Clinical trials: Rebound Pain
Acute Pain, Orthopaedic Surgery
Effect of Liposomal Bupivacaine on Rebound Pain After Peripheral Nerve Block in Orthopedic Surgery.
This study will prospectively compare the preventive effect of liposomal bupivacaine combined with plain bupivacaine versus plain bupivacaine alone on rebound pain after nerve block in patients undergoing orthopedic extremity…
- Trial name
- NCT07606911
- Testing
- liposomal bupivacaine, Normal Saline
- Where
- China
- Volunteers
- 668 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Pain, Postoperative Care
Prevention of Rebound Pain After Axillary Block
This will be a single-center randomized double blind placebo control clinical trial. In the cohort of patients undergoing hand surgery under axillary nerve block, participants are recruited from those who are willing to consent…
- Trial name
- NCT07313553
- Testing
- Saline, Dexamathsone 4mg/ml associated with experimental arm
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Rebound Pain, Arthroscopic Knee Surgery
Effect of Oliceridine on Rebound Pain
The purpose of this clinical study was to identify the risk factors for postoperative pain outburst in patients undergoing arthroscopic knee surgery after Oliceridine and nerve block, and to evaluate the effect of oxeridine on…
- Conditions
- Rebound Pain, Arthroscopic Knee Surgery, Oliceridine
- Trial name
- NCT06382896
- Testing
- No intervention
- Where
- China
- Volunteers
- 320 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Gastroesophageal Reflux
Study on Hydrotalcite for Relief of Acid Symptoms Due to Acid Rebound After Stopping Long-Term PPI Therapy
This observational study aims to explore the effectiveness of hydrotalcite, marketed as Talcid, in alleviating acid-related symptoms that occur due to an acid rebound after discontinuing a non-/no-longer-indicated long-term…
- Trial name
- NCT07291700
- Testing
- Hydrotalcite (Talcid, BAYX002833)
- Where
- 2 sites in Germany
- Volunteers
- 167 people
- Sponsor
- Bayer
Orthopedic Procedures, Pain, Postoperative
Risk Model for Severe Rebound Pain After Lower Limb Orthopedic Surgery Involving Single-Shot Sciatic Nerve Blocks
Rebound pain is a well-recognized phenomenon after the effects of a nerve block wear off. Severe rebound pain can happen after outpatient surgery, with patients often needing to come back to the hospital or use other health care…
- Conditions
- Orthopedic Procedures, Pain, Postoperative, Surgery, Nerve Block
- Trial name
- NCT05018104
- Testing
- This is not an interventional study
- Where
- Canada
- Volunteers
- 1,270 people
- Sponsor
- University of British Columbia
Postoperative Pain
Peripheral Nerve Block Anaesthesia for Ankle Fracture Surgery - an Exploratory Study: Is Rebound Pain a Problem?
The purpose of this exploratory study is to characterize the postoperative pain profile of patients undergoing operation with internal fixation of an ankle fracture under nerve block anaesthesia.
- Trial name
- NCT02100098
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Herlev Hospital
Adjuvants, Anesthesia, Brachial Plexus Anesthesia
Variation in the Effect of Dexamethasone Associated With Axillary Plexus on the Occurrence of Rebound Pain
The study will evaluate pain and recovery after a single injection axillary plexus block combined with an intravenous dose of 0.1 mg/kg dexamethasone in ambulatory patients undergoing upper extremity bone surgery.
- Trial name
- VEDR (NCT05763433)
- Testing
- upper extremity bone surgery
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Postoperative Pain, Postoperative Complications
Rebound Pain and Related Factors in Postoperative Patients With Total Knee Arthroplasty
The aim of this prospective observational study is to detect rebound pain and related factors in postoperative patients with total knee arthroplasty.
- Conditions
- Postoperative Pain, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT05910281
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Gulhane Training and Research Hospital
Migraine
Oral Dexamethasone for Treatment of Migraine
The aim of this project is to determine if a single dose of oral dexamethasone at the time of discharge from the emergency department (ED) [after successful treatment] prevents rebound headache.
- Trial name
- NCT00216736
- Testing
- Dexamethasone
- Where
- Australia
- Volunteers
- 63 people
- Sponsor
- The Joseph Epstein Centre for Emergency Medicine Research
Total Knee Arthroplasty, Sedation
The Effect of Sedation on Rebound Pain in Knee Arthroplasty
Dexmedetomidine is often used for sedation procedures. It has also been shown to have a pain-protective effect. Researchers predicted that using dexmedetomidine for sedation in total knee arthroplasties performed under spinal…
- Trial name
- NCT06555458
- Testing
- Dexmedetomidine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Diabetes
Effect of Different Exercises on Musculoskeletal Pain,Glucose Level and Quality of Life Among Patients With Diabetes
Background. Diabetes is a global epidemic disease. The prevalence of diabetes for all age groups worldwide was estimated to be 2.8% in 2000 and is predicted to affect 4.4% by 2030.
- Trial name
- NCT03200795
- Testing
- Rebound exercise, Circuit training exercise
- Where
- Nigeria
- Volunteers
- 90 people
- Sponsor
- University of KwaZulu
Radius Fracture Distal, Rebound Pain
Ropivacaine Concentration and Rebound Pain
The goal of this clinical trial is to see if the concentration of a local anesthetic (ropivacaine) in peripheral nerve block is related to the severness of pain after surgery of distal radius fractures in adults.
- Trial name
- NCT06950372
- Testing
- Ropivacaine concentration low, Ropivacaine concentration high
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Postoperative Pain, Arthroscopic Shoulder Surgery
Intravenous Dexamethasone Added to Dexmedetomidine After Superior Trunk Block
This prospective, randomized, placebo-controlled, triple-blind trial will evaluate the effect of adding intravenous dexamethasone to intravenous dexmedetomidine on postoperative analgesia after superior trunk block in adult…
- Conditions
- Postoperative Pain, Arthroscopic Shoulder Surgery, Regional Anesthesia
- Trial name
- STB-DEX (NCT07795281)
- Testing
- Intravenous Dexamethasone, Intravenous Dexmedetomidine, Superior Trunk Block
- Volunteers
- 70 people
- Sponsor
- Gaziantep City Hospital
Rebound Pain, Liposomal Bupivacaine
Comparison of Liposomal Bupivacaine Versus Ropivacaine in Alleviating Rebound Pain
Shoulder arthroscopy is a frequently performed orthopedic procedure used to address various issues like rotator cuff tears, instability, and stiffness.
- Trial name
- NCT07196631
- Testing
- Liposomal Bupivicaine, ropivacaine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Liu Jiuhong
Rebound Pain, Sciatic Nerve Block
Influence of Sensory Block Duration on Rebound Pain After Outpatient Foot Surgery Under Popliteal Sciatic Nerve Block.
Rebound pain after surgeries under peripheral nerve block is defined as the appearance of severe acute postoperative pain after regression of the sensory block.
- Conditions
- Rebound Pain, Sciatic Nerve Block, Foot Surgery, Outpatient Surgery
- Trial name
- NCT06309381
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Hospital Universitario Doctor Peset
Rebound Pain, Shoulder Arthroplasty
Effect of Local Anesthetic Concentration on Rebound Pain
Randomized control study that compares different concentrations of local anesthetic to investigate whether a lower concentration of local anesthetic would contribute to lower rebound pain scores at 24 hours post op in patients…
- Conditions
- Rebound Pain, Shoulder Arthroplasty, Interscalene Block
- Trial name
- RPRCT (NCT07146685)
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Postoperative Sensitivity, Rebound Pain
Menstrual Cycle Effects on Postoperative Sensitivity and Rebound Pain in Composite Restorations
This study aims to evaluate how different phases of the menstrual cycle affect pain after dental treatments. Specifically, it investigates two types of pain: Postoperative sensitivity (pain felt after the filling procedure), and…
- Conditions
- Postoperative Sensitivity, Rebound Pain, Menstrual Cycle, Composite Restorations
- Trial name
- NCT06886243
- Testing
- Direct Posterior Composite Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Firat University
Inguinal Hernia
The Effect of Dexamethasone on Rebound Pain in Patients Receiving Ilioinguinal and Iliohypogastric Nerve Block
Rebound pain is a newly defined phenomenon, observed within the first 24 hours after the operation. Open inguinal hernia repair is a common surgical procedure that can be associated with pain of the either acute or chronic…
- Trial name
- NCT05172908
- Testing
- Dexamethasone, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karaman Training and Research Hospital
Post Operative Analgesia, Rebound Pain
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A
Rebound pain after peripheral nerve blocks reduces the benefits of regional anesthesia and increases opioid consumption. This rebound pain most likely results from suboptimal pain management, as patients receiving a peripheral…
- Conditions
- Post Operative Analgesia, Rebound Pain, Post Operative Pain, Acute
- Trial name
- REBOUND (NCT07666971)
- Testing
- Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois