Clinical trials: Refractive Error Correction
Hyperopia
Hyperopia Correction Using the NTK Optimal Keratoplasty (Opti-K) System
The purpose of this U.S. Clinical Trial on treatment of sighted eyes is to investigate the safety and effectiveness of optimal keratoplasty (Opti-K™) treatments for hyperopia correction using the NTK Enterprises (NTK) Opti-K…
- Trial name
- NCT01028937
- Testing
- Optimal Keratoplasty
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NTK Enterprises, Inc.
Presbyopia, Refractive Error
Visual Performance of Prototype Contact Lens Designs
The aim of this study is to assess the visual performance of prototype soft contact lens designs compared to a commercially available contact lens
- Trial name
- NCT02193555
- Testing
- Etafilcon A, Senofilcon A
- Where
- Australia
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
Presbyopia, Ametropia
Clinical Trial With Artiflex Presbyopic (Artiplus)
The purpose of this clinical trial is to evaluate the effectiveness and safety of the multifocal Artiflex Presbyopic (Artiplus) intraocular lens.
- Conditions
- Presbyopia, Ametropia, Refractive Errors, Myopia
- Trial name
- NCT04632784
- Testing
- Artiflex Presbyopic (Artiplus) implantation
- Where
- 7 sites in South Korea, Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser on an Implanted Intraocular Lens
This is a prospective non-randomized patient controlled single center study which is designed to evaluate the clinical outcomes of the treatment of an implanted intraocular lens using a low-energy femtosecond laser for refractive…
- Trial name
- NCT07473557
- Testing
- Device
- Where
- Panama
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Refractive Errors, Myopia
Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn continuously for up to 1 week.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04403542
- Testing
- Lehfilcon A contact lens, Comfilcon A contact lens
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Presbyopia
Safety and Efficacy of an Intrastromal Transform™ Corneal Allograft (TCA) for Presbyopia Correction
The objective of this clinical study is to evaluate the safety and effectiveness of intrastromal implantation of the Allotex TransForm corneal allograft (TCA) for improving near vision in presbyopic subjects.
- Trial name
- NCT03671135
- Testing
- TCA Intrastromal Inlay
- Where
- 4 sites in Belgium, Ireland and 1 more
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Allotex, Inc.
Astigmatism
Evaluation Study on Corneal Lens for Vision Correction
The objective of this study is to evaluate the fitting and visual outcomes of Nexis Lens, made of silicone commonly used in the contact lens industry, on healthy eye with or without astigmatism.
- Trial name
- NCT02053688
- Testing
- Astigmatic Correction Lens (Nexis ACCL lenses), Toric Soft Contact Lenses
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Refractive Errors
Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens
The purpose of this clinical study is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT04422990
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
New Treatment Algorithm to Reduce Spherical Aberration After LASIK Correction for Myopia
The purpose of this clinical trial is to demonstrate that treatments generated by an investigational algorithm reduces spherical aberration compared to currently available iDesign treatments.
- Trial name
- NCT01988415
- Testing
- VSS-Rx1 OPM vs Commercial iDesign Treatment
- Where
- Colombia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Presbyopia, Myopia
Presbyopic Phakic Intraocular Lens for Myopia Correction
This is a prospective single-center study of implantations of the presbyopic version of phakic intraocular lens IPCL (EyeolUK, United Kingdom).
- Trial name
- NCT03836898
- Testing
- Presbyopic posterior chamber phakic intraocular lens IPCL
- Where
- Czechia
- Volunteers
- 10 people
- Sponsor
- Gemini Eye Clinic
Hyperopia
Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors
Demonstrate that wavefront-guided LASIK using measurements from the iDesign System is safe and effective for the treatment of Hyperopia.
- Trial name
- NCT01675479
- Testing
- LASIK correction of hyperopic refractive errors
- Where
- 9 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Hyperopia and Myopia
Evaluation of a New Laser Refractive Vision Correction Using the TENEO™ 317 Model 2
Prospective, post market clinical follow up study with a three months postoperative follow up to evaluate the visual and refractive outcomes of OCTAVIUS treatment when used as intended.
- Trial name
- NCT06997003
- Testing
- Anterior treatment mode, Total treatment mode
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- Bausch & Lomb GmbH
Myopia, Refractive Errors
A Clinical Trial to Evaluate the Vision Correction Safety and Efficacy of DSiHy Silicone Hydrogel Soft Contact Lens
This is a prospective, randomized, double-blind, parallel, active-controlled, multi-center clinical study. The purpose is to evaluate the safety and effectiveness wearing "DSiHy Silicone Hydrogel Soft Contact Lens".
- Trial name
- NCT06716372
- Testing
- DSiHy Silicone Hydrogel Soft Contact Lens, Daily Silicone Hydrogel Contact Lenses (oB)
- Where
- 3 sites in Taiwan
- Volunteers
- 134 people
- Sponsor
- Visco Vision Inc.
Stable Myopic Refractive Error, With or Without Astigmatism
Prospective S&E Study of Wavefront-guided PRK for Myopia With iDesign Advanced Wavescan Studio™ System and Star S4 IR™
Prospective, multicenter, bilaterally-treated, open-label, non-randomized clinical trial.
- Trial name
- NCT02675751
- Testing
- STAR S4 IR laser with iDesign
- Volunteers
- 167 people
- Sponsor
- Abbott Medical Optics
Myopia, Astigmatism
Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser
The objective of this clinical trial is to evaluate the safety and effectiveness of the Carl Zeiss Meditec VisuMax™ Femtosecond Laser lenticule removal procedure for the reduction or elimination of myopia from ≥ -1.00 D to ≤…
- Trial name
- NCT02430428
- Testing
- Carl Zeiss Meditec VisuMax Femtosecond Laser
- Where
- 5 sites in United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Refractive Errors
Clinical Performance of Two Daily Disposable Contact Lenses - Study 1
The purpose of this study is to evaluate end of day (EOD) visual acuity (VA) at distance when wearing Precision1™ contact lenses compared to Acuvue® Moist contact lenses.
- Trial name
- NCT03969290
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
CLEAR Procedure in Myopia and Astigmatism - Registry Study
Multicenter, prospective, single-arm, observational, non-interventional post market clinical investigation (registry study) with the overall objective to assess safety and performance of CLEAR in a real world setting.
- Trial name
- NCT05484531
- Testing
- CLEAR
- Volunteers
- 150 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Hyperopia
Safety and Effectiveness Study of the MEL 80 Excimer Laser Using LASIK in the Treatment of Hyperopia
The purpose of this study is to determine whether the MEL 80 Excimer Laser is effective in the treatment of hyperopia, when used as part of the Laser In Situ Keratomileusis (LASIK) procedure.
- Trial name
- NCT00762281
- Testing
- MEL 80 Hyperopic LASIK Treatment
- Where
- 6 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Presbyopia
An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1)
This is a 4-visit, multi-center, randomized, double-masked, vehicle-controlled study evaluating the safety and efficacy of CSF-1 in the temporary correction of presbyopia.
- Trial name
- NEAR-1 (NCT04599933)
- Testing
- CSF-1, Vehicle
- Where
- 17 sites in United States
- Volunteers
- 309 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Cataract, Corneal Astigmatism
Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism
The objectives of the clinical investigation are to determine the safety and performance of the RayOne EMV Toric (Model RAO210T) following unilateral implantation and approximately 6 months (120 to 180 days) of post-operative…
- Trial name
- NCT05985304
- Testing
- RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Rayner Intraocular Lenses Limited