Clinical trials: Radiostereometric Analysis
Spinal Fusion, Lumbar Discectomy
Use of Radiostereometric Analysis Beads (RSA) to Measure Motion in the Spine, Following Lumbar Spinal Surgery
Radiostereometric Analysis (RSA) is a new imaging technique used to measure motions in the spine. It provides more accurate measurements that could help in diagnosing problems in the spine earlier than standard xray techniques.
- Trial name
- NCT00152152
- Testing
- Radiostereometric Analysis beads inserted during surgery
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- State University of New York - Upstate Medical University
Femoral Neck Fractures, Bone Density
Radiostereometric Analysis of Acetabular Wear and Periprosthetic Bone Mineral Density Changes in Hemiarthroplasties
Substudy and continuation of HEMI-SAB-UUS (NCT00491673) Study on radiostereometric measurements of acetabular wear in bipolar hemiarthroplasties and measurements of periprosthetic bone mineral density in cemented and uncemented…
- Conditions
- Femoral Neck Fractures, Bone Density, Acetabular Wear, Hemiarthroplasty
- Trial name
- HEMI-RSADEXA (NCT00607516)
- Testing
- Cemented primary bipolar hemiarthroplasty of the hip, Uncemented primary bipolar hemiarthroplasty of the hip
- Where
- Norway
- Volunteers
- 22 people
- Sponsor
- Ullevaal University Hospital
Arthritis of the Hip
Polarstem Versus Corail; a Comparison of Micromotion and Periprosthetic Bone Remodelling of Two Femoral Stems
A randomised controlled trial comparing a recently introduced femoral stem with an established stem for total hip arthroplasty (THA). 60 patients will be randomised into one of the two groups 1.
- Trial name
- NCT05815953
- Testing
- Polarstem, Corail
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Helse-Bergen HF
Total Knee Arthroplasty, Knee Osteoarthritis
NitrX Total Knee Arthroplasty RSA
Metal hypersensitivity is a recognized complication in some patients following total joint arthroplasty. This can result in a reaction to metal particles from the implants placed in the joint and cause tissue injury.
- Conditions
- Total Knee Arthroplasty, Knee Osteoarthritis, Radiostereometric Analysis
- Trial name
- NCT05151315
- Testing
- Total Knee Arthroplasty with Evolution® NitrX™ Knee System, Total Knee Arthroplasty with Evolution Knee System
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Hip Arthroplasty
Importance of Hollow or Solid Centralizer for Polished, Collarless and Tapered Stems in Total Hip Arthroplasty
The study aims at comparing the effect of hollow or solid centralizer designs on the long time fixation behaviour of hip prosthesis stems that are polished, tapered and collarless.
- Trial name
- NCT01918540
- Testing
- Hollow Centralizer, Solid Centralizer, MS-30 femoral stem
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Osteoarthritis
Simplex High Viscosity Bone Cement in Primary Total Knee Arthroplasty
In this study the investigators propose to monitor subjects who have received Triathlon total knee components inserted with HV cement.
- Trial name
- NCT02572310
- Testing
- Simplex High Viscosity Bone Cement
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Michael Dunbar
Distal Femur Fractures
Radiostereometric Analysis of Fracture Healing in Distal Femur Fractures
The investigators are doing this research study to look at how distal femoral fractures (knee bone break) heal. In this study, the investigators will use Radiostereometric Analysis (RSA) to look at how the pieces of femur bone…
- Trial name
- RSA (NCT01593176)
- Testing
- Placement of RSA beads
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Degenerative Arthritis
PINNACLE® DM RSA Study
The primary objective is to establish the mean superior cup migration of the PINNACLE® Dual Mobility Construct using model-based RSA over the first two years post-implantation.
- Conditions
- Osteoarthritis, Degenerative Arthritis, Revision Arthroplasty
- Trial name
- PIN DM (NCT05357664)
- Testing
- Total Hip Arthroplasty, Revision Total Hip Arthroplasty
- Where
- 3 sites in Canada
- Volunteers
- 11 people
- Sponsor
- DePuy Orthopaedics
Surgery, Surgical Incision
Direct Superior Approach (DSA) vs Posterior Approach (PA) in THA
Total Hip Arthroplasty (THA) is a highly effective treatment for patients with symptomatic hip osteoarthritis. The surgical approach in THA is important as it influences postoperative clinical recovery, functional outcomes, and…
- Conditions
- Surgery, Surgical Incision, Patient Satisfaction
- Trial name
- NCT04191993
- Testing
- Total hip arthroplasty
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University College, London
Personal Satisfaction, Genu Varum
RSA and Clinical Comparison of Anatomical and Mechanical Alignment in Total Knee Replacement
Current practice in orthopedics is to recommend TKA implantation with the femoral and tibial components perpendicular to their mechanical axis.
- Trial name
- NCT02256904
- Testing
- Anatomical TKA, Mechanical TKA
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Osteoarthritis
Effect of Cutting Blades for Total Knee Arthroplasty on Implant Migration
There have been considerable efforts to control rising health care costs. One of the more recent developments is the practice of reprocessing single use medical devices.
- Trial name
- NCT01772589
- Testing
- New saw blade, Reprocessed saw blade
- Where
- Canada
- Sponsor
- Glen Richardson
Arthritis
SmartSet HV and Palacos R RSA Bone Cements in Primary Total Hip Arthroplasty
A randomised radiostereometric study comparing SmartSet HV and Palacos R acrylic bone cements.
- Trial name
- NCT00837850
- Testing
- Bone cement 1, Bone cement 2
- Volunteers
- 35 people
- Sponsor
- Norwegian University of Science and Technology
Hip Osteoarthritis
Comparison of Two Hydroxy-apatite Coated Hip Stems
In this study, the investigators propose to randomize 80 subjects to receive either the Avenir cementless hip stem or a competing, HA-coated hip stem (Corail, DePuy-Synthes) and follow these patients for a period of 2 years…
- Trial name
- NCT03577522
- Testing
- Avenir cementless hip stem, Corail HA-coated hip stem
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Osteoarthritis Arthritis, Joint Diseases
Persona Versus NexGen
The NexGen TKR (Zimmer, Warsaw, Indiana, USA) is a proven TKR design that has reported excellent medium and long-term results in clinical studies and in implant registries all around the world.
- Conditions
- Osteoarthritis Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
- Trial name
- NCT02269254
- Testing
- Persona PS Knee Prosthesis by Zimmer, NexGen PS Knee Prosthesis by Zimmer
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Leiden University Medical Center
Arthritis of the Hip
Cemented Marathon/Corail Versus Pinnacle/Corail
A randomised, comparative, prospective, single-blinded trial of two hip prosthesis: 1. Marathon cemented all-poly acetabular cup(Depuy, Warsaw, Indiana), Corail uncemented femoral stem(Depuy, Warsaw, Indiana), 32mm Alumina Biolox…
- Trial name
- NCT01693627
- Testing
- Pinnacle/Corail with collar, Marathon/Corail with collar, Pinnacle/Corail without collar
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Haukeland University Hospital
Osteoarthritis, Knee
All-Polyethylene Tibias in TKA: PS vs CS Implants
This is a randomized control trial where patients will be randomized to receive one of two types of total knee arthroplasty (TKA) all-polyethylene (AP) tibial components: cruciate retaining (CR) or posterior stabilized (PS).
- Trial name
- NCT03569670
- Testing
- Posterior stabilized all-polyethylene tibial component, Cruciate retaining all-polyethylene tibial component
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Hip Arthroplasty
Migration and Head Penetration of Vitamin-E Diffused Cemented Polyethylene Cup in Total Hip Arthroplasty
In vitro, Vitamin-E diffused, highly cross-linked polyethylene (PE) have been shown to have superior wear resistance and improved mechanical properties as compared to that of standard highly cross-linked PE.
- Trial name
- E1-hip (NCT02254980)
- Testing
- Vitamin-E diffused polyethylene acetabular component, Standard polyethylene acetabular component
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Danderyd Hospital
Osteoarthritis
Importance of Restoring Biomechanical Correct Hip Anatomy During Total Hip Arthroplasty
The purpose of this prospective, randomized study is to evaluate the importance of restoring the exact individual hip biomechanics during total hip arthroplasty.
- Trial name
- NCT01512550
- Testing
- GF hip guide, Stryker Navigation System, ABG II modular femoral component
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Region Skane
Gonarthrosis; Primary, Degenerative Joint Disease of Knee
The Effect of Three Prosthesis Designs in Total Knee Arthroplasty
The purpose of this study is to compare three prosthesis designs to compare three prosthesis designs for total knee arthroplasty and determine the best option for patients in need of a knee replacement.
- Trial name
- NCT03059927
- Testing
- Knee arthroplasty, Cruciate retaining, Knee arthroplasty, Anterior stabilized, Knee arthroplasty, Posterior stabilized
- Where
- 2 sites in Norway
- Volunteers
- 216 people
- Sponsor
- Lovisenberg Diakonale Hospital
Knee Osteoarthritis, Knee Arthropathy
Radiostereometry in Knee Arthroplasty
The innovative aspect of this research is the possibility of combining the data collected with radiostereometric model based Radiostereometry with the data collected through the Galeazzi Institute Registry.This opens the prospect…
- Conditions
- Knee Osteoarthritis, Knee Arthropathy, Aseptic Loosening
- Trial name
- NCT04960111
- Testing
- RSA
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio