Clinical trials: Refractive Error
Myopia
MiSight 1 Day Safety Post-Approval Study
The purpose of this post-approval study is to confirm the safety of daily disposable soft contact lens wear among the intended patient population for the MiSight 1 Day lens in the US.
- Trial name
- NCT05285527
- Testing
- MiSight 1 Day
- Where
- 50 sites in United States, Canada
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Asthenopia, Visual Fatigue
Impact of Red Light Therapy on Alleviating Visual Fatigue in Presbyopes
Visual fatigue, or asthenopia, occurs when visual demands exceed the capacity of the visual system, leading to various ocular discomfort and systemic symptoms.
- Conditions
- Asthenopia, Visual Fatigue, Presbyopia
- Trial name
- NCT06745661
- Testing
- RLRL device
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- The Hong Kong Polytechnic University
Refractive Error, Myopia
Clinical Comparison of DDT2 Contact Lens and a Daily Disposable Contact Lens - Study 1
The purpose of this study was to evaluate visual acuity at distance when wearing DDT2 contact lenses compared to Acuvue Moist contact lenses.
- Trial name
- NCT03888469
- Testing
- Verofilcon A contact lenses, Etafilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Alcon Research
Myopia
Preservative-free Topical Anesthetics for Post-PRK Pain
The goal of this interventional comparative study is to assess the efficacy and safety of a novel regimen of preservative-free unit-dose topical anesthetics for controlling early postoperative pain following single-step…
- Trial name
- NCT05733741
- Testing
- Preservative-free Benoxinate hydrochloride 0.4% (Benoxidia unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt), Preservative-free Sodium hyaluronate 0.2% (Polyfresh unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt).
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myopia
The Clinical Performance of the Biofinity Contact Lens (Comfilcon A) With Two Lens Care Systems
This will be a controlled and randomized, single-masked, crossover study in which 48 subjects will use the Biofinity Contact Lens (comfilcon A) with each of the two lens care products ('solutions'), (Synergi and Biotrue…
- Trial name
- NCT02510820
- Testing
- comfilcon A, Synergi, Biotrue
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- CooperVision, Inc.
Presbyopia
DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance
The purpose of this study is to evaluate the visual performance of DACP MF and PROCLEAR 1D MF daily disposable contact lenses in an established presbyopic population.
- Trial name
- NCT02403180
- Testing
- DACP MF, PROCLEAR 1D MF
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Myopia, Left Eye
Short Term Refractive and Ocular Parameter Changes After Topical Atropine
In order we had designed a prospective clinical trial. Spherical equivalent refractive error (SER), axial length (AL), mean keratometric value (Mean-K), anterior chamber depth (ACD), and intraocular pressure (IOP) were measured…
- Trial name
- NCT03839888
- Testing
- 0.125% Atropine
- Volunteers
- 96 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Myopia
Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study
This project aims to study the effects of treatment characteristics on myopia control in orthokeratology by investigating the effects of modified treatment zone by reducing the lens back optic zone diameter on the effect of…
- Trial name
- NCT03191942
- Testing
- Modified ortho-k lenses, Ortho-k lenses
- Where
- 2 sites in Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Astigmatism
Laser Correction of Astigmatism Using Vector Analysis
To determine the effectiveness of correcting astigmatism by laser refractive surgery by a vectorial astigmatism outcome analysis that uses 3 fundamental vectors : target induced astigmatism vector ( TIA) , surgically induced…
- Trial name
- NCT04913883
- Volunteers
- 50 people
- Sponsor
- Assiut University
Myopia
Effect of Preoperative Pupil Size on Quality of Vision After Wavefront-Guided LASIK
The purpose of this study is to evaluate whether the size of the pupil has an effect on quality of vision in patients undergoing LASIK surgery.
- Trial name
- NCT00889941
- Testing
- LASIK
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Refractive Errors, Accomodation
Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
This study is exploratory and examines whether the refraction results obtained from a novel optical device yields results similar to the ophthalmic refraction measurements obtained from an autorefractor in children.
- Conditions
- Refractive Errors, Accomodation, Diagnostic Self Evaluation
- Trial name
- NCT04955379
- Testing
- EQ103
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia
the Clinical Performance of the Oxysoft Daily Disposable Silicone Hydrogel Soft Contact Lens
The objective of this study is to demonstrate that the OxySoft silicone hydrogel soft contact lens could be prescribed as a supportive care for myopes.
- Trial name
- NCT03934788
- Testing
- oxysoft (olifilcon C), Si-Hy (olifilcon B)
- Where
- 3 sites in Taiwan
- Volunteers
- 36 people
- Sponsor
- Visco Vision Inc.
Myopia
Daily Disposable Contact Lens Tear Film Study
The purpose of this study was to evaluate the pre-lens tear film stability of a new CE-marked daily disposable contact lens as compared to a commercially available daily disposable contact lens.
- Trial name
- NCT01473160
- Testing
- delefilcon A contact lens, narafilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- CIBA VISION
Presbyopia, Near Vision
Validation of an Activities-of-daily-living Framework at Different Light Conditions
Primary objective of this study is the construction and validation of an experimental environment for the simulation of a variety of near- and intermediate-vision activities of daily living (ADLs) in different combinations of…
- Conditions
- Presbyopia, Near Vision, Reading, Daily Activities
- Trial name
- NCT05005624
- Testing
- ADL performance
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia
Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia.
The purpose of the study is to quantify the effectiveness of CooperVision MiSight® (omafilcon A) soft (hydrophilic) contact lens in slowing the rate of progression of juvenile-onset myopia.
- Trial name
- NCT01917110
- Testing
- omafilcon A, Spectacle
- Where
- Spain
- Volunteers
- 79 people
- Sponsor
- CooperVision, Inc.
Hyperopia
Hyperopic LASIK With Crosslinking Versus Standard LASIK
Analysis corneal and refractive stability of hyperopic laser-assisted in situ keratomileusis (LASIK) with and without concurrent prophylactic high-fluence cross-linking (CXL).
- Trial name
- NCT03224013
- Testing
- LASIK
- Volunteers
- 25 people
- Sponsor
- Minia University
Presbyopia
Safety & Efficacy of the Laser Scleral Microporation Procedure
A new minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment
- Trial name
- NCT05068479
- Testing
- Bilateral Laser Scleral Microporation procedure
- Where
- Panama
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- ACE Vision Group, Inc.
Aberration, Corneal Wavefront
Immediate Effects of Lipid-Based and Non-Lipid Artificial Tears on Corneal Aberrations
This study evaluates the immediate effects of two types of artificial tear formulations on corneal aberrations in a healthy population.
- Trial name
- ILEACT (NCT06784661)
- Testing
- Lipid-Based Artificial Tear, Non-Lipid Artificial Tear
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Seville
Myopia, Myopia Progression
Myopia Control Spectacle Lens Cessation Study
To quantify myopic progression (cycloplegic spherical equivalent refraction - cSER) following the cessation of use of specific spectacle lenses.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- BIRCH (NCT05893979)
- Testing
- Spectacle Lenses
- Where
- 8 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Clinical Evaluation of Two Daily Disposable Lenses in a Population of Daily Disposable (DD) Lens Wearers
The purpose of this study is to evaluate the performance of two daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT00958828
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens
- Volunteers
- 178 people
- Sponsor
- CIBA VISION