Clinical trials: Refractive Assessment
Refractive Errors
Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens
The purpose of this clinical study is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in a daily wear modality.
- Trial name
- NCT04422990
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Spherical Contact Lenses
This study aims to compare the short-term clinical performance of the three contact lenses (Methafilcon A IV, Ocufilcon B 1-day and Omafilcon A 1-day daily disposable).
- Trial name
- NCT03235115
- Testing
- Methafilcon A IV, Ocufilcon B, Omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
A Study to Evaluate a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses.
- Trial name
- NCT01309893
- Testing
- Investigational Lens, Air Optix Aqua lens
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Clinical Evaluation of Two Monthly Replacement Silicone Hydrogel Contact Lenses
The purpose of this study is to evaluate differences in the comfort at the end of the month between Air Optix® lenses versus Biofinity® lenses in habitual daily wear symptomatic soft contact lens wearers.
- Trial name
- NCT01629693
- Testing
- Lotrafilcon B contact lenses, Comfilcon A contact lenses
- Volunteers
- 398 people
- Sponsor
- Alcon Research
Astigmatism
Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism
The investigational enVista IOL, Model MX60Tis equipped with toric optics and axis marks on the posterior surface to minimize the possibility of surgically induced astigmatism.
- Trial name
- NCT01852084
- Testing
- enVista® One-Piece Hydrophobic Acrylic Toric IOL, enVista control lens
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error
Clinical Assessment of DAILIES TOTAL1® (DT1) Multifocal
The purpose of this study is to evaluate DAILIES TOTAL1® Multifocal (DTl MF) contact lenses in current multifocal contact lens wearers with symptoms of end of day discomfort compared to their habitual multifocal contact lens…
- Trial name
- NCT02871375
- Testing
- Delefilcon A multifocal contact lenses, Habitual multifocal contact lenses
- Volunteers
- 170 people
- Sponsor
- Alcon, a Novartis Company
Presbyopia
A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens
The objective of this study is to evaluate the product performance of an investigational multifocal low add soft contact lens.
- Trial name
- NCT01539694
- Testing
- LD118033 contact lens, PureVision multifocal contact lens
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia, Refractive Error
DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance
The purpose of this study is to evaluate the visual performance of DAILIES® Aqua Comfort Plus® (DACP) MF contact lens using new objective measurements.
- Trial name
- NCT02235831
- Testing
- Nelfilcon A MF contact lenses (DACP MF), Nelfilcon A single vision contact lenses (DACP)
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Refractive Error
Clinical Evaluation of the Safety and Efficacy of FID 120947A
The purpose of this study is to evaluate the safety and efficacy of FID 120947A in soft contact lens wearers of Japanese ethnicity.
- Trial name
- NCT02771145
- Testing
- FID 120947A contact lens disinfecting solution, Soft contact lenses (SCL), SCL preservative solution
- Where
- Japan
- Volunteers
- 91 people
- Sponsor
- Alcon Research
Myopia, Ametropia
Clinical Evaluation of the Safety and Efficacy of a New Multifocal Contact Lens
The purpose of this study was to demonstrate substantial equivalence of the new DAILIES® AquaComfort Plus® Multifocal (DACP MF) contact lens to the commercially available Focus® DAILIES® Progressives (FDP) contact lens.
- Conditions
- Myopia, Ametropia, Presbyopia, Refractive Error
- Trial name
- NCT01797783
- Testing
- Nelfilcon A multifocal contact lens with comfort additive, Nelfilcon A multifocal contact lens
- Volunteers
- 83 people
- Sponsor
- Alcon Research
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Myopia
Performance Evaluation of a New Daily Disposable Silicone Hydrogel Lens
The purpose of this study was to compare a new daily disposable, silicone hydrogel contact lens to marketed daily disposable, silicone hydrogel contact lenses.
- Trial name
- TUNGSTEN (NCT01371552)
- Testing
- delefilcon A contact lens, filcon II 3 contact lenses, narafilcon A contact lenses
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- CIBA VISION
Myopia
Clinical Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens
The purpose of this study is to assess the clinical performance of an investigational contact lens over 30 days of daily wear.
- Trial name
- NCT04476784
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Alcon Research
Refractive Error
Formula Identification (FID) 114657 in Contact Lens Wearers
The purpose of this study is to evaluate the thickness of the pre-lens tear lipid layer after 2 hours of lens wear with use of FID 114657 compared to saline control.
- Trial name
- NCT02293538
- Testing
- FID 114657 eye drops (10 ml), Saline control eye drops (15 ml), Habitual contact lenses
- Volunteers
- 234 people
- Sponsor
- Alcon Research
Myopia
Clinical Evaluation of Daily Disposable Contact Lenses
The objective of the study is to compare the overall subjective preference of filcon II 3 daily disposable silicone hyrogel contact lenses compared to etafilcon A and nelfilcon A daily disposable conventional hydrogel contact…
- Trial name
- NCT02097030
- Testing
- filcon II 3, etafilcon A, nelfilcon A
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision, Inc.
Nearsightedness
Vault Evaluation After ICL Implantation
The purpose of this study is to evaluate the lens vault after implantation of an implantable collamer lens (ICL). The ICL is designed to be implanted in front of the eye, without removing the natural lens.
- Trial name
- NCT06229119
- Testing
- Implantable Collamer Lens
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Myopia, Myopic Astigmatism
Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)
This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian® Implantable Collamer® Lens (ICL) in study participants who have a diagnosis of myopia or myopia with…
- Trial name
- NCT04283149
- Testing
- EVO/EVO+ Visian ICL
- Where
- 14 sites in United States
- Volunteers
- 327 people
- Sponsor
- Staar Surgical Company
Presbyopia
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The primary objective of this study is to demonstrate noninferiority in visual acuity at distance when wearing the test contact lenses (LID210464) compared to the control contact lenses (AOHG MF) after 30 days of wear.
- Trial name
- NCT05338333
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, CLEAR CARE®
- Where
- 8 sites in United States
- Volunteers
- 101 people
- Sponsor
- Alcon Research
Myopia
Pilot Evaluation of a New Galyfilcon A Contact Lens Compared to a Marketed Galyfilcon A Contact Lens
The purpose of this study is to compare lens surface characteristics and comfort between an experimental contact lens and a marketed contact lens.
- Trial name
- NCT01094730
- Testing
- galyfilcon A prototype lens, marketed galyfilcon A lens
- Where
- 9 sites in United States
- Volunteers
- 185 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Ametropia
Evaluation of the Performance of Two Contact Lenses Compared to a Marketed Lens
This study will serve to evaluate and compare the performance of two new lenses to a marketed lens.
- Trial name
- NCT01484028
- Testing
- etafilcon A control lens (1DM), etafilcon A with print and PVP for light eyes (EALE), etafilcon A with print and PVP for dark eyes (EADE)
- Where
- 15 sites in United States
- Volunteers
- 275 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.