Clinical trials: Radiostereometric Analysis
Osteoarthritis, Osteonecrosis
E-Type - Early Wear of Polyethylene Liners Used in DMC
This is a single-centre, randomized, double-blinded controlled non-inferiority trial that will be conducted at the Orthopaedic Department at Uppsala University Hospital, Uppsala.
- Conditions
- Osteoarthritis, Osteonecrosis, Dysplasia; Hip
- Trial name
- E-type (NCT07863557)
- Testing
- Total Hip Arthroplasty
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University
THA
Five-year Migration Pattern and Bone Mineral Density for the Tri-Lock and Summit Femoral Stems.
The incidence of primary hip joint prosthesis is 180 per. 100,000 inhabitants. In male patients younger than 50 years the 10-years survival of the prosthesis is 89 % and 82 % over 15 years.
- Trial name
- NCT06019026
- Testing
- Tri-Lock, Summit
- Volunteers
- 52 people
- Sponsor
- Regional Hospital Holstebro
Hip Osteoarthritis
Prospective Catalystem CT-RSA
Multi-Centre Study in patients undergoing Total Hip Arthroplasty with the Smith+Nephew CATALYSTEM™ Primary Hip System. The primary objective is to establish the mean inferior stem migration (subsidence) of the CATALYSTEM™ stem…
- Trial name
- NCT07698717
- Testing
- CATALYSTEM
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Osteoarthritis
Radiostereometric Analysis (RSA) and DEXA to Evaluate Fixation and Wear of the Restoration ADM Acetabular System
The dual mobility design concept for acetabular liners, as is used in the Restoration ADM Acetabular System, has been applied in various implants since its introduction by Gilles Bousquet in France in 1976.
- Trial name
- NCT01273324
- Testing
- ADM Cup
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Dalhousie University
Osteoarthritis, Hip, Arthropathy of Hip
Evaluation of Cemented and Cementless Fixation of Dual-mobility Hip Prosthesis in Elderly Patients With Osteoarthritis
The aim of this project is to investigate prosthesis fixation in the bone, respectively cemented and uncemented operation method of Avantage® dual-mobility acetabular cup in elderly patients, wear of the plastic in dual-mobility…
- Trial name
- NCT02404727
- Testing
- cup fixation, Avantage® Cup
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoarthritis, Knee
Cemented Versus Cementless Unicompartmental Knee Arthroplasty
Unicompartmental knee replacement for selected cases of osteoarthritis is less invasive than total knee replacement. It gives better range of movement; patients stay for shorter time in the hospital and have a more natural feel…
- Trial name
- NCT05935878
- Testing
- Cementless Oxford Unicompartmental Knee Arthroplasty, Cemented Oxford Unicompartmental Knee Arthroplasty
- Volunteers
- 47 people
- Sponsor
- Oxford University Hospitals NHS Trust
Total Knee Replacement, Total Knee Replacement Surgery
Mako Cementless TKA vs Mako Cemented TKA
The overall aims of this prospective, randomised, single-blinded controlled trial are to compare functional, radiological and clinical outcomes in Mako robotic-arm assisted cementless Total Knee Arthroplasty (TKA) versus Mako…
- Conditions
- Total Knee Replacement, Total Knee Replacement Surgery, Total Knee Arthroplasty, Osteoarthritis (OA) of the Knee
- Trial name
- NCT06929871
- Testing
- Mako cementless TKA, Mako cemented TKA
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University College, London
Total Hip Arthroplasty
Corail Stability at 5-Years Post-Total Hip Arthroplasty
Total hip arthroplasty (THA) is the mainstay, definitive management for end-stage hip osteoarthritis. Despite improvements of surgical and patient factors, prosthesis-related complications continue to increase in number.
- Trial name
- NCT05893563
- Testing
- Standard Post-Operative Clinic Visit, Study-Specific Outcomes
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis, Hip
Prospective Evaluation of Fixation of the Prime Acetabular Cup
This is a prospective study to compare migration of the Microport Prime acetabular cup to a well-established acetabular cup design after total hip replacement.
- Trial name
- NCT04039984
- Testing
- Prime Cup
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Taperloc Versus Taplerloc Microplasty
This evaluation is conducted to evaluate the safety and performance of two different stem lengths of the Taperloc Total Hip System.
- Trial name
- NCT00757107
- Testing
- Taperloc Microplasty, Taperloc standard
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Ingemar Ivarsson
Pes Planovalgus
New Bone Grafting Technique in Paediatric Foot Surgery. Validation of Outcome Measures
The purpose of this study is to determine whether structural calcium ceramic bone graft substitute (ReproBone™) is non-inferior compared to autologous tricortical iliac crest bone graft in lateral calcaneal lengthening…
- Trial name
- NCT01770574
- Testing
- ReproBone, calcaneal lengthening
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Aarhus
Osteoarthritis, Knee
RSA Study of Persona TKA With CR vs MC Polyethylene
The aim of this study is to evaluate, over a 2 year period, the migration pattern, function and the possibility of anatomical reconstruction of a relatively new total knee arthroplasty (TKA) concept, the Persona.
- Trial name
- NCT03494348
- Testing
- Medial Congruent Polyethylene (MC)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Hip Osteoarthritis
Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis
This is a randomized, double-blind and placebo-controlled study to evaluate the efficacy of zoledronic acid on the biologic incorporation of cementless hip prosthesis in postmenopausal female patients.The study population…
- Trial name
- NCT01218035
- Testing
- zoledronic acid
- Where
- Finland
- Volunteers
- 49 people
- Sponsor
- Turku University Hospital
Hip Fractures, Femoral Neck Fractures
Undisplaced Femoral Neck Fractures 2 Hansson Pins or 3 Pins Interlocked in Plate (Pinloc) Using RSA
Femoral neck fractures represent about half of the hip fractures and are further divided into displaced and undisplaced fractures. Displaced femoral neck fractures are almost always treated surgically with arthroplasty.
- Trial name
- NCT02699619
- Testing
- Pinloc, 2 Hansson pins
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- Oslo University Hospital
Osteoarthritis, Hip
Mini Stem Radiostereometric Analysis Study
The objectives of this study are to assess migration of the MIS Stem compared to the Synergy Hip System using Radiostereometric Analysis (RSA), and to assess the long-term safety and effectiveness of the study device.
- Trial name
- MISRSA (NCT01064531)
- Testing
- MIS Femoral Neck Stem implant
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Smith & Nephew, Inc.
Knee Arthroplasty, Total, Knee Osteoarthritis
Cementless Triathlon 5YR Follow-Up
All artificial joint implants need to be solidly held (fixed) within the bone. Cementless fixation has become a popular method to achieve fixation for total knee replacements where the bone grows directly onto the implanted…
- Conditions
- Knee Arthroplasty, Total, Knee Osteoarthritis, Radiostereometric Analysis
- Trial name
- NCT05877261
- Testing
- Cementless Total Knee Replacement
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Femoral Neck Fractures, Internal Fixation; Complications
Evaluation of Fracture Migration After Internal Fixation of Femoral Neck Fractures in Younger Adults: A Clinical RCT Using RSA
The goal of the clinical trial is to compare different surgical methods for internal fixation of femoral neck fractures in younger adults.
- Conditions
- Femoral Neck Fractures, Internal Fixation; Complications, Hip Fractures
- Trial name
- NCT06521671
- Testing
- Dynaloc implant, Cannulated cancellous screws, Sliding hip screw
- Where
- 4 sites in Denmark
- Volunteers
- 75 people
- Sponsor
- Odense University Hospital
Hip Osteoarthritis
Denosumab in Enhancement of Bone Bonding of Hip Prosthesis in Postmenopausal Women
This randomized clinical trial will evaluate the efficacy of an antiresorptive osteoporosis drug (denosumab) in prevention of periprosthetic bone loss and in promotion of implant osseointegration (bone bonding) in postmenopausal…
- Trial name
- ProliaHip (NCT01926158)
- Testing
- Denosumb
- Where
- Finland
- Volunteers
- 65 people
- Sponsor
- Turku University Hospital
Revision Total Knee Replacement
Pilot Study Using Radiostereometric Analysis (RSA) to Evaluate the Fixation of the Tibial Components in the DePuy M.B.T. Revision Knee System
Motivated by the growing number of revision total knee arthroplasty (TKAs) and the interest among surgeons to quantify the effectiveness of specific implant designs, the goal of the current project is to use Radiostereometric…
- Trial name
- NCT01647386
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Michael Dunbar
Knee Osteoarthritis
Trial Comparing Alignment Techniques - RSA of ATTUNE Knee System
The purpose of this study is to compare migration patterns between mechanical and anatomic alignment surgical techniques for the Attune S+ CR-FB knee system using model-based RSA over the first 2 post-operative years.
- Trial name
- NCT04079751
- Testing
- Neutral Mechanical Alignment, Anatomical Alignment
- Where
- 2 sites in Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network