Clinical trials: Refractive Surgery
Cataract, Presbyopia
Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens
The main goal of this study is to evaluate real-world visual outcomes, rotational stability, and patient reported visual disturbances with a non-diffractive extended vision presbyopia and astigmatism correcting intraocular lens…
- Conditions
- Cataract, Presbyopia, Corneal Astigmatism
- Trial name
- NCT04652037
- Testing
- Acrysof IQ Vivity Toric Extended Vision Intraocular Lens Implantation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Astigmatism
Rotational Stability After Nanoflex Collamer Toric Intraocular Lens Implantation in Astigmatic Patients
This study aims to assess the rotational stability of the new collameric Nanoflex toric intraocular lens (T-IOL) by STAAR inserted in astigmatic patients after cataract surgery.
- Trial name
- T-IOL (NCT02412215)
- Testing
- Phacoemulsification with toric Nanoflex IOL implantation, NanoFlex toric Intraocular Lens
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Myopia
Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel
The purpose of this study is to: 1. evaluate the safety and efficacy of conventional PRK in U.S. Army personnel who have naturally occurring myopia with or without astigmatism. 2.
- Trial name
- NCT00412568
- Testing
- Photorefractive Keratectomy (PRK)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Cataract, Refractive Errors
Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery
The two main objectives of this study are to demonstrate safety and effectiveness of implanting the PanOptix Trifocal IOL in patients who have had previous myopic Lasik.
- Trial name
- NCT04698278
- Testing
- PanOptix Trifocal Intraocular Lens
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Parkhurst NuVision Clinical Research LLC
Myopia
Does Pupil Size Matters in Refractive Surgery?
To determine the influence of pupil size in refractive surgery. If any influence exist.
- Trial name
- NCT01678729
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Astigmatism
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
This study aims to evaluate the safety and effectiveness of femtosecond laser arcuate corneal relaxing incisions (AK) combined with Light Adjustable Lens (LAL) implantation for correcting pre-existing corneal astigmatism in…
- Trial name
- NCT07140653
- Testing
- Femto arcs, Light Adjustable Lens (LAL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Center For Sight
Refractive Surgery
Topography Guided LASIK by Different Protocols for Treatment of Astigmatism
Background and Rationale: LASIK has been among the highest satisfaction rates of surgical procedures, ranging from 82%-98%. Different ablation profiles have been developed over the years.
- Trial name
- NCT03597906
- Testing
- topography guided ablation, manifest refraction, full topography modified refraction
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Refractive Surgery
Risk Factors for Progressive Suction Loss in Corneal Refractive Surgery
The goal of this Prospective observational studiesis to Characteristics of progressive suction loss.
- Trial name
- NCT06264804
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Yifeng Yu
Refractive Errors, Cataract
Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome
To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes…
- Trial name
- NCT04783909
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Cataract, Myopia
Measurement of Antioxidant Activity on Postoperative Inflammation in Patients Undergoing Ophthalmic Surgery
This trial hypothesized that novel laser refractive surgery techniques (PRK, LASIK, SMILE) or laser-assisted cataract surgery (FLACAS) could suppress postoperative inflammation and improve recovery in patients by reducing…
- Trial name
- NCT05905237
- Testing
- Cataract surgery, Femtosecond-LASIK, SMILE
- Where
- 2 sites in Taiwan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Unstable Corneas
Corneal Cross-Linking Comparing Variables
The purpose of this study is to evaluate the Safety and Efficacy of Corneal Cross Linking in a Continuous Beam versus Pulsed Treatments across epithelium on and epithelium off surfaces.
- Trial name
- NCT02095730
- Testing
- Epithelium-On Riboflavin, Epithelium-Off Riboflavin, UV Light - Continuous Beam
- Where
- 16 sites in United States
- Volunteers
- 500 people
- Sponsor
- Crowd Health Research, LTD
Hyperopia
Photorefractive Keratectomy (PRK) for Hyperopia After Radial Keratotomy
To assess the efficacy, predictability, stability and safety of corneal wavefront-guided photorefractive keratectomy (PRK) for correcting hyperopia and astigmatism after radial keratotomy (RK).
- Trial name
- NCT00917657
- Testing
- Photorefractive keratectomy
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo
Aphakia, Astigmatism
Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL)
The purpose of this Post-Market Clinical Follow-up (PMCF) study is to describe the long-term safety and performance of the AcrySof IQ PanOptix IOL toric and non-toric models in subjects bilaterally implanted with these IOLs for 3…
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT06166901
- Testing
- AcrySof IQ PanOptix IOL Toric, AcrySof IQ PanOptix IOL Non-Toric
- Where
- 7 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Alcon Research
Astigmatism
Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism
The investigational enVista IOL, Model MX60Tis equipped with toric optics and axis marks on the posterior surface to minimize the possibility of surgically induced astigmatism.
- Trial name
- NCT01852084
- Testing
- enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Surgery, Myopia; Refractive Error
Clinical Study of SMILE 4.0-VISULYZE in Correcting Refractive Errors
The aim of this study is to further optimize the surgical input parameters for patients undergoing Small Incision Lenticule Extraction (SMILE) using the regression model established by the SMILE 4.0-VISULYZE system, thereby…
- Trial name
- NCT06982807
- Testing
- Group 4.0-VISULYZE, traditional group
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Affiliated Hospital of Nantong University
Astigmatism
Astigmatism Management in Cataract Surgery With the AcrySof Toric Intraocular Lens
The purpose of this study is to determine if Toric intraocular lens implantation in cataract surgery is a more efficient and cost-effective treatment of astigmatism than Monofocal intraocular lens implantation.
- Trial name
- NCT01075542
- Testing
- AcrySof Toric intraocular lens, model SN60TT, AcrySof Monofocal IOL, model SN60AT
- Where
- 3 sites in Netherlands
- Volunteers
- 86 people
- Sponsor
- Maastricht University Medical Center
Laser Corneal Surgery
Corneal Biomechanics With Hydration in Normal and LASIK Eyes
The research will utilize LASIK and non-LASIK populations to analyze the biomechanical differences between these corneas.
- Trial name
- NCT01183702
- Testing
- LASIK surgery, No Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Deb Grzybowski
Cataract, IOL
Visual Outcomes With a Trifocal IOL in Subjects With Open-angle Glaucoma
This study will examine the visual outcomes of subjects undergoing cataract surgery and minimally invasive glaucoma surgery with the implantation of a trifocal intraocular lens.
- Conditions
- Cataract, IOL, Glaucoma, Open-Angle
- Trial name
- NCT04619654
- Testing
- Cataract surgery with implantation of trifocal IOL combined with trabecular scaffold
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vold Vision P.L.L.C