Clinical trials: Renal Hemodynamics
CHF, Renal Disease
Validation of a Sensor for Non-Invasive Measurements
Subjects will be measured with both a sensor and a reference device
- Conditions
- CHF, Renal Disease, Hypertension
- Trial name
- NCT03463148
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Baxter Healthcare Corporation
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Obesity, Bariatric Surgery
Impact of Weight Loss After a Bypass Surgery on Renal Hemodynamic Under Stress Conditions
The sympathetic nervous (SNS) and the renin angiotensin aldosterone system (RAS) have a direct impact on renal hemodynamic, hormonal secretion and vasoactive peptide.
- Conditions
- Obesity, Bariatric Surgery, Blood Pressure
- Trial name
- OBBYSS (NCT02218112)
- Testing
- bariatric surgery (gastric bypass)
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Chronic Kidney Disease
Evaluation of Fructose Ingestion and the Renin Angiotensin System in Humans
Fructose is an ingredient that is added to many of our foods. It is a cheaper, sweeter additive that can be found in everything from soda pop to yogurt to granola bars.
- Trial name
- NCT01407627
- Testing
- Fructose
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Type 2 Diabetes Mellitus
TRENDY Follow-up: Study on Endothelial Function in Subjects With Type 2 Diabetes Mellitus
Basal nitric oxide (NO) activity plays a pivotal role in the regulation of glomerular hemodynamics, and in animal experiments its alteration has been associated with morphological changes characteristic of diabetic nephropathy.
- Trial name
- NCT00905528
- Testing
- Telmisartan 80 mg/d, Ramipril 10 mg/d
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Kidney Diseases, Renal Failure
IntraRenal HEmoDynamics to IntegraTE CA-AKI Risk and Monitor NephroprotectiIoN by ImpElla Support.
the hypothesis is that elevation of the intrarenal resistive index (RI) characterizes patients at elevated risk for subsequent CA-AKI and integrates items of the Mehran AKI risk score into a single, readily obtainable parameter.
- Conditions
- Chronic Kidney Diseases, Renal Failure, Coronary Artery Disease
- Trial name
- NCT06599424
- Testing
- Observational
- Where
- 2 sites in Germany
- Volunteers
- 550 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
End Stage Renal Disease on Dialysis, Hemodialysis Complication
Virtual Reality Intradialysis: Last vs. First Part of the Session
The main objective of this investigation is to assess if an intradialysis virtual reality exercise program during the last two hours of the hemodialysis session results in greater hemodynamic stability than exercise performed…
- Trial name
- VRI (NCT04046042)
- Testing
- Conventional exercise, Exercise during the last two hours of the hemodialysis session
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Acute Kidney Injury, Cardiac Surgery
Acute Kidney Injury After Cardiac Surgery
Acute kidney injury (AKI) is common after cardiac surgery. The diagnosis is based on the criteria defined by the Kidney Disease Improving Global Outcomes (KDIGO) classification: oliguria and elevation of serum creatinine.
- Trial name
- NEPHROCAR (NCT03396770)
- Testing
- Standard clinical routine, Nephrocheck test
- Where
- France
- Volunteers
- 848 people
- Sponsor
- Rennes University Hospital
Remimazolam, Propofol
Remimazolam on the Incidence of Postoperative Acute Kidney Injury
We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the…
- Conditions
- Remimazolam, Propofol, Acute Kidney Injury, Hemodynamic Stability
- Trial name
- NCT07674719
- Testing
- Remimazolam (Byfavo), propofol
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Heart Failure
Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients
The purpose of the present study is to evaluate the effects of a blockade of the vasopressin system and central hemodynamic system in heart failure (HF) patients during physical exercise.
- Trial name
- NCT01752543
- Testing
- Conivaptan
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Finn Gustafsson
Diabetes Mellitus, Diabetic Kidney Disease
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study
SGLT2 inhibitors such as ertugliflozin improve blood pressure and kidney outcomes in people living with diabetes through incompletely understood mechanisms, however, not all patients treated with SGLT2 inhibition have improved…
- Conditions
- Diabetes Mellitus, Diabetic Kidney Disease, Hypertension
- Trial name
- DESIGN (NCT05727579)
- Testing
- Salt-Diet and/or Ertugliflozin, Ertugliflozin 15 mg
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Amsterdam UMC, location VUmc
Renal Dialysis, Hemodynamics
The LIPMAT Study: Liposomal Prednisolone to Improve Hemodialysis Fistula Maturation
This study will investigate if liposomal prednisolone is effective in promoting arteriovenous fistula (AVF) maturation when administered to human subjects after surgical creation of a radio-cephalic AVF.
- Conditions
- Renal Dialysis, Hemodynamics, Vascular Remodeling, Neointima
- Trial name
- LIPMAT (NCT02495662)
- Testing
- PEG-liposomal prednisolone sodium phosphate
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
Type 2 Diabetes
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
SGLT2 inhibitors have demonstrated to mitigate cardiorenal risk in people with type 2 diabetes and are likely to play an increasingly large role in the treatment of patients with diabetes, chronic kidney disease and hypertension.
- Trial name
- DESIGN (NCT06983054)
- Testing
- ertugliflozine, low salt diet, high salt diet
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 34 people
- Sponsor
- Amsterdam UMC, location VUmc
Acute Kidney Injury
Circulatory Management and Acute Kidney Injury in Patients Undergoing Partial Nephrectomy
The purpose of this study is to investigate whether circulatory management based on LiDCOrapid hemodynamic monitoring can reduce the incidence of acute kidney injury in patients undergoing partial nephrectomy when compared with…
- Trial name
- NCT02803372
- Testing
- Goal-directed circulatory management, Routine circulatory management
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University First Hospital
Hemodialysis, Ischemia Preconditioning
Assessment of the Impact of Repeated Ischemic Preconditioning Episodes on Hemodynamic and Metabolic Parameters in Patients at Various Stages of Chronic Kidney Disease
The aim of our study is to evaluate the impact of repeated episodes of ischemic quenching on changes in blood pressure, heart rate and laboratory parameters of inflammation in patients with kidney diseases.
- Conditions
- Hemodialysis, Ischemia Preconditioning, Chronic Kidney Disease, Blood Pressure Disorders
- Trial name
- NCT07746102
- Testing
- Preconditioning with control ischemic episodes
- Where
- 2 sites in Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Hemodynamic Monitoring
Comparison of Transthoracic Electrical Bioimpedance and Pulse Contour Analysis in Renal Transplantation Patients
Hemodynamics monitoring using non-invasive transthoracic electrical bioimpedance ICON are compatible with standard invasive monitoring using pulse contour analysis EV1000
- Trial name
- NCT03893513
- Testing
- Transthoracic Electrical Bioimpedance, Pulse Contour Analysis
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dita Aditianingsih
Hypertension
Effects of Electrical Baroreflex Stimulation on Sympathetic Activity, Renal Hemodynamics, and Insulin Sensitivity
Electrical stimulation of carotid baroreceptors (baropacing) acutely decreases arterial pressure in patients with refractory hypertension.
- Trial name
- CVRX-ReSy (NCT01355510)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Hannover Medical School
Hemodynamic Monitoring
Starling/CRRT Observational Study
Hemodynamic optimization of critically ill patients is a goal for clinicians in order to afford the patient the best possible outcomes.
- Trial name
- NCT05729048
- Testing
- Starling
- Where
- United States
- Sponsor
- Baxter Healthcare Corporation
Cardiac Diseases, Cardio-pulmonary Bypass
A Monitoring System Based on the Multifactorial Dynamic Perfusion Index to Predict and Prevent the Onset of Postoperative Acute Kidney Injury After Cardiac Surgery, Based on a Dynamic Collection of Hemodynamic and Clinical Parameters During Cardiopulmonary Bypass
This project is based on a predictive alghorithm (Multifactorial Dynamic Perfusion Index-MDPI) already published and covered by a patent.
- Conditions
- Cardiac Diseases, Cardio-pulmonary Bypass, Acute Kidney Injury, Adult Cardiac Surgery
- Trial name
- PEQUOD 2 (NCT06786416)
- Testing
- PEQUOD
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Policlinico S. Donato
End Stage Kidney Disease
Hemodynamics in Chronic Hemodialysis Patients Undergoing Isolated Ultrafiltration Compared to Conventional Hemodialysis
Patients treated with hemodialysis (HD) bear increased risk of cardiovascular events, which results in high morbidity and mortality among this cohort of patients.
- Trial name
- ISO-UF (NCT05642156)
- Testing
- isolated Ultrafiltration (iso-UF)
- Where
- Austria
- Volunteers
- 32 people
- Sponsor
- Medical University of Graz