Clinical trials: Renal Artery Stenosis
Renal Failure, Renal Artery Stenosis
Renal Blood Flow Measurement With Positron Emission Tomography (PET)
Two investigational chemical tracers, 62Cu-ethylglyoxal bis(thiosemicarbazone) (62Cu-ETS) and 15O-water, will be used in this study to look at how blood moves through the kidneys.
- Trial name
- NCT00714142
- Testing
- 62Cu-ethylglyoxal bis(thiosemicarbazone), 15O-water, Positron Emission Tomography
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jeffrey L. Lacy
Chronic Kidney Diseases
Assessment of Renal Vasculature and Function with Ferumoxytol-enhanced Magnetic Resonance Imaging
Conventional contrast-enhanced magnetic resonance imaging is typically performed with extracellular gadolinium chelates, which is often limited in patients with CKD owing to the risk of nephrogenic systemic fibrosis.
- Trial name
- NCT05045872
- Testing
- domestic polysaccharide superparamagnetic iron oxide nanoparticle
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Renal Artery Stenosis
Identification and Treatment of Renal Stenosis in Transplanted Kidneys
Renal artery stenosis is a complication that may follow kidney transplantation1-5. Renal artery stenosis greater than 50% of the lumen of the artery, associated with clinical symptoms or laboratory worsening of renal function…
- Trial name
- TRAS (NCT06822205)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Renal Artery Stenosis
Comparison of Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting
The clinical investigation is a prospective, international, multi-centre, randomized (1:1) trial with follow ups at 2, 6, 12 months and 3 years.
- Trial name
- RADAR (NCT00640406)
- Testing
- Dynamic Renal Stent plus Best Medical Treatment, Best Medical Treatment
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Biotronik AG
Renal Artery Stenosis, Renal Blood Perfusion
A Study of Using Parenchymal Blood Volume(PBV) for Endovascular Treatment of Renal Arterial Stenosis
This study will use PBV technique to quantitatively assess the improvement of renal perfusion before and after endovascular treatment (EVT) of renal artery stenosis.
- Trial name
- NCT03252639
- Testing
- EVT for RAS & PBV acquisition protocol for target kidneys
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Disease Management, Diabetes Complications
Determining Rates of Cardiovascular Complications Among Patients of a Managed Diabetes Care Program
The primary objective of this study is to identify whether cardiovascular complication rates are lower in patients who participate in managed diabetes care, in comparison to provincial and national rates.
- Conditions
- Disease Management, Diabetes Complications, Diabetic Vascular Complications, Diabetic Neuropathy
- Trial name
- DECIDE (NCT00498147)
- Testing
- ADEC Program
- Where
- Canada
- Volunteers
- 1,213 people
- Sponsor
- Group Health Centre
Aorto-Iliac Arterial Stenosis, Peripheral Arterial Disease
Aortoiliac Stenosis in Kidney Transplantation
The impact of aortoiliac stenosis on kidney transplant patients remains unclear. This study aims to investigate the safety and efficacy of kidney transplantation in patients with aortoiliac stenosis.
- Conditions
- Aorto-Iliac Arterial Stenosis, Peripheral Arterial Disease, Kidney Transplant Failure
- Trial name
- TASC (NCT06020534)
- Where
- Netherlands
- Volunteers
- 655 people
- Sponsor
- Erasmus Medical Center
Dehydration, Acute Myocardial Infarction
Hydration Status Assessment Through Body Composition Monitoring in Patients With Acute Myocardial Infarction
Aims: evaluate the hydric status through bioimpedance spectroscopy in consecutive acute myocardial infarction patients referred for primary PCI; assessment of renal artery stenosis incidence through renal angiography in…
- Conditions
- Dehydration, Acute Myocardial Infarction, Renal Artery Stenosis
- Trial name
- HYD-AMI (NCT02655341)
- Testing
- Body Composition Monitoring, Coronarography, Primary Percutaneous Coronary Intervention
- Where
- Romania
- Volunteers
- 400 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Renal Artery Obstruction, Hypertension, Renovascular
Endovascular Therapy for Renal Artery Stenosis in China
A multicenter prospective registry planned to recruit more than 5 000 patients with renal artery stenosis was carried out in China.
- Trial name
- ETRAS-China (NCT03080519)
- Testing
- Endovascular Therapy
- Where
- 16 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Hypertension, Atherosclerosis
Renal Artery Calcium and Hypertension
CT of the abdomen is a very common examination performed for various indications.One of the common findings is vascular calcifications including calcifications of the renal arteries.Calcifications in the carotid arteries and…
- Trial name
- NCT00388869
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
Fractional Flow Reserve to Determine Atherosclerosis Renovascular Hypertension Stenting
Although randomized trials have demonstrated there is no benefit of renal-artery stenting in addition to medical therapy for patients with atherosclerosis renal artery stenosis, many patients indeed gained benefit in daily…
- Trial name
- FAIR-Pilot (NCT05732077)
- Testing
- Dopamine, Fractional Flow Reserve, Renal, Renal artery stenting
- Where
- 13 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Transplant Renal Artery Stenosis
Retrospective Study of Patients Undergoing Percutaneous Intervention of the Transplant Renal Artery Stenosis
Renal transplantation is the standard treatment for patients with end-stage chronic kidney disease because it is effective in reducing the morbidity and mortality.
- Trial name
- TRAS (NCT04225338)
- Where
- 2 sites in Brazil
- Volunteers
- 313 people
- Sponsor
- Adriano Henrique Pereira Barbosa
Hypertension, Renovascular
Drug-eluting Balloon for Treatment of Non-atherosclerotic Renal Artery Stenosis
Efficacy of drug eluting balloon(DEB) for non-atherosclerotic renal artery stenosis will be tested in this study. The intervention group will be treated with paclitaxel eluting balloon.
- Trial name
- NCT04366596
- Testing
- Angioplasty with paclitaxel eluting balloon, Angioplasty with plain old balloon
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking Union Medical College Hospital
Hypertension, Renovascular
Renal Atherosclerotic Revascularization Evaluation: RAVE Study
The RAVE study will compare renal revascularization to medical management for people with atherosclerotic renal vascular disease (ARVD) and the indication for revascularization.
- Trial name
- NCT00127738
- Testing
- Angiographic renal revascularization
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease
Effect of Secukinumab on Cardiorenal Outcomes in Patients With Cardiorenal Metabolic Syndrome and Atherosclerotic Cardiovascular Disease
This is a prospective, randomized, open-label, parallel-controlled clinical trial to evaluate the efficacy and safety of targeted IL-17A inhibition with secukinumab on cardiovascular and renal endpoints in 100 patients with…
- Conditions
- Cardiorenal Metabolic Syndrome, Atherosclerotic Cardiovascular Disease, Chronic Kidney Disease, Coronary Artery Disease
- Trial name
- NCT07704190
- Testing
- Secukinumab (75 mg), Standard Medical Therapy
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Renal Artery Obstruction, Kidney Failure
Stenting in Renal Dysfunction Caused by Atherosclerotic Renal Artery Stenosis
Background: Atherosclerotic renal artery stenosis (ARAS) is associated with progressive loss of renal function and is one of the most important causes of renal failure in the elderly.
- Trial name
- NCT00150943
- Testing
- Renal artery stent
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- UMC Utrecht
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
A Placebo-controlled Trial of Fractional Flow Reserve-guided Percutaneous Renal Artery Stenting Among Atherosclerosis Renal-vascular Hypertension Patients
Objective: To determine whether percutaneous renal artery stenting guided by fractional flow reserve (FFR), in addition to standard medical therapy, provides superior therapeutic efficacy compared to medical therapy alone in…
- Trial name
- FAIR (NCT07111442)
- Testing
- renal artery fractional flow reserve measurement, dopamine, renal artery stent
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Hypertension, Hypertension Resistant to Conventional Therapy
Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis (ANDORRA)
The ANDORRA study is a, multicenter, prospective, open, randomized, controlled blinded endpoint trial (PROBE) comparing two treatment strategies (renal artery stenting + standardized and optimized medical treatment [SOMT] versus…
- Conditions
- Hypertension, Hypertension Resistant to Conventional Therapy, Angiographically Proven Grade III Unilateral or Bilateral Atherosclerotic Renal Artery Stenosis (ARAS) Greater Than or Equal to 60 Percent
- Trial name
- ANDORRA (NCT02539810)
- Testing
- Renal artery Angioplasty plus stenting., Anti hypertensive, statin and antiplatelet medication.
- Where
- 15 sites in France
- Volunteers
- 4 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atherosclerosis, Chronic Kidney Disease
Revascularization of Renal Artery Stenosis Versus Medical Therapy for the Treatment of Ischemic Nephropathy
The aim of the study is to value, in patients with chronic kidney disease and hypertension, whether medical therapy plus interventional renal artery revascularization is superior to medical therapy alone for the treatment of…
- Conditions
- Atherosclerosis, Chronic Kidney Disease, Hypertension, Renovascular, Ischemic Nephropathy
- Trial name
- NITER (NCT01023373)
- Testing
- Medical treatment, PTRS, renal artery stent
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Renal Artery Obstruction, Kidney Disease
MRI to Detect Embolism Following Angiography and Angioplasty-Stenting of the Renal Artery
This study will use magnetic resonance imaging (MRI) to picture the kidney and renal arteries (arteries that supply blood to the kidney) in patients scheduled for kidney artery angiogram and angioplasty/stenting procedures.
- Trial name
- NCT00027469
- Testing
- MRI
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)