Clinical trials: Refractive Error
Myopia
A Study to Evaluate a Modified Contact Lens
This study is being conducted to evaluate the product performance of SofLens daily disposable contact lenses packaged in an investigational Test solution versus SofLens daily disposable contact lenses packaged in the currently…
- Trial name
- NCT01391364
- Testing
- SofLens in investigational solution, SofLens in currently marketed solution
- Where
- United States
- Volunteers
- 438 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors
Measurement of Refractive SE Following Implantation of LS313 MF30 IOL
This Study determines the most precise method for measuring post-operative refraction following implantation of the asymmetric multifocal LS-313 MF30 comparing the results of Refraction of the different Autorefractor Keratometers…
- Trial name
- NCT03292614
- Testing
- Measurements of the postoperative refraction
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Myopia
Vistakon Investigational Lens Worn as a Single Use Daily Wear
This study is intended to show that the investigational contact lens is clinically equivalent to a currently approved contact lens, when worn as single-use on a daily basis.
- Trial name
- NCT01031004
- Testing
- narafilcon B, etafilcon A
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Clinical Assessment of the Hemacopolymer Daily Disposable Limbal Ring Soft Contact Lens
This purpose of this study is to compare the clinical performance and subjective acceptance of two different daily disposable limbal ring lenses.
- Trial name
- NCT01965262
- Testing
- Hema-copolymer Lens, etafilcon A Lens
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
On-Eye Evaluation of Contact Lens Axis Location
The purpose of this study was to evaluate the axis location of toric contact lenses after 3 minutes of wear. During this 1-visit study, each participant wore 3 pairs of study lenses of various design iterations (2-87-1, 2-87-2…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT02100410
- Testing
- Delefilcon A toric contact lens T1, Delefilcon A toric contact lens T2, Delefilcon A toric contact lens T3
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Myopia
Clinical Evaluation of an Investigational Soft Contact Lens
The purpose of this 4-week dispensing trial is to evaluate and compare an investigational soft contact lens worn on a daily disposable basis with three other soft contact lenses also worn on a daily disposable basis.
- Trial name
- NCT01254747
- Testing
- Delefilcon A contact lens, Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX), Nelfilcon A contact lens (DAILIES AquaComfort Plus)
- Where
- 2 sites in United States, Germany
- Volunteers
- 130 people
- Sponsor
- CIBA VISION
Hyperopia
Pilot Dispensing Evaluation of a Plus Power Lens
The purpose of this study is to compare the performance of the ACUVUE® ADVANCE® Plus lenses against ACUVUE® ADVANCE® lenses in the plus power parameters.
- Trial name
- NCT01228591
- Testing
- Acuvue Advance Plus, Acuvue Advance
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study was to compare the clinical performance of two monthly toric silicone hydrogel contact lenses in habitual wearers, when worn for 1-month each.
- Trial name
- NCT05933772
- Testing
- Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Aphakia, Presbyopia
Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population
The primary objective of this clinical study is to assess the clinical performance of the PanOptix IOL in a Chinese population.
- Trial name
- NCT04755231
- Testing
- AcrySof IQ PanOptix Presbyopia Correcting IOL, Cataract surgery
- Where
- 9 sites in China
- Volunteers
- 181 people
- Sponsor
- Alcon Research
Presbyopia
Clinical Evaluation of Two New Silicone Hydrogel Multifocal Products
The objective of this trial is compare the visual performance, ratings, and preference of two multifocal, soft contact lenses.
- Trial name
- NCT00909792
- Testing
- Lotrafilcon B, Senofilcon A
- Volunteers
- 259 people
- Sponsor
- CIBA VISION
Myopia
A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)
The purpose of this study was to demonstrate that current successful fulltime daily wear soft contact lens wearers using competitive multi-purpose solutions will note improved comfort when using OPTI-FREE RepleniSH®.
- Trial name
- NCT00772707
- Testing
- Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses.
- Trial name
- NCT01309893
- Testing
- Investigational Lens, Air Optix Aqua lens
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Four Week Performance Comparison Between Two Commercially Available Silicone Hydrogel Lenses
The purpose of this study is to compare the performance of two commercially marketed contact lenses when worn for up to 4 weeks in a daily wear modality.
- Trial name
- NCT01300767
- Testing
- Lotrafilcon B contact lens (AIR OPTIX® AQUA), Balafilcon A contact lens (PureVision® 2), Contact lens solution (Clear Care®)
- Volunteers
- 75 people
- Sponsor
- CIBA VISION
Ametropia
Evaluation of Investigational (Frequent Replacement) FRP Lens for Daily Wear
The purpose of the study is to compare the investigational contact lens to a marketed contact lens. The study results were not used for design validation of investigational contact lens,
- Trial name
- NCT02362724
- Testing
- Sapphire, Pearl
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Clinical Validation of Biofinity Toric MTO (Made To Order) Lenses
The study hypothesis is there is no difference in the clinical performance between the test and control lenses, in particular in lens stability, toric mislocation, comfort ratings and anterior segment ocular health findings.
- Trial name
- NCT02185105
- Testing
- comfilcon A MTO, comfilcon A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Myopia
A Study to Assess the Safety and Efficacy of a Daily Disposable Contact Lens
The objective of this study is to evaluate the safety and efficacy of the Bausch \& Lomb daily disposable tint contact lens (Test) compared to a currently marketed daily disposable cosmetic tint contact lens (Control).
- Trial name
- NCT01130974
- Testing
- Bausch & Lomb contact lens, Marketed daily disposable contact lens
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors
Clinical Evaluation of a Daily Wear Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to demonstrate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT03920280
- Testing
- LID015385 contact lenses, Comfilcon A soft contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Myopia
The Clinical Comparison of Narafilcon A and Stenfilcon A Contact Lenses
This study aims to compare the clinical performance and subjective acceptance of the narafilcon A lens with the stenfilcon A lens when used on a daily wear, daily disposable basis.
- Trial name
- NCT02920970
- Testing
- narafilcon A, stenfilcon A
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Trial of Several Contact Lenses in Extended Wear
The study is to clinically evaluate currently marketed contact lenses when used in an extended wear modality of up to seven days/six nights.
- Trial name
- NCT00762788
- Testing
- senofilcon A, lotrafilcon A, lotrafilcon B
- Where
- India
- Volunteers
- 350 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION