Clinical trials: Rapid Detection
Malaria
Evaluating the Clinical Performance and Usability of Novel Malaria RDTs in Brazil
Prospective cross-sectional diagnostic accuracy study with 1,000 patient participants and 30 lay provider/health care worker participants. The patient participant population will be recruited at clinics.
- Trial name
- NCT05317117
- Testing
- NxTek™ Malaria P.f plus Rapid Diagnostic Test (RDT) and NxTek™ Malaria P.f/P.v RDT
- Where
- Brazil
- Volunteers
- 1,030 people, healthy volunteers welcome
- Sponsor
- PATH
Covid-19
Rapid Diagnostic Test for COVID-19 Based on Antibody Detection (YCOVID)
Ycovid-19 aims to be a rapid diagnostic test for SARS-CoV-2 infection, which will allow a reliable diagnosis to be made in 10 minutes, and on easy-to-use devices.
- Trial name
- YCOVID (NCT04490837)
- Testing
- ELISA and Rapid test to detect antibodies against COVID-19
- Where
- Spain
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Tuberculosis
Rapid Detection of Rifampin and Isoniazid Resistance by PCR Before Tuberculosis (TB) Treatment Initiation
French guidelines currently recommend to initiate a 4-drug containing regimen associating isoniazid (INH or H), rifampicin (RIFor RMP or R), pyrazinamide (PZA or Z) and ethambutol (EMB or E) pending the results of drug…
- Trial name
- FAST-TB (NCT02231229)
- Testing
- PCR-based strategy, conventional therapy
- Where
- 2 sites in France
- Volunteers
- 204 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Periodontitis, Gingivitis
Diagnostic Accuracy of Rapid Non-clinical Screening Tests for Early Detection of Periodontitis
Gum disease is the 6th most prevalent disease of mankind. It is a non-communicable non-resolving inflammation; if untreated it leads to tooth loss and inability to chew properly.
- Trial name
- NCT03928080
- Testing
- Bleeding on brushing
- Where
- China
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Tuberculosis
Development of Molecular Diagnostic Platform for Tuberculosis
This study evaluates new technique for diagnosis of tuberculosis. Among patients who are suspected with tuberculosis, participants will be tested conventional method including Xpert TB/RIF assay, and new diagnostic technique…
- Trial name
- NCT04734236
- Testing
- New technique vs Xpert
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus
Volatile Organic Compounds in Staphylococcus Aureus Patients
The zNose® MRSA test is a non-invasive breath test for markers of Staphylococcus aureus, which may predict the probability of bacterial organisms in the anterior nares, throat and respiratory tract, wounds, and anus and therefore…
- Conditions
- Staphylococcus Aureus, Methicillin-resistant Staphylococcus Aureus, Nosocomial Disease
- Trial name
- MRSAVOC (NCT01379053)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
Alzheimer's Disease Diagnosis
Clinical Evaluation of Blood-Based Assays for Rapid Detection of Aβ Pathology in Alzheimer's Disease
Background: Blood-based biomarkers show promise in predicting Alzheimer's disease (AD) pathology and progression; however, inconsistencies in detection standards hinder clinical application.
- Trial name
- CLEAR AD (NCT06889896)
- Testing
- After Blood samples collection, these samples are analyzed at a central laboratory under blinded conditions using multiple detection methods to measure plasma levels of Aβ40, Aβ42, t-tau, and p-tau
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Infertility, Female
Rapid Detection Method for Microorganisms in the Lower Genital Tract
Mycoplasma, chlamydia, and gonococcal infection of the female lower genital tract can lead to infertility and various adverse pregnancy outcomes.
- Trial name
- NCT05678751
- Testing
- lower genital tract microorganisms detection using Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Shenzhen Second People's Hospital
Cerebral Palsy, Pediatric Neurological Disorder
Lung Ultrasound for Infants' Swallowing Disorders
The aim is to test the effectiveness of lung ultrasound (LUS) in the dynamic assessment of aspiration related to abnormal swallowing in infants and young children with neurological impairment (cerebral palsy/developmental…
- Conditions
- Cerebral Palsy, Pediatric Neurological Disorder, Developmental Disability
- Trial name
- LUNCH (NCT04253951)
- Testing
- Lung Ultrasound (LUS)-monitored feeding trial
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Fondazione Stella Maris
Lung Cancer
Rapid Absorbance-based Detection of Inner Cheek Cell Abnormalities Using Light Spectroscopy for Risk Evaluation of Lung Cancer to Enable Critical Decision Support in Targeted Patient Populations
Overview Sierra Medical is at the forefront of early detection of lung cancer by creating AIR-DS, a non-invasive early detection test.
- Trial name
- RADICAL-REACT (NCT07051044)
- Testing
- AIR-DS
- Where
- 2 sites in United Kingdom
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sierra Medical Ltd.
Group B Streptococcus
Group B Streptococcus (GBS) Polymerase Chain Reaction (PCR) Concordance Study
The investigators are comparing three different methods of testing for an infection which is commonly found in women. The infection is caused by a bacterium called Group B Streptococcus.
- Trial name
- NCT00972894
- Where
- 2 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- HCA International Limited
SARS-CoV-2, Covid-19
Performance Evaluation of SARS-COV-2 (Covid-19) Antigen Rapid Test
The SARS-CoV-2 Antigen Rapid Test is a bioassay intended for rapid point-of-care detection of the SARS-CoV-2 virus. Performance of the SARS-CoV-2 Antigen Rapid Test assay will be assessed by comparison to a reference method.
- Conditions
- SARS-CoV-2, Covid-19, Coronavirus
- Trial name
- NCT04808921
- Testing
- Xiamen Wiz Biotech Co., Ltd. SARS-CoV-2 Antigen Rapid Test
- Where
- United States
- Sponsor
- Sky Medical Supplies & Equipments, LLC
COVID-19, Sars-CoV-2 Infection
This Trial is a Clinical Performance Validation Study That Will Evaluate the Clinical Agreement of the Sky Medical™ Rapid Antigen Test Comparing the Antigen Rapid Test to RT-PCR
Prospective study that will evaluate the clinical agreement of the Sky Medical™ Rapid Antigen Test compared to SARS-CoV-2 RT-PCR.
- Trial name
- NCT05491993
- Testing
- Sky Medical™ Rapid Antigen Test
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Sky Medical Supplies & Equipments, LLC
Celiac Disease in Children
Validation of a New Innovative Method for Specific Marker Detection in Celiac Disease
Celiac disease (CD) is a common auto-immune disorder induced by gluten ingestion in genetically susceptible individuals (HLA-DQ2/DQ8).
- Trial name
- NCT06324539
- Testing
- Diagnostic Test: Rapid Intestinal anti-TG2 Assay
- Where
- 4 sites in Italy
- Volunteers
- 332 people
- Sponsor
- IRCCS Burlo Garofolo
Covid19
Diagnostic Validation of Rapid Detection of the COVID-19 Causative Virus (SARS-CoV-2) in Saliva Samples by Mass Spectrometry
In order to control the COVID-19 pandemic, a policy for the diagnosis and screening of people likely to be infected with SARS-CoV-2 has been established The reference diagnostic test is RT-PCR on nasopharyngeal swab.
- Trial name
- SALICOV (NCT04712175)
- Testing
- Nasopharyngeal sampling, Saliva sampling
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Plasmodium Falciparum
ELISA Validation of Hypersensitive Rapid Diagnostic Test Results for Detection of P. Falciparum
Elimination of P. falciparum (PF) malaria across a territory requires universal access to treatment of clinical cases for communities, and specific targeting of places or population groups where malaria transmission persists in…
- Trial name
- ELISA (NCT03132402)
- Testing
- ELISA validation
- Where
- Thailand
- Volunteers
- 1,656 people
- Sponsor
- University of Oxford
Diarrhea Bloody
Improvements Through the Use of a Rapid Multiplex PCR Enteric Pathogen Detection Kit in Children With Hematochezia
Children presenting for emergency department (ED) care with bloody diarrhea (i.e. hematochezia) represent a diagnostic challenge.
- Trial name
- NCT03362970
- Testing
- BioFire Gastrointestinal Panel FilmArray®, Standard of Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Pharyngitis
Comparison of Two Rapid Antigen Detection Tests for the Detection of Group-A Streptococcal Pharyngitis in Children
Group A streptococcal (GAS) pharyngitis in children represents a frequent diagnostic challenge in pediatric emergency departments, since isolated signs and clinical prediction rules are insufficient to accurately discriminate…
- Trial name
- NCT03099018
- Testing
- Sofia Strep A FIA
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Geneva
Mild Cognitive Impairment (MCI), Dementia
Telemedicine Self-examination of Speech and Memory for Rapid Detection of Cognitive Impairments Using Machine Learning Methods
Early cognitive disorders diagnosis is becoming increasingly important due to population aging. The most common causes include Alzheimer's disease and frontotemporal dementia.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Mild Cognitive Impairment (MCI) Amnestic, Frontotemporal Degeneration (FTD)
- Trial name
- NCT07558785
- Testing
- The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), the Mississippi Aphasia Screening Test, Amnesia Light and Brief Assessment (ALBA)
- Where
- 3 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Pregnancy
Accuracy of Whole-Blood Testing for Rapid Detection of Pregnancy
It is common practice in the emergency medicine department to rapidly assess pregnancy status through the use of either urine or serum in pregnancy tests.
- Trial name
- NCT00373139
- Where
- United States
- Volunteers
- 633 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos