventional treatment, will improve the prognosis of 3000 Japanese…
- Conditions
- Hypertension, Ischemic Heart Disease, Congestive Heart Failure
- Trial name
- NCT00133328
- Testing
- valsartan
- Where
- Japan
- Volunteers
- 3,000 people
- Sponsor
- Jikei University School of Medicine
Renal Function, Renal Injury
Analysis of Remote-ischemic Preconditioning Effects on Kidney Function
Patients with impaired renal function are at elevated risk for development of acute kidney injury (AKI). AKI is associated with increased risk for cardiovascular morbidity and mortality.
- Trial name
- RenPRO-TAVI (NCT01925235)
- Testing
- remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Chronic Kidney Diseases, Coronary Heart Disease
Cardiovascular-Renal Adverse Prognosis Assessment System for Coronary Heart Disease With Chronic Kidney Disease Based on Metabolomics
Coronary heart disease (CHD) combined with chronic kidney disease (CKD) affects a substantial portion of the population and carries a significant disease burden, often leading to poor outcomes.
- Conditions
- Chronic Kidney Diseases, Coronary Heart Disease, Lipid Metabolism Disorders
- Trial name
- CRUISE-MET (NCT06383208)
- Testing
- lipid metabolomics
- Where
- China
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Acute Kidney Injury, Dialysis
Renal Effects of RIPC in Patients After Total Arch Replacement
The purpose of this study is to test the hypothesis that remote ischemic preconditioning prevents acute kidney injury and improves clinical outcomes in patients undergoing total arch replacement.
- Trial name
- RenRIPC-TAR (NCT03141385)
- Testing
- remote ischemic preconditioning, Control
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Ischemia-reperfusion Injury, Kidney Transplant; Complications
A Trial to Assess Efficacy and Safety of ex Vivo Allograft Admin of iCM012 Solution 2 mg/ml to Improve Its Function in Recipients of DCD Kidneys
Randomized (1:1), placebo controlled, double blind efficacy trial. 200 patients will be followed up for 12 months post transplantation.
- Trial name
- NCT06582485
- Testing
- iCM012 solution 2 mg/mL
- Volunteers
- 200 people
- Sponsor
- iCoat Medical AB
Acute Kidney Injury
Ciclosporin to Protect Renal Function In Cardiac Surgery
The purpose of this study is to evaluate the potential of ciclosporin in reducing risk and degree of acute kidney injury after cardiac surgery.
- Trial name
- CiPRICS (NCT02397213)
- Testing
- Ciclosporin
- Where
- Sweden
- Volunteers
- 155 people
- Sponsor
- Region Skane