Clinical trials: Renal Artery Stenosis Atherosclerotic, active
Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease
Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease
This is a prospective, randomized, open-label, parallel-controlled clinical trial to evaluate the efficacy and safety of targeted IL-17A inhibition with secukinumab on cardiovascular and renal endpoints in 100 patients with…
- Conditions
- Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease, Coronary Artery Disease
- Trial name
- NCT07704190
- Testing
- Secukinumab (75 mg), Standard Medical Therapy
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
A Placebo-controlled Trial of Fractional Flow Reserve-guided Percutaneous Renal Artery Stenting Among Atherosclerosis Renal-vascular Hypertension Patients
Objective: To determine whether percutaneous renal artery stenting guided by fractional flow reserve (FFR), in addition to standard medical therapy, provides superior therapeutic efficacy compared to medical therapy alone in…
- Trial name
- FAIR (NCT07111442)
- Testing
- renal artery fractional flow reserve measurement, dopamine, renal artery stent
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Hypertension, Renovascular
Drug-eluting Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis--a Multicenter Study
The study will test the efficacy of drug eluting balloon(DEB) for non-atherosclerotic renal artery stenosis. The DEB (paclitaxel eluting balloon) will be used in the intervention group, while the plain old balloon(POB) will be…
- Trial name
- NCT05858190
- Testing
- Parallel Assignment
- Volunteers
- 90 people
- Sponsor
- Peking Union Medical College Hospital
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis
Although randomized trials have demonstrated there is no benefit of renal-artery stenting in addition to medical therapy for patients with atherosclerosis renal artery stenosis, many patients indeed gained benefit in daily…
- Trial name
- FAIR (NCT06447740)
- Testing
- Dopamine, Fractional Flow Reserve, Renal, Renal artery stenting
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Atherosclerotic Renal Artery Stenosis, Hypertension
Covered vs Bare Metal Stents for Atherosclerotic Renal Artery Stenosis
Atherosclerotic renal artery stenosis is the most common cause of secondary hypertension , increasing the risk of cardiovascular and kidney-related complications.
- Conditions
- Atherosclerotic Renal Artery Stenosis, Hypertension, Renal Artery Stenosis
- Trial name
- COMBAT (NCT07566065)
- Testing
- Covered Stent, Bare Metal Stent
- Where
- 15 sites in China
- Volunteers
- 150 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Atherosclerotic Renal Artery Stenosis, Fractional Flow Reserve
FFR-Guided Revascularization in Atherosclerotic Renal Artery Stenosis
For patients with atherosclerotic renal artery stenosis, the results of randomized controlled trials published in recent years have failed to demonstrate that renal artery stenting is superior to optimal medical therapy.
- Conditions
- Atherosclerotic Renal Artery Stenosis, Fractional Flow Reserve, Optimal Medical Therapy, Stent Implantation
- Trial name
- FARS (NCT07511309)
- Testing
- Randomized to stenting, stent implantation, Randomized to optimal medical therapy (OMT)
- Where
- 20 sites in China
- Volunteers
- 300 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Visceral Artery Aneurysm, Mesenteric Artery Ischemia
European Multicentre Study of Long-term Results Following Visceral Arteries Revascularization: the E-VisAR Study
Visceral arteries pathologies are a broad-spectrum of conditions with an extremely low incidence, estimated at 9.2% and 6.2% per 100,000 inhabitants for chronic and acute mesenteric ischemia, respectively, and 0.01-0.2% for…
- Conditions
- Visceral Artery Aneurysm, Mesenteric Artery Ischemia, Renal Artery Aneurysm, Renal Artery Stenosis
- Trial name
- E-VisAR (NCT06913530)
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Renovascular Hypertension, Renovascular Hypertension With Renal Failure
Effects of Percutaneous Transluminal Renal Angioplasty of Atherosclerotic Renal Artery Stenosis in High-Risk Patients.
The goal of this clinical trial is to investigate whether percutaneous transluminal renal angioplasty (PTRA) with stent placement of atherosclerotic renal artery stenosis is beneficial in high-risk patients selected according to…
- Conditions
- Renovascular Hypertension, Renovascular Hypertension With Renal Failure, Heart Failure, Renal Artery Stenosis Atherosclerotic
- Trial name
- DAN-PTRAII (NCT05834803)
- Testing
- Optimal medical therapy (OMT), Catheter-based angiography, Measurement of translesional pressure gradients
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus