Clinical trials: Radicular Pain
Back Pain Without Radiation, Low Back Pain
A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain.
Purpose: This is a randomized clinical trial comparing the effects of three different medications for acute low back pain (LBP):Ketorolac, Ibuprofen, Diclofenac Hypothesis: A daily regimen of ketorolac will provide greater relief…
- Trial name
- NCT03861611
- Testing
- Ketorolac, Ibuprofen, Diclofenac
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Montefiore Medical Center
Lumbar Disc Herniation, Annular Disc Tear
A Post Marketing Surveillance Study
This study is a prospective, multi-center study to monitor the early safety and performance of one iteration of the Barricaid Anular Closure Device (ACD) - 6mm anchor width, when used as an adjunct to limited discectomy.
- Conditions
- Lumbar Disc Herniation, Annular Disc Tear, Annular Tear of Lumbar Disc
- Trial name
- 6MM (NCT03366779)
- Testing
- 6mm annular closure device
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 20 people
- Sponsor
- Intrinsic Therapeutics
Sciatica, Lumbosacral Radiculopathy
A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy
The primary objectives of this clinical trial are to investigate the pharmacokinetics and safety of MDT-15 pellets in escalating sequential doses administered to different cohorts.
- Trial name
- NCT01917825
- Testing
- MDT-15
- Where
- 6 sites in United States
- Volunteers
- 54 people
- Sponsor
- Medtronic Spinal and Biologics
Cervical Radicular Pain
Interscalene and ıntertuberculary Pulsed Radiofrequency for Cervical Radiculopathy
This study examines the different application techniques of ultrasound-guided pulsed radiofrequency treatment of cervical spinal nerves for cervical radicular pain.
- Trial name
- NCT07112300
- Testing
- cervical nerve radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Lumbar Radiculopathy, Pain, Intractable
Radiocontrast Media in the Pulsed Radiofrequency Treatment
Pulsed radiofrequency applied to the dorsal root ganglion (DRG) is an interventional treatment alternative in the treatment of lumbar radicular pain that does not respond to conservative methods.
- Trial name
- NCT04876469
- Testing
- Pulsed Radiofrequency treatment of the lumbar dorsal root ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Cervical Radiculopathy, Cervical Spondylosis
Effectiveness of Cervical Transforaminal Epidural Steroid Injection
Study Purpose: This study is intended to monitor outcomes for 1 year following cervical TFESI. Based on current clinic volume and enrollment rates into a current study of cervical epidural injections that is nearing completion…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
- Trial name
- NCT04544683
- Testing
- Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Utah
Lumbar Disc Herniation
Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation
The aim of this study is to investigate the effectiveness of pulse magnetic field therapy on pain, functional status, and quality of life in patients with chronic radicular pain due to lumbar disc herniation.
- Trial name
- NCT04049812
- Testing
- PEMF, Hot pack, TENS
- Volunteers
- 50 people
- Sponsor
- Birkan Sonel Tur
Low Back Pain, Type of Leg Pain (Radicular, Non-radicular)
The Course of Low Back Pain
This study aims to research the possible associations of education level, sedentary lifestyle, and type of low back pain (radicular vs non-radicular) with the course of low back pain and recovery rate.
- Conditions
- Low Back Pain, Type of Leg Pain (Radicular, Non-radicular), Lifestyle (Sedentary Behavior and Physical Activity), Start Back Screening Tool
- Trial name
- NCT04419675
- Testing
- Observational Cohort, usual care = physical therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 347 people
- Sponsor
- Radboud University Medical Center
Neuropathic Pain Caused by Lumbar Radicular Pain
Effect of Minocycline on Pain Caused by Nerve Damage
The purpose of this study is to determine if minocycline is effective in the treatment of neuropathic pain. The effect of minocycline will be compared to the effect of placebo and amitriptyline.
- Trial name
- EMON (NCT01869907)
- Testing
- Minocycline, Amitriptyline
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Ziekenhuis Oost-Limburg
Pain
Effect of Acupuncture and Pain Medication on Radicular Pain Using QST
In this aim, we propose to conduct a double blinded, placebo-controlled, and randomized clinical trial to compare the clinical effectiveness of radicular pain relief by either acupuncture therapy or a course of pain medication…
- Trial name
- NCT01678586
- Testing
- Acupuncture, Gabapentin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Fatigue, Radicular Pain
Effects of Doxycycline on Persistent Symptoms Post-neuroborreliosis
The aim of this randomised, double-blind crossover study was to determine whether Doxycycline has an impact on the persistent symptoms post-neuroborreliosis, through alterations in the immune response and whether such an effect…
- Conditions
- Fatigue, Radicular Pain, Cognitive Dysfunction, Paresthesia
- Trial name
- NCT01205464
- Testing
- Doxycycline
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Linkoeping University
Low Back Pain, Radiculopathy
The Effect of Comorbid Psychiatric Conditions on Results of Transforaminal Epidural Steroid Injection
Low back pain (LBP) and radiculopathic pain are a major socio-economic problem affecting all age groups. 70% of people consult a doctor at least once in their life due to LBP.
- Trial name
- NCT03821350
- Testing
- Information leaflet
- Volunteers
- 166 people
- Sponsor
- Hitit University
Inflammatory Response, Radiculopathy
Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
This retrospective observational study aims to evaluate the predictive value of systemic inflammatory markers in determining treatment response in patients with lumbar radicular pain treated with a combination of pulsed…
- Conditions
- Inflammatory Response, Radiculopathy, Radiculopathy Lumbar, Chronic Pain
- Trial name
- NCT07495566
- Testing
- Lumbar Dorsal Root Ganglion Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people
- Sponsor
- Ankara Etlik City Hospital
Lumbar Radicular Pain, Artifical Intelligence
MRI-Based Artificial Intelligence Prediction of Fluoroscopic C-Arm Angles for Lumbar Transforaminal Epidural Steroid Injections
This study aims to prospectively evaluate the accuracy of artificial intelligence (AI) in predicting fluoroscopic C-arm oblique and craniocaudal angles from pre-procedural lumbar magnetic resonance (MR) images for lumbar…
- Trial name
- NCT07875855
- Testing
- AI based evaluation
- Volunteers
- 80 people
- Sponsor
- Marmara University
Cervical Radiculopathy, Cervical Radicular Pain
Effect of Myofascial Release Technique in Patients with Unilateral Cervical Radiculopathy
The aim of the study is to investigate the effectiveness of myofascial release technique on pain, range of motion, muscle strength, functionality and quality of life in individuals diagnosed with cervical radiculopathy with…
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Cervical; Hernia, Cervical Disc Disease
- Trial name
- NCT04597112
- Testing
- Myofascial Release Technique, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Cervical Radicular Pain, Cervical Radiculopathy
Predictors of Response to Manual Physiotherapy Using Somatosensory Profiles in Patients With Cervicobrachial Pain
The goal of this clinical trial is to investigate about the characteristics that predict response to physiotherapy treatment in patients with nerve related neck arm pain.
- Conditions
- Cervical Radicular Pain, Cervical Radiculopathy, Cervical Pain
- Trial name
- NCT06069362
- Testing
- Manual physiotherapy and neurodynamic exercises
- Where
- Spain
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Breast Cancer, Pain, Postoperative
Erector Spinae Plane Block Versus Paravertebral Block
This study aims to compare the effectiveness of paravertebral block and erector spinae plane block after mastectomy. The primary objective of this randomized controlled trial is to demonstrate equivalent dermatomal spread for…
- Conditions
- Breast Cancer, Pain, Postoperative, Anesthesia, Local
- Trial name
- NCT03471442
- Testing
- Paravertebral block, Erector spinae plane block, General anesthetic
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Low Back Pain
Intraarticular Lumbar Joint Corticosteroid Injection(s) as a Treatment of Chronic Low Back Pain in a Selected Population
Subjects (N=120) who have had non-radicular low back pain, believed by clinical assessment and imaging to be consistent with lumbar zygapophysial joint (Z-joint) generated pain, who have failed conservative therapy including…
- Trial name
- NCT01382771
- Testing
- Intra-articular corticosteroid injection, Intra-articular saline injection
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Florida
Transforaminal Epidural Steroid Injection, Radicular Low Back Pain
Efficacy of TFESI in Lumbar Radicular Pain
The goal of this retrospective study is to evaluate the effectiveness of transforaminal epidural steroid injections (TFESI) in patients with radicular low back pain caused by lumbar disc herniation who did not improve with…
- Trial name
- NCT07538765
- Testing
- transforaminal epidural steroid injections (TFESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- Ankara City Hospital Bilkent
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Dorsal Root Ganglion Intervention Treatments
This study applies 3D-printed customized guide plate in assisting the accurate puncture in transforaminal epidural steroid injection (TFESI) combined with pulsed radiofrequency (PRF) treatment.
- Trial name
- NCT05403775
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital