Clinical trials: Relationship Distress, active
SMARD1, CMT2S
Gene Therapy for IGHMBP2-Related Diseases
Open-label, single intrathecal injection study of a AAV9 vector carrying the IGHMBP2 gene for IGHMBP2-related diseases.
- Trial name
- NCT05152823
- Testing
- Gene Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Megan Waldrop
Substance Abuse, Substance Addiction
The Trans-Led Care Study
This study is testing a new mutual-help group called "the TLC program" for transgender adults who use substances or are recently in recovery.
- Conditions
- Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol)
- Trial name
- TLC (NCT06880705)
- Testing
- The TLC Program
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Illinois Institute of Technology
Cancer, Financial Hardship
Feasibility of a Real-world, Financial Psycho-oncology Intervention to Address Cancer-related Financial Distress
The goal of this pilot, feasibility study is to evaluate the feasibility and preliminary impact of a finance-specific psycho-oncology intervention, as well as to explore perceptions of and experiences with this financial…
- Conditions
- Cancer, Financial Hardship, Psychological Distress
- Trial name
- NCT07724041
- Testing
- Financial psycho-oncology intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Child Development, Parenting
Impact of the Korea Early Childhood Home-visiting Intervention
Maternal and early childhood home visits have been proposed as an effective strategy to improve the health and development of disadvantaged children.
- Conditions
- Child Development, Parenting, Infant Development, Pregnancy Related
- Trial name
- KECHI (NCT04749888)
- Testing
- Targeted nurse-led home visiting
- Where
- 2 sites in South Korea
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Type 2 Diabetes
Digital Health Literacy and Diabetes Management in Type 2 Diabetes
This study aims to examine the relationships between digital health literacy, diabetes distress, diabetes self-management, and glycated hemoglobin (HbA1c) levels in individuals with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT07888972
- Where
- Turkey (Türkiye)
- Volunteers
- 348 people
- Sponsor
- Abant Izzet Baysal University
Lung Neoplasms, Psychological Distress
Association of Psychological Distress in Patients With Lung Cancer
Psychological distress is a multi-factorial experience of a psychological, social, spiritual, and/or physical nature that may interfere with one's ability to cope effectively with cancer, physical symptoms and treatment.
- Conditions
- Lung Neoplasms, Psychological Distress, Prognosis Factors, Lifestyle, Healthy
- Trial name
- Life-Score (NCT06218901)
- Testing
- immunotherapy, Targeted Therapy Agent
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Chest Hospital
Head and Neck Cancer, Body Image Disturbance
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
In this multi-center randomized clinical trial, head and neck cancer (HNC) survivors with clinically significant body image distress (BID) (N=180) will be randomized to BRIGHT (a brief video tele-cognitive behavioral therapy…
- Conditions
- Head and Neck Cancer, Body Image Disturbance, Body Image, Survivorship
- Trial name
- BRIGHT (NCT05442957)
- Testing
- BRIGHT, Attention Control
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Medical University of South Carolina
Acute Respiratory Distress Syndrome
Association Between the Level of EV-TF and the Occurence of Pulmonary Embolism in Patients With ARDS
In this study, 120 patients with Acute Respiratory Distress Syndrome (ARDS) will be included on a two years-period in an intensive care unit (Assistance Publique des Hôpitaux de Marseille, France).
- Trial name
- THROMBO-EVTF (NCT05855317)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
VExUS in Ards Patients and Association with AKI
A single-center prospective observational study will be conducted with the aim of determining the prevalence of venous congestion during ARDS using venous Doppler and the VExUS score.
- Trial name
- VEXAKI (NCT06805409)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer
Effectiveness of A Multi-Component Self-Management Intervention for Anxiety and Respiratory-Related Symptoms in Patients With Lung Cancer
The study aims to examine the effectiveness of M-RDSI (Mindfulness-Respiratory Distress Symptom Intervention) in Hong Kong (HK) Chinese patients with lung cancer (LC).
- Trial name
- NCT07782710
- Testing
- M-RDSI, RDSI, Usual Care
- Volunteers
- 189 people
- Sponsor
- The Hong Kong Polytechnic University
Relationship Conflict, Relationship Distress
OurRelationship-S: A Digital Relationship-Strengthening Program for Couples Experiencing Substance Misuse
This study tests the effectiveness of an online relationship program that has been tailored for couples in which one or both members are in recovery from substance misuse.
- Trial name
- NCT07159633
- Testing
- Online Couple Intervention
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- OurRelationship
Transfusion-Related Acute Lung Injury, ARDS, Human
Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples
Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusions. After a transfusion, TRALI develops in 0.08-15% of cases depending on the characteristics of the studied population.
- Trial name
- CURIE (NCT06444750)
- Testing
- Blood sample collection
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Septic Shock, Acute Respiratory Distress Syndrome
CytOSorb TreatMent Of Critically Ill PatientS Registry
Registry intended to provide a data repository and reporting infrastructure for the surveillance of CytoSorb device use in real-world critical care settings, and to serve as an objective, comprehensive, and scientifically-based…
- Conditions
- Septic Shock, Acute Respiratory Distress Syndrome, Trauma, Rhabdomyolysis
- Trial name
- COSMOS (NCT05146336)
- Testing
- CytoSorb
- Where
- 28 sites in Austria, Germany and 4 more
- Volunteers
- 3,000 people
- Sponsor
- CytoSorbents, Inc
Hemodialysis, Dialysis-Related Distress
Nurse-Led Dialysis Self-Management Program for Hemodialysis Distress
Hemodialysis patients may experience dialysis-related distress due to long-term treatment requirements, dietary and fluid restrictions, medication use, vascular access problems, dialysis-related symptoms, and psychosocial…
- Trial name
- NCT07747012
- Testing
- Nurse-Led Needs-Based Dialysis Self-Management Program, Routine Hemodialysis Care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kutahya Health Sciences University
Distress, Emotional, Depression, Anxiety
Training in Evidence-based Treatments in Psycho-Oncology
The goal of this research study is to train psychotherapists to administer individualized evidence-based psychotherapies in a cancer care setting to patients and caregivers with elevated levels of distress.
- Conditions
- Distress, Emotional, Depression, Anxiety, Fatigue, Pain
- Trial name
- NCT05674357
- Testing
- Individualized Evidence-Based Therapy in Cancer (Patients and Caregivers), Training in Individualized Evidence-Based Therapy in Cancer (Therapists)
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Massachusetts General Hospital
Psychosocial Distress, Cancer
Addressing Cancer-Related Distress Through Survivorship Care in Community Oncology
The goal of this study is to understand whether providing a structured survivorship care visit at the beginning of cancer treatment is associated with changes in distress and quality of life in adults with cancer receiving…
- Trial name
- NCT07673731
- Testing
- Structured Survivorship Visit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ellis Medicine
Anxiety, Distress, Emotional
Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers
The purpose of this research is to measure alterations in anxiety and brain activity associated with the use of an approved health device called Transauricular Vagal Nerve Stimulation (TaVNS) in distressed persons who work in a…
- Conditions
- Anxiety, Distress, Emotional, Effects of Vibration, Healthy
- Trial name
- fMRIVNS (NCT05132881)
- Testing
- Neuvana 2.0 Transcutaneous Auricular Vagal Nerve Stimulation (TaVNS), Waitlist Control, Healthy Controls: Substudy Group III
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Facial Palsy
Relationship Between Facial Palsy and Psychological Distress
The goal of this observational cross-sectional study is to investigate whether the severity of facial dysfunction is associated with psychological distress in patients with unilateral facial palsy.
- Trial name
- FNP-Psy (NCT07511140)
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Cairo University
Caregiver Stress, Caregiver Stress Syndrome
ACT Group for Family Caregivers of Stroke Survivors
The goal of this study is to evaluate the efficacy of group-based ACT intervention in improving the levels of psychological distress in caregivers of stroke survivors. The main questions it aims to answer are: 1.
- Conditions
- Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress
- Trial name
- NCT07528261
- Testing
- Group-based ACT Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Wright Institute
Psychological Distress, PTSD
Boosting Refugee Integration Through Psychological Intervention
Refugees and asylum seekers (RAS) face numerous stressors and adversities which put them at risk for developing mental health problems. However, access to adequate mental health care in host countries is limited.
- Conditions
- Psychological Distress, PTSD, Trauma, Common Mental Health Problems
- Trial name
- BRIGHT (NCT06776523)
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 1,200 people
- Sponsor
- University of Zurich