Clinical trials: Regional Anesthesia Block, active
Anesthesia, Postoperative Pain
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding.
- Conditions
- Anesthesia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT07712783
- Testing
- Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ondokuz Mayıs University
Post Operative Analgesia, Regional Anaesthesia
Comparison Between Paravertebral and Erector Spinal Block Efficacy in Robotic Thoracic Surgeries
The overall goal of this work is to find the preferred continues catheter- based thoracic block for patients who undergoing major ROBOTIC assisted thoracic surgery (Lobectomy, multiple segmental resection and thoracotomy).
- Conditions
- Post Operative Analgesia, Regional Anaesthesia, Pain After Surgery, Opioid Consumption
- Trial name
- TPVB vs ESP (NCT07782073)
- Testing
- Paravertebral Nerve Block, ESP block group
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Hemorrhoids, Postoperative Pain
Ultrasound-Guided Versus Landmark-Guided Pudendal Block for Post-Hemorrhoidectomy Pain
Hemorrhoid surgery is often followed by significant pain during the first few days after the operation. Pudendal nerve block is a pain-control technique that can help reduce discomfort after surgery.
- Conditions
- Hemorrhoids, Postoperative Pain, Pudendal Nerve Block
- Trial name
- NCT07889869
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Landmark-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Postoperative Pain, Hemidiaphragmatic Paresis
Combined Suprascapular and PECS I Blocks Versus Interscalene Block for Shoulder Arthroscopy
Shoulder arthroscopy can cause moderate to severe pain after surgery. An interscalene block is commonly used to reduce this pain, but it may temporarily weaken movement of the diaphragm on the treated side.
- Trial name
- NCT07852754
- Testing
- suprascapular nerve block, PECS I Block, Interscalene Brachial Plexus Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cansu Ofluoğlu
Laparoscopic Appendectomy
Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed
Laparoscopic appendectomies are the most common emergency surgeries performed in children. Despite being considered minimally invasive surgeries, they can result in substantial postoperative pain and 2 of 3 patients require…
- Trial name
- NCT06945263
- Testing
- Rectus Sheath Block, Local Anesthetic at the Umbilical Port Site, Intravenous Dexamethasone
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Pain Management, Regional Anesthesia
Revision of Deep Brain Stimulator in Patients With Parkinson's Disease
Parkinson's disease is a chronic and progressive neurodegenerative disease that affects the central nervous system, particularly impairing movement control.
- Conditions
- Pain Management, Regional Anesthesia, Deep Brain Stimulation, Parkinsons Disease
- Trial name
- NCT07176494
- Testing
- Patients who underwent surgery under general anesthesia, Patients who underwent surgery under regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Post Operative Pain, Analgesia
Evaluation of Postoperative Pain Control in Ear Surgery
Middle ear surgery is the most popular procedure in ear, nose and throat surgery. Increased sympathetic stimulation after surgery can activate the sympathetic system, causing hypertension and increased heart rate.
- Trial name
- NCT06869967
- Testing
- Auricularis Magnus Nerve Block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kocaeli University
Pain Management
Local Anesthesia for Facial Fractures
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics.
- Trial name
- LAFF (NCT06429501)
- Testing
- Bupivacaine/Epinephrine, Saline
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Quality of Recovery After Mastectomy, Serratus Anterior Plane Block
Timing of Serratus Anterior Plane Block in Mastectomy Surgery
Postoperative pain following mastectomy may adversely affect early mobilization, patient comfort, and overall quality of recovery.
- Conditions
- Quality of Recovery After Mastectomy, Serratus Anterior Plane Block, Postoperative Pain, Mastectomy
- Trial name
- NCT07661212
- Testing
- Ultrasound-Guided Serratus Anterior Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cutaneous Sensory Blockade
Effects of Injection Volume and Site on Sensory Distribution After Rectus Sheath Block
This randomized controlled study aims to evaluate the effects of local anesthetic injection volume and injection site on cutaneous sensory distribution following ultrasound-guided rectus sheath block (RSB).
- Trial name
- RSB-SENSE (NCT07876297)
- Testing
- Ultrasound-Guided Upper Rectus Sheath Block (20 mL), Ultrasound-Guided Upper Rectus Sheath Block (30 mL), Ultrasound-Guided Middle Rectus Sheath Block (20 mL)
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Chiang Mai University
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Hernia, Umbilical, Clonidine
Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery.
- Conditions
- Hernia, Umbilical, Clonidine, Pain, Postoperative, Ambulatory Surgical Procedures
- Trial name
- NCT07062497
- Testing
- Rectus Sheath Block, Rectus Sheath Block with Clonidine
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Smoking, Cigarette, Regional Anesthesia
Impact of Smoking on Ultrasound-Guided Infraclavicular Brachial Plexus Block Onset and Duration
The present study will be conducted involving 40 patients aged 18-65 years with ASA physical status I and II, scheduled for acute or elective hand or forearm surgery under the lateral infraclavicular block.
- Trial name
- NCT06755229
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Postoperative Pain After Breast Augmentation Surgery, Postoperative Analgesia
Effect of Adding Ultrasound-Guided PECS II Block to Standard Multimodal Analgesia in Breast Augmentation Surgery
This randomized, controlled clinical study will evaluate the effect of an ultrasound-guided PECS II block on postoperative pain control in patients undergoing elective augmentation mammoplasty.
- Trial name
- NCT07879053
- Testing
- Ultrasound-Guided PECS II Block, Standard multimodal analgesia
- Volunteers
- 50 people
- Sponsor
- Ergun Gunduz
Aortic Valve Stenosis
RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation
Open-label, 2 x 2 factorial, prospective, randomized, national, multicenter study to compare latest-generation self-expanding valves and a minimalist approach versus standard of care in transcatheter aortic valve implantation.
- Trial name
- DOUBLE-CHOICE (NCT05036018)
- Testing
- ACURATE neo2, minimalist approach, CoreValve Evolut Pro, Pro+ and FX
- Where
- 10 sites in Germany
- Volunteers
- 836 people
- Sponsor
- Leipzig Heart Science gGmbH
Gender Affirming Surgery, Mastectomy
Gender Affirming Mastectomy Analgesia Rial
Introduction: Optimizing pain management after gender-affirming mastectomy (removal of breast tissue, aka top surgery) surgery is important for recovery and minimizing opioid use.
- Conditions
- Gender Affirming Surgery, Mastectomy, Acute Pain
- Trial name
- GAMA (NCT07861165)
- Testing
- Paravertebral (single injection), Wide local infiltration
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Nova Scotia Health Authority
Carpal Tunnel Syndrome
Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block
Carpal tunnel syndrome (CTS) is the most commonly appearing entrapment neuropathy of the upper extremity. Treatment options include both non-operative and operative methods.
- Trial name
- PERSONNEL (NCT05372393)
- Testing
- Local infiltration anaesthesia in carpal tunnel release, Distal median nerve block with local infiltration anaesthesia in carpal tunnel release
- Where
- Finland
- Volunteers
- 118 people
- Sponsor
- Kuopio University Hospital
ENT Cancers
Evaluation of the Superficial Cervical Plexus Block in Oncological Throat and Neck Surgery
This national, prospective, multicenter, randomized study aims to reduce the amount of intravenous morphine (titration + PCA morphine) during the first 24 postoperative hours via a locoregional anesthesia technique in patients…
- Trial name
- BCS-ORL (NCT07110857)
- Testing
- Cervical plexus block with 0.2 % Naropeine
- Where
- 7 sites in France
- Volunteers
- 346 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postoperative Pain Management, Penile Surgery-Related Pain
Anatomical Measurements of Pudendal Nerve Block in Children
This prospective observational study aims to investigate the relationship between anatomical parameters-specifically the distance from the anus to the needle insertion point and the depth required to reach the pudendal…
- Trial name
- NCT07348029
- Testing
- Neurostimulation-Guided Pudendal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa