Clinical trials: Radical Prostatectomy
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Low Intensity Shockwave Therapy for Erectile Dysfunction
Low-intensity shockwave therapy (LiSWT) has been deemed "a safe and well-tolerated procedure but its efficacy for the treatment of ED is doubtful and deserves more investigation" by the European Society of Sexual Medicine.
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Radiation Therapy, Erectile Dysfunction Due to General Medical Condition
- Trial name
- NCT04434352
- Testing
- Storz Duolith Low-Intensity Shockwave Therapy
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Prostate Cancer, Post Prostatectomy Incontinence
Anatomical and Functional Differences Between Continent and Incontinent Men Post Radical Prostatectomy
One out of every six men will be diagnosed with prostate cancer and post prostatectomy up to 75% report urinary incontinence. There are many hypotheses about the exact cause of post prostatectomy stress incontinence (PPI).
- Trial name
- NCT01832831
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Erectile Dysfunction, Post-Op Complication
Low-energy Extracorporeal Shockwave Treatment for Patients After Radical Prostatectomy
The purpose of this project is to verify the relationship between low intensity shock wave treatment (LI-SWT) and increased scores in self-assessment regarding to erectile function (ED) and sexual intercourse, in patients, who…
- Conditions
- Erectile Dysfunction, Post-Op Complication, Prostatic Diseases
- Trial name
- NCT03192917
- Testing
- Low intensity extracorporeal shock wave treatment (LI-ESWT)
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
PROSTATECTOMY, URINARY INCONTINENCE
EFFECT ON QUALITY OF LIFE AFTER PROSTATECTOMY
Aim: This study was conducted to determine the effect of pelvic floor exercises (PTE) on urinary incontinence and quality of life (QOL) after radical prostatectomy (RP).
- Trial name
- NCT05700487
- Testing
- PELVIC FLOOR EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Urinary Incontinence, Quality of Life
Bladder Training in Radical Prostatectomy
Radical prostatectomy is the gold standard in the treatment of patients with localized prostate cancer. Urinary incontinence, which is common after surgery, can affect the quality of life of men negatively.
- Conditions
- Urinary Incontinence, Quality of Life, Lower Urinary Tract Symptoms
- Trial name
- NCT04628351
- Testing
- Bladder Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Prostate Cancer, Urinary Incontinence, Urge
Effects of Urinary Bladder Hypertrophy on Urge Urine Incontinence After Radical Prostatectomy
This study is designed to evaluate men before radical prostatectomy for the incidence of Overactive Bladder (OAB), as well as urge urine incontinence (UUI) development after the surgery.
- Conditions
- Prostate Cancer, Urinary Incontinence, Urge, Incontinence, Prostatectomy
- Trial name
- NCT03061760
- Testing
- Radical prostatectomy, Initial evaluation, Evaluation after 1,3,6,9,12 months
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Collegium Medicum w Bydgoszczy
Low Flow Anesthesia, Normal Flow Anesthesia
Comparison of Low and Normal Flow Anesthesia in Robotic Assisted Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy has gained increasing popularity compared to open radical prostatectomy with its advantages such as low blood loss, reduced blood transfusion rate, low complication rate, and…
- Conditions
- Low Flow Anesthesia, Normal Flow Anesthesia, Robotic Surgery
- Trial name
- NCT05517551
- Testing
- robotic assisted radical prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Prostate Cancer Patients Undergoing Radical Prostatectomy, Prostate CA
Research on PSMA-Targeted Intraoperative Fluorescent Imaging Agents
Phase I: Primary Research Objective: Evaluate the safety, tolerability, and pharmacokinetic characteristics of a single dose of DGPR1008 in healthy subjects.
- Trial name
- DGPR1008 (NCT07101354)
- Testing
- 0.01mg/kg DGPR1008 Injection Dose Group 1 (n=6), 0.02mg/kg DGPR1008 Injection Dose Group 2 (n=6), 0.04mg/kg DGPR1008 Injection Dose Group 3 (n=6)
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Haitao Niu, MD
Urinary Incontinence, Prostate Cancer
Perioperative Post-Prostatectomy Incontinence Home Telehealth Program
Many men develop urine leakage after prostate cancer surgery. Usually it is temporary, but pelvic floor muscle training and exercise (including urine control strategies) have been shown to reduce the time to regaining urine…
- Trial name
- ProsTel (NCT01960998)
- Testing
- Pelvic Floor Muscle Training, Perioperative Care and Wetness Management
- Where
- 3 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Clinical Competence
Laypersons Cannot Select Preferred Surgeon Based on Videos of Simulated Robot-assisted Radical Prostatectomies
The goal of this comparative blinded assessment study is to compare ratings of crowd workers and expert ratings in simulated robot-assisted radical prostatectomies The main question[s] it aims to answer are: to examine the use of…
- Trial name
- NCT05607485
- Testing
- Randomized video numbers
- Where
- Denmark
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Plane Block in Retropubic Radical Prostatectomy
This study will define the postoperative analgesic effect of ESP block via amount of patient-controlled analgesia (PCA) and postoperative analgesic consumption (such as routinely and rescue analgesics) and compare the control…
- Trial name
- NCT03413163
- Testing
- Ultrasound guided erector spinae plane block, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Robot-Assisted Radical Prostatectomy
Effect of Control Ventilation, PEEP, and PEEP With ARM in Robot-assisted Radical Prostatectomy
The goal of this clinical trial is to determine whether different ventilatory strategies improve oxygenation and hemodynamic stability in patients undergoing robot-assisted radical prostatectomy under general anesthesia.
- Trial name
- NCT07462689
- Testing
- PEEP group, PEEP + ARM group
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ilsan Cha hospital
Positive Pressure Ventilation
Flow- Versus Volume-controlled Ventilation During Robot-assisted Laparoscopic Radical Prostatectomy
During robot-assisted laparoscopic radical prostatectomy (RALRP), patients are placed under general anesthesia and supported with mechanical ventilation.
- Trial name
- NCT07453810
- Testing
- Flow-Controlled Ventilation, Volume-Controlled Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Prostate Cancer
Prostate Cancer - Patient Empowerment Program
Each year over 20,000 men are diagnosed with prostate cancer in Canada with the majority undergoing some form of treatment option.
- Trial name
- PC-PEP (NCT03660085)
- Testing
- PC-PEP
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Safety, Tolerability and Pharmacokinetics (PK) Evaluation of BZ371A, Topically Administered
The purpose of this study is to evaluate pharmacokinetics, safety and tolerability profile of BZ371A topically administered in healthy patients.
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction, Prostate Cancer, Radical Prostatectomy
- Trial name
- NCT05332340
- Testing
- BZ371A
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Biozeus Biopharmaceutical S.A.
Prostate Cancer, Anesthesia
Low-flow Versus Minimal-flow Sevoflurane Anesthesia During Robot-assisted Laparoscopic Radical Prostatectomy
Study Synopsis This protocol is formatted for ClinicalTrials.gov-style registration and manuscript-facing documentation. It is based on the uploaded Turkish ethics protocol and keeps the original core design: comparison of…
- Conditions
- Prostate Cancer, Anesthesia, Respiratory Mechanics
- Trial name
- NCT07475533
- Testing
- Common Anesthetic Management
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Post Radical Prostatectomy Urinary Incontinence
Efficacy of Extracorporeal Magnetic Stimulation, Pelvic Floor Muscle Exercise, and Combination of Both in Management of Post Radical Prostatectomy Urinary Incontinence
Urinary incontinence is one of the most common complications of radical prostatectomy. Multiple prevention and treatment modalities have been proposed in the management of post prostatectomy urinary incontinence.
- Trial name
- NCT05680168
- Testing
- Extracorporeal electromagnetic stimulation, Pelvic floor exercises
- Where
- Qatar
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamad General Hospital