Clinical trials: Radical Gastrectomy
Gastric Cancer
ERAS for Gastric Cancer Patients After NACT
Background: Gastric cancer patients receiving neoadjuvant chemotherapy (NACT) are more vulnerable to perioperative stress. Enhanced recovery after surgery (ERAS) is widely used in surgical patients aiming at reducing stress…
- Trial name
- NCT06365814
- Testing
- enhanced recovery after surgery, conventional perioperative management
- Where
- China
- Volunteers
- 252 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Gastrectomy, Gastric Carcinoma
The Influence of Splenic Artery Characteristics in Gastric Cancer Surgery
The northwest Chinese population has unique anatomical characteristics of splenic artery due to ethnic differences, which has an important impact on the development and prognosis of laparoscopic radical total gastrectomy.
- Trial name
- NCT06680362
- Where
- China
- Volunteers
- 176 people
- Sponsor
- xiaohua li
The Effect of BIS Closed-loop Target Control on Postoperative Operation
Effects of BIS Closed Loop Target Controlled Infusion on Perioperative Inflammatory Response and Prognosis of Elderly Patients Undergoing Laparoscopic Radical Gastrectomy for Gastric Cancer
The purpose of this study is to find the elderly patients with laparoscopic gastric cancer radical is suitable the BIS closed round target control level of anesthesia depth of sedation, can decrease the elderly laparoscopic…
- Trial name
- NCT05173909
- Testing
- BIS closed-loop target controlled infusion
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Zhonghua Chen,MD
Gastric Cancer, Gastro-oesophageal Junction Cancer
Liquid Biopsy in Monitoring the Neoadjuvant Chemotherapy and Operation in Gastric Cancer
To explore the clinical value of dynamic detection of circulating tumor cells(CTCs), circulating tumor DNA(ctDNA) and cell-free DNA(cfDNA) in neoadjuvant chemotherapy and operation of resectable or locally advanced gastric or…
- Trial name
- NCT03957564
- Testing
- Neoadjuvant chemotherapy with PSOX regimen., Detect the imaging data and levels of CTC, ctDNA, cfDNA, CEA, CA19-9, CA72-4 in plasma., Detect the tumor related DNA in pathological tissues after operation.
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Affiliated Hospital of Qinghai University
Esophagogastric Junction Adenocarcinoma, Siewert Type II Adenocarcinoma of Esophagogastric Junction
A Prospective Clinical Study of Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Ⅱ AEG
Objective: To evaluate the safety, feasibility and clinical efficacy of transthoracic single-hole assisted laparoscopic radical gastrectomy for Siewert Type Ⅱ adenocarcinoma of esophagogastric junction.
- Trial name
- NCT04423354
- Testing
- Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Type Ⅱ Adenocarcinoma of Esophagogastric Junction
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Gastric Adenocarcinoma Patients, Who Are Scheduled for Laparoscopic Radical Gastrectomy
Comparison of Safety and Clinical Effects of Straight and Articulated Instruments (ArtiSential) in Laparoscopic Gastrectomy for Gastric Cancer Patients, a Prospective Randomized Study
In patients with gastric cancer, gastrectomy can be performed via laparoscopic/robotic or open surgery. It is crucial to completely remove the tumor along with an adequate extent of lymph node dissection.
- Trial name
- NCT07100431
- Testing
- Articulating (experimental group), Control (control group)
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Gangnam Severance Hospital
Pancreatic Fistula
Comparison of Effectiveness of TissuePatchTM in Preventing Postoperative Pancreatic Fistula
Postoperative pancreatic fistula is one of the most serious complications after gastric cancer surgery and can lead to surgery-related death.
- Trial name
- NCT05404256
- Testing
- Radical gastrectomy +D2 lymphadenectomy+TissuePatchTM to seal pancreatic tissue surface, Radical gastrectomy +D2 lymphadenectomy
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Cancer, Roux-en-y Anastomosis Site
Roux-en-Y vs. Roux-en-Y+ Pouch for D2 Total Gastrectomy
Gastric is one of the most prevalence digestive malignance tumors in China. Radical resection of primary tumors and combine with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Gastric Cancer, Roux-en-y Anastomosis Site, Gastric Anastomosis (Site), Quality of Life
- Trial name
- WCGCC-1202 (NCT02110628)
- Testing
- Roux-en-Y anastomosis, Roux-en-Y+Pouch anastomosis
- Where
- 9 sites in China
- Volunteers
- 588 people
- Sponsor
- West China Hospital
Gastrostomy Complications
Radical Gastrectomy Within Enhanced Recovery Programs(ERAS): a Prospective Randomized Controlled Trial
This study is a prospective, single-center, randomized controlled trial. The study protocol was approved by the Ethics Committee at the First Hospital of Jilin University.ERAS is combined with the laprascopic gastrectomy to…
- Trial name
- NCT03046303
- Testing
- ERAS
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The First Hospital of Jilin University
STOMACH NEOPLASM, Robotic Surgical Procedures
Safety and Efficacy Evaluation of Single-Port Versus Multi-Port Robotic-Assisted Radical Distal Gastrectomy for Gastric Cancer
This multicenter randomized non-inferiority trial evaluates single-port versus multi-port robotic-assisted radical distal gastrectomy in patients with gastric cancer.
- Trial name
- NCT07828899
- Testing
- Single-Port Robot-Assisted Radical Distal Gastrectomy, Multi-Port Robot-Assisted Radical Distal Gastrectomy
- Where
- 5 sites in China
- Volunteers
- 212 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Proximal Gastric Adenocarcinoma, Reconstruction
A Prospective Observation Registry Study on the Alimentary Reconstruction After Radical Proximal Gastrectomy
This study is designed as a prospective, real world registry study that compare the safety and efficacy of the different construction methods after radical proximal gastrectomy.
- Trial name
- STAR-PG01 (NCT05539105)
- Testing
- Double tract reconstruction, Gastric conduit reconstruction, Other reconstructions
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastric Cancer, GastroEsophageal Cancer
Comparison Between Double Tract Anastomosis and Esophagogastrostomy After Radical Proximal Gastrectomy
The patients with upper gastric cancer (cT1N0M0) or gastroesophageal adenocarcinoma (diameter less than 4 cm) will be enrolled into this study.
- Trial name
- NCT03613142
- Testing
- Double tract anatomosis, Esophagogastrostomy
- Volunteers
- 202 people
- Sponsor
- Peking University Cancer Hospital & Institute
Advanced Gastric Adenocarcinoma
Efficacy of HIPEC in the Treatment of Patients With Locally Advanced Gastric Cancer
The purpose of this study is to study the efficacy of hyperthermic intraperitoneal chemotherapy in the treatment of patients with locally advanced gastric cancer after radical gastrectomy with D2 lymphadenectomy.
- Trial name
- HIPEC (NCT02240524)
- Testing
- D2 lymphadenectomy, Systemic chemotherapy, HIPEC
- Where
- China
- Volunteers
- 582 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Gastric or Esophagogastric Junction Adenocarcinoma
PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer
This multicenter, randomized, double-blind phase III study intends to recruit about 878 patients, including PD-L1 positive 660 patients, who have received radical gastrectomy (R0 resection, D2 or more extended lymphadenectomy)…
- Trial name
- NCT05180734
- Where
- 71 sites in China
- Volunteers
- 878 people
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Gastric Cancer, Gastroesophageal Junction Cancer
Robotic Versus Laparoscopic Radical Surgery for Locally Advanced Gastric Cancer
This [Study Type: Clinical Trial] aims to [Primary Objective: evaluate the long-term efficacy and safety of robotic gastrectomy for locally advanced gastric cancer] in [Participant Population: patients with locally advanced…
- Trial name
- NCT06791538
- Testing
- Robotic Gastrectomy, Laparoscopic Gastrectomy
- Where
- 2 sites in China
- Volunteers
- 740 people
- Sponsor
- Southwest Hospital, China
Gastric Cancer, Gastrointestinal Disease
Efficacy and Safety of Hou Gu Mi Xi in Patients With Spleen Qi Deficiency and Radical Gastrectomy for Gastric Cancer
This trial aims to determine whether Hou Gu Mi Xi is an effective treatment for improving symptoms and indicators in patients with spleen qi deficiency and radical gastrectomy for gastric cancer.
- Trial name
- NCT03025152
- Testing
- Hou Gu Mi Xi
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Gastric Cancer
Development and Validation of a Web-based Nomorgam to Predict Postoperative Complications
The incidence of complications after gastrectomy remains high among elderly patients with gastric cancer. The investigators sought to establish and validate a web-based nomorgam for predicting total complications among elderly…
- Trial name
- NCT05301699
- Testing
- data analysis; validating the nomogram
- Where
- China
- Volunteers
- 582 people
- Sponsor
- Nanjing Medical University
Gastrectomy, Postoperative Analgesia
Efficacy and Safety of Anrikefon Injection for the Treatment of Postoperative Pain in Patients Undergoing Totally Laparoscopic Radical Distal Gastrectomy
Anruikefen is a peripherally highly selective kappa receptor agonist that does not easily cross the blood-brain barrier, resulting in a low incidence of central adverse reactions such as respiratory depression, sedation, and…
- Trial name
- NCT07330063
- Testing
- Anruikefen (Intravenous Bolus), Anruikefen (Intravenous Infusion)
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Gastric Cancer, Chemotherapy, Adjuvant
The Efficacy of PIPAC and Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients.
The goal of this randomized clinical trial is to investigate whether pressurized intraperitoneal chemotherapy (PIPAC), delivered immediately after minimally invasive D2 gastrectomy and repeated 6-8 weeks later, improves 12-month…
- Conditions
- Gastric Cancer, Chemotherapy, Adjuvant, Peritoneal Metastases, Minimally Invasive Surgical Procedures
- Trial name
- EPICURE (NCT06295094)
- Testing
- Cisplatin, Doxorubicin
- Where
- 5 sites in United States, Denmark and 3 more
- Volunteers
- 264 people
- Sponsor
- Odense University Hospital
Adhesive Intestinal Obstruction
Anti-adhesion Effect of GUARDIX-SGⓇ in Gastric Cancer Surgery
This study is to evaluate the efficacy of GUARDIX-SGⓇ for patients with gastrectomy in Korea and the investigators hypothesized applying of adhesive preventing agent would reduce incidence of adhesive obstruction after…
- Trial name
- NCT02198898
- Testing
- GUARDIX-SG
- Where
- South Korea
- Volunteers
- 224 people
- Sponsor
- The Catholic University of Korea