Clinical trials: Redness
Hematocrit Change, Cardiovascular Prevention
Empagliflozin and Red Blood Cell 2,3-biphosphoglycerate Levels
The aim of this study is to investigate the hypothesis that treatment with empagliflozin may have an impact on red blood cell 2,3-biphosphoglycerate levels affecting tissue oxygen supply and thus mediating part of the cardio- and…
- Conditions
- Hematocrit Change, Cardiovascular Prevention, Empagliflozin, SGLT2-Inhibitors
- Trial name
- NCT06284850
- Testing
- Empagliflozin10Mg Tab
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Renal Failure, Chronic Kidney Disease
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
The purpose of this study was to evaluate the safety and efficacy of peginesatide in the maintenance treatment of anemia in participants on dialysis.
- Conditions
- Chronic Renal Failure, Chronic Kidney Disease, Anemia
- Trial name
- EMERALD 2 (NCT00597584)
- Testing
- peginesatide, Epoetin alfa or Epoetin beta
- Where
- 84 sites in United States, Bulgaria and 7 more
- Volunteers
- 823 people
- Sponsor
- Affymax
Immune Checkpoint Inhibitor-Induced Dermatitis, Stevens-Johnson Syndrome, Drug-Induced
SJS/TEN or Other Cutaneous Adverse Eevents Induced by Immune Checkpoint Inhibitors (ICIs) vs. Non-ICIs
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) is a severe adverse drug reaction, characterized by extensive skin detachment.
- Conditions
- Immune Checkpoint Inhibitor-Induced Dermatitis, Stevens-Johnson Syndrome, Drug-Induced, Toxic Epidermal Necrolysis Due to Drug
- Trial name
- NCT06522048
- Testing
- Observational studies do not require intervention
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chao Ji
Anemia, Surgery
Anemia and Red Blood Cells Transfusion in Oncological Surgery
Oncologic patients experience anemia and anemia is associated with poor prognosis. Transfusion is associated with adverse events, and equipoise remains on the optimal transfusion strategy in oncologic patients in surgical…
- Conditions
- Anemia, Surgery, Oncology
- Trial name
- IMPACT (NCT04101240)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Sudden Cardiac Death, Sudden Cardiac Arrest
Time and Dose Evaluation of Stearidonic Acid (SDA) to Eicosapentaenoic Acid (EPA) in Red Blood Cells
The purpose of this study is to assess the relationships between dose and time of consumption of stearidonic acid (SDA) and eicosapentaenoic acid (EPA) on EPA enrichment of red blood cell (RBC) membranes in men and women.
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Cardiovascular Disease
- Trial name
- NK (NCT01038440)
- Testing
- Safflower Oil, EPA, SDA
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Solae, LLC
Rosacea
Efficacy of IPL, an Anti-redness Dermocosmetic, and Their Combination in the Treatment of Rosacea
This study compares three approaches to treating persistent facial redness in adults with erythematotelangiectatic rosacea: intense pulsed light (IPL) treatment alone, a professional anti-redness dermocosmetic skincare regimen…
- Trial name
- NCT07729540
- Testing
- Intense Pulsed Light (IPL) - Lumecca, Rosacure anti-redness dermocosmetic regimen
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Vasovagal Syncope (VVS), Presyncope
A Warning Red Flag Classification System to Predict Risk of Vasovagal Event During Office Hysteroscopy
The goal of this pilot cross sectional study is to identify participants at risk of vasovagal reaction/syncope(VVR/VVS) during office hysteroscopy.
- Trial name
- FLAG-VS (NCT07030218)
- Testing
- Office hysteroscopy
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanvir Hospital
Ptosis, Eyelid, Conjunctiva Inflamed
The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance
The purpose of the research is to see if Upneeq ( oxymetazoline 0.1% ophthalmic solution) has an effect on eyelid position, eye redness, or patient-perceived appearance of the eyes.
- Conditions
- Ptosis, Eyelid, Conjunctiva Inflamed, Eye Manifestations
- Trial name
- NCT04831047
- Testing
- Oxymetazoline hydrochloride 0.1% ophthalmic solution
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Miami
Anemia, Blood Disease
Diamond Blackfan Anemia Registry (DBAR)
The purpose of this study is to maintain a comprehensive registry of patients with the rare inherited bone marrow failure syndrome Diamond Blackfan anemia (DBA).
- Trial name
- DBAR (NCT00106015)
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Northwell Health
Rosacea, Bilaterally Symmetric Red Skin on Cheeks
Topical Agent for Treatment of Red Skin
SR-01 may reduce facial redness. it is a topically applied product. The agent will be applied to local skin areas of subjects with red facial skin to assess affect, and then applied to the whole face to assess efficacy and safety
- Trial name
- NCT00279890
- Testing
- Topical SR-01
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Myocardial Infarction, Anemia
Cost-effectiveness and Cost-utility of Liberal vs Restrictive Red Blood Cell Transfusion Strategies in Patients With Acute Myocardial Infarction and Anaemia.
Anemia in patients with myocardial infarction (MI) is a relatively frequent issue, resulting in poorer outcome. There is equipoise regarding which transfusion strategy is best, and there is an international consensus on the…
- Conditions
- Myocardial Infarction, Anemia, Blood Transfusion
- Trial name
- REALITY (NCT02648113)
- Testing
- Restrictive transfusion, Liberal transfusion, red blood transfusion
- Where
- 2 sites in France, Spain
- Volunteers
- 668 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Prevention
Evaluation of PrEP-30: a Demonstration Project of Pre-exposure Prophylaxis for MSM and Other High-risk Group Clients at the Thai Red Cross Anonymous Clinic
PrEP-30 is a demonstration project to assess the feasibility of providing oral PrEP to MSM and other individuals at-risk for HIV in Bangkok, Thailand as a service that is funded entirely through user fees.
- Trial name
- PrEP-30 (NCT02437981)
- Testing
- PrEP
- Where
- Thailand
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Leucodepletion of Packed RBC
Impact of Lecuofiltration of Packed Red Blood Cells on Different Hematological Parameters Measured by Advia 2120
Parameters of lecuofiltration of packed Red blood cells.
- Trial name
- NCT06151977
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hyperemia
Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution in Adult and Geriatric Participants With Ocular Redness
To compare the efficacy and safety of brimonidine tartrate ophthalmic solution 0.025% with its vehicle for the treatment of ocular redness in a population of adult and geriatric participants with ocular redness.
- Trial name
- NCT01959230
- Testing
- Brimonidine Tartrate, Vehicle, Sodium Fluorescein
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Bausch & Lomb Incorporated
Ocular Redness
Study Evaluating the Safety and Efficacy of Brimonidine Tartrate Ophthalmic Solution in Adult and Geriatric Subjects
The purpose of this study is to evaluate the safety and efficacy of brimonidine tartrate 0.025% ophthalmic solution used four times daily in a population of adult and geriatric subjects
- Trial name
- NCT01675609
- Testing
- Brimonidine tartrate 0.025%
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Eye Therapies, LLC
Breast Cancer
A Data Collection Study for the Evaluation of a Novel Infra-red Breast Imaging System for Risk Assessment
Three-dimensional functional Metabolic Imaging (3D MIRA) is a new infrared imaging technology using the Real Imager 8 (RI8) developed by Real Imaging.
- Trial name
- NCT02505698
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Real Imaging Ltd.
Keloid
Ethosomal Gel Bearing Losartan 5% for Keloid Treatment
The objectives are to compare the efficacy of pre and post-treatment and between 5% losartan potassium loaded in ethosomal gel and 10 mg/ml triamcinolone acetonide injection based on the indicator score of The patient and…
- Trial name
- NCT05893108
- Testing
- Ethosomal gel bearing losartan 5%, triamcinolone acetonide 10 mg/ml
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Yuni Eka Anggraini
Hidradenitis Suppurativa
A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
The purpose of this study is to learn about the safety and effects of the study medicine (called Ritlecitinib) for the possible treatment of hidradenitis suppurativa (HS).
- Trial name
- NCT07228390
- Testing
- Ritlecitinib
- Where
- 60 sites in United States, Canada and 4 more
- Volunteers
- 128 people
- Sponsor
- Pfizer
Sickle Cell Disease
Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia:
Despite important advances in the current understanding of sickle cell vaso-occlusion, the basis of its control and prevention remain partially unknown.
- Trial name
- STRESS (NCT03368924)
- Testing
- SCA patients (SS genotype)
- Where
- Guadeloupe
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Whole Blood Donation and Leukoreduction
Clinical Investigation to Evaluate the Hemanext® Oxygen Reduction System - Pivotal Trial
The primary goal of Hemanext. is to improve red cell storage through novel storage methods. Based on our review of the pertinent literature, there is substantial evidence suggesting that prolonged exposure to oxygen during…
- Trial name
- NCT03301779
- Testing
- Hemanext Red Blood Cell Processing System
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hemanext
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