Clinical trials: RHINOPLASTY
Hypotension, Surgery-Complications
The Effects of Nicardipine and Esmolol Applied for Controlled Hypotension
In this study, the effects of nicardipine and esmolol applied for controlled hypotension in rhinoplasty on hemodynamics and regional renal oxygenation will be investigated.
- Conditions
- Hypotension, Surgery-Complications, Oxygen Deficiency
- Trial name
- NCT05430724
- Testing
- Controlled hypotention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Yuzuncu Yil University
Nasal Deformity, Rhinoplasty
Patient-Reported Outcomes and Complications After Structural Rhinoplasty Using Septal Extension Grafts
Structural rhinoplasty with septal extension graft (SEG) is commonly used to achieve stable nasal tip support and predictable long-term outcomes.
- Conditions
- Nasal Deformity, Rhinoplasty, Nasal Obstruction
- Trial name
- SEG-PROM (NCT07531810)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University Hospital
RHINOPLASTY, NASAL SURGICAL PROCEDURES
Chronic Rhinosinusitis Classification Proposal
Chronic rhinosinusitis (CRS) is a debilitating disease that remains (smell, nasal patency, flow) because currently treatment protocols available to us are with a limited efficacy.
- Trial name
- NCT02822781
- Testing
- No intervention
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hypotensive Anesthesia
Regional Block of the Nose for Hypotensive Anaesthesia in Septo-rhinoplasty
Septorhinoplasty is a cosmetic surgery that many people are choosing to undergo. It can be done under general anesthesia, twilight anesthesia or regional anesthesia.
- Trial name
- NCT03774693
- Testing
- General anesthesia with fentanyl boluses, Regional block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Rhinoplasty
Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty
The purpose of this study is to determine efficacy, safety, and ease of cartilaginous grafting using polydioxanone (PDS) plates in comparison to non-plated cartilaginous grafts as performed through an endonasal rhinoplasty…
- Trial name
- NCT01225250
- Testing
- Polydioxanone (PDS) plates, Caudal septal extension graft performed through endonasal rhinoplasty
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- DeNova Research
Bleeding Reduction
Low vs. Very Low Dose of Prophylactic Tranexamic Acid for Bleeding Reduction During Rhinoplasty
The purpose of this study is to determine whether very low dose of preoperative tranexamic acid (5mg/kg) is as effective as low dose (10mg/kg) for intraoperational bleeding reduction in patients undergoing elective rhinoplasty…
- Trial name
- NCT03070847
- Testing
- Tranexamic Acid, Sodium Chloride
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bartłomiej Wódarski
Anesthesia, Hypothermia
Comparisons of Two Different Type Heater in Different Inhalation Anesthesia in Terms of Prevention of Hypothermia
Unintentional perioperative hypothermia is a common occurrence. One of the recommendations of the guidelines to prevent hypothermia is the use of active warmers.
- Conditions
- Anesthesia, Hypothermia, Heat
- Trial name
- NCT06107647
- Testing
- COVIDIEN WarmTouch
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty
Unilateral Septal Extension Graft and Bilateral Septal Extension Graft in Droopy Tip and Its Effect on Tip Deviation
This study aims to compare between the unilateral and bilateral septal extension graft and evaluate the effect of each of them on tip deviation.
- Conditions
- Septal Extension Graft in Rhinoplasty, Primary Rhinoplasty, Nasal Projection
- Trial name
- NCT07446426
- Testing
- Unilateral septal extension graft, Bilateral septal extension graft
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Anesthesia
Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty
To compare the effect of intramuscular dexmedetomidine versus oral gabapentin premedication on the emergence agitation after rhinoplasty.
- Trial name
- NCT05626998
- Testing
- Dexmedetomidine, Gabapentin
- Where
- Egypt
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Rhinoplasty
Effect of Systemic Inflammatory Index and Systemic Immune Inflammation Index on Ecchymosis, Bleeding and Edema
Rhinoplasty is a cosmetic surgical procedure that is widely applied today and is characterized by edema in the postoperative period.
- Trial name
- NCT06649370
- Testing
- Hypotensive Drugs and/or Vasoactive Drugs
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Rhinoplasty, Dexmedetomidine
Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty
The investigators compared the effects of remifentanil and dexmedetomidine administered under general anesthesia on hemodynamics, postoperative pain, recovery, postoperative nausea, vomiting, shivering, patient's and surgeon's…
- Conditions
- Rhinoplasty, Dexmedetomidine, Remifentanil
- Trial name
- NCT05572723
- Testing
- Remifentanil 2 MG, dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Subjects Requesting and Requiring an Open Rhinoplasty
A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty
Rhinoplasty (nasal reconstruction i.e. "a nose job") is a surgical procedure performed on the nose to correct a medical problem or change the appearance of the nose.
- Trial name
- NCT01684020
- Testing
- ARTISS human fibrin sealant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- DeNova Research
Cleft Lip and Cleft Palate
Aesthetic and Functional Self-Assessment Following Rhinoseptoplasty in Patients With Unilateral Cleft Lip and Palate
Secondary rhino-septoplasty in unilateral cleft lip and palate is the treatment of choice for the correction of aesthetic deformities and the functional impact on ventilation nasal. It remains a difficult treatment.
- Trial name
- RHINOFENTE (NCT07048418)
- Testing
- Mailing and completing CLEFT-Q and NOSE questionnaires
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Nasal Defect
Non-Surgical Rhinoplasty Using PDO Threads
To determine the effects of absorbable Polydioxanone (PDO) thread non-surgical revision rhinoplasty on first impressions and quality of life (FACE-Q scale) in 10 patients who desire further changes to their nasal tip and/or nasal…
- Trial name
- NCT04769427
- Testing
- PDO max threads
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DeNova Research
Rhinoplasty
The Effect of Different Bed Head Heights on Patients After Rhinoplasty
This study will be conducted to evaluate the effect of different bed head heights (thirty degrees and forty-five degrees) given to patients after rhinoplasty surgery on periorbital edema, periorbital ecchymosis, respiratory…
- Trial name
- NCT05695794
- Testing
- the group with a bed head height of 45 degrees, the group with a bed head height of 30 degrees
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Rhinoplasty, Depth of Anesthesia
Processed EEG Monitoring During Controlled Hypotension in Patients Undergoing Rhinoplasty
This prospective observational study evaluates intraoperative processed electroencephalography parameters in adult patients undergoing elective rhinoplasty under total intravenous anesthesia with controlled hypotension.
- Conditions
- Rhinoplasty, Depth of Anesthesia, Surgical Bleeding, Postoperative Recovery
- Trial name
- NCT07671781
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Gazi University
Nose Deformities, Acquired
Mastoid Bone Autograft for Dorsal Nasal Augmentation
The purpose of this study is to evaluate the safety and efficacy of mastoid bone autograft for dorsal nasal augmentation in rhinoplasty.
- Trial name
- NCT00545428
- Testing
- Rhinoplasty
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Federal University of Uberlandia
Pain, Postoperative, Opioid Use
A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty
Adding a single preoperative dose of gabapentin to the standard pain regimen will reduce postoperative opioid consumption within the first 72 hours in patients undergoing rhinoplasty.
- Trial name
- NCT03498261
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pain, Postoperative, Local Anesthetic
The Utility of Long-acting Local Anesthetic Agents in Reducing Post-operative Opioid Requirements Following Rhinoplasty
On average, more than 130 Americans die every day from opioid overdose. Surgeons provide 37% of all opioid prescriptions in the United states, second only behind pain management physicians.
- Trial name
- NCT04377204
- Testing
- marcaine bupivacaine, Lidocaine
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Rhinoplasty Techniques
Hybrid Osteoplasty Versus Osteotomy in Rhinoplasty
This study is designed to compare two common techniques for reducing the nasal hump during rhinoplasty: the traditional method using osteotomes and rasps, and a newer technique called hybrid osteoplasty that uses a surgical…
- Trial name
- NCT07142525
- Testing
- Hybrid Osteoplasty, Traditional Osteotomy and Rasping
- Where
- Iraq
- Volunteers
- 200 people
- Sponsor
- University of Sulaimani