Clinical trials: Pulse Pressure Variation
Hypotension on Induction
PPV for Predicting PIH in the Elderly
The purpose of this observational study is to investigate the predictive power of pulse pressure variability during forced inhalation（PPVfi） on the occurrence of hypotension in elderly patients after induction of general…
- Trial name
- PPVfi-PIH (NCT07166562)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Brain Tumor Adult, Pulse Pressure Variation
Pulse Pressure Variation vs. Central Venous Pressure for Fluid Management in Intracranial Tumor Surgery
This study investigates the efficacy of pulse pressure variation (PPV) compared to central venous pressure (CVP) in guiding fluid management during intracranial tumor surgeries.
- Conditions
- Brain Tumor Adult, Pulse Pressure Variation, Central Venous Pressure, Fluid Management
- Trial name
- PPV-CVP-FLUID (NCT06776666)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Surgery
Intraoperative Fluid Management Based on Arterial Pulse Pressure Variation During High-Risk Surgery
Hypovolaemia and tissue hypoperfusion can pass undetected during and after major surgery. The resulting systemic inflammatory response and organ dysfunction, often not clinically apparent for several days, may lead to increased…
- Trial name
- NCT00479011
- Testing
- fluid management based on arterial pulse pressure variation
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Santa Casa de Passos
Spine Disease
GDFT Based on PPV Compared With Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: RCT
The investigators will do the Goal directed fluid therapy by protocolized fluid management in the experimental group, using PPV to guide the fluid administration, compare with standard fluid management in patients undergoing…
- Trial name
- NCT03164811
- Testing
- goal directed fluid therapy, Controlled
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Systemic Inflammatory Response Syndrome, Circulatory Failure
Accuracy of Pulse Pressure Variations Measured by a Non Invasive Digital Device to Predict Fluid Responsiveness
It has been well established that only 40 to 60% of the patients hospitalized for inflammatory response syndrome (SIRS) positively respond to volume expansion (VE).
- Conditions
- Systemic Inflammatory Response Syndrome, Circulatory Failure, Mechanical Ventilation
- Trial name
- NCT03066388
- Testing
- Pulse pressure variations
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
Patients Receiving Protective Lung Ventilation, Patients in Grey Zone (3 < Pulse Pressure Variation (PPV) < 17
A Functional Test to Assess Fluid Status During Lung Protective Ventilation Strategies
Dynamic preload indices, such as pulse pressure variation (PPV) and stroke volume variation (SVV) are generally accepted as accurate indicator of fluid responsiveness in mechanically ventilated patients.
- Trial name
- NCT04118244
- Testing
- lung recruitment maneuver
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Fluid Responsiveness
Pneumoperitoneum and Trendelenburg Position on Fluid Responsiveness
The increased intraabdominal pressure and intrathoracic pressure due to pneumoperitoneum negatively affect the cardiovascular system, relatively dynamic parameters may vary due to intraoperative fluid therapy.
- Trial name
- NCT04060069
- Testing
- Ringer Lactate
- Volunteers
- 45 people
- Sponsor
- Kocaeli University
Fluid Responsiveness Predictability, Hemodynamic Monitoring
Comparison of Acoustic Variability Index (AVI) and Pulse Pressure Variation (PPV) for Predicting Fluid Responsiveness in Mechanically Ventilated Patients
The goal of this clinical trial is to learn if a new medical device called ResQ works to predict fluid needs in adults undergoing surgery under general anesthesia.
- Conditions
- Fluid Responsiveness Predictability, Hemodynamic Monitoring, Anesthesia, General
- Trial name
- NCT07516470
- Testing
- Biological Signal Processing Device for Acoustic Variability Index, Patient monitor for pulse pressure variation, Hemodynamic monitor for cardiac Output and stroke volume variation
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Signal House Co., Ltd.
Multiple Organ Failure, Intensive Care Unit Syndrome
The Blood Pressure Analysis on Critically Ill Patients
The study is to explore the relationship between coefficient of variation of harmonic magnitude (HCV) and different organ failures among those critically ill patients.
- Trial name
- NCT03827369
- Testing
- ICU patient
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taoyuan General Hospital
Prone Position, Blood Volume
The Effect of High vs. Low Fluid Volume on Ocular Parameters in Prone Spine Surgery
The purpose of this trial is to compare the effect of different fluid volume infusion on ocular parameters in patients undergoing spine surgery in prone position.
- Conditions
- Prone Position, Blood Volume, Intraocular Pressure
- Trial name
- NCT03890510
- Testing
- Ringer's Lactate solution, Spine surgery under general Anesthesia in the prone position
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Huashan Hospital
Labor, Epidural Analgesia
Pulse Pressure Variability With Position Before EPIdural Analgesia
Fetal heart rate abnormalities are common. Miller et al. have demonstrated that new onset fetal heart rate abnormalities after initial labor epidural dosing occur more frequently in women with a low admission pulse pressure than…
- Trial name
- PP-PERI (NCT03126136)
- Testing
- Nicom (TM)
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- Hopital Foch
Surgery
Fluid Challenges and Microcirculation
The goal of this prospective observational study is to assess the impact of fluid challenge administration on macro and microcirculation in patients situated in the gray zone during a high risk abdominal surgery
- Trial name
- FC (NCT04559178)
- Testing
- Fluid challenge
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Erasme University Hospital
General Anesthesia
The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position
The purpose of this study is to investigate the validity of pulse pressure variation to predict fluid responsiveness in patients undergoing robotic or laparoscopic gastrectomy.
- Trial name
- NCT02771067
- Testing
- Fluid infusion
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) - "HemodynamECMOnitoring-VA Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593756
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Hypovolemia
Correlation Between ΔPP/HR and ΔSV During Fluid Challenge.
In high perioperative risk patients, guidelines suggest intraoperative haemodynamic optimization by measurement of stroke volume (SV) to guide fluid resucitation.This strategy requires an invasive monitoring and learning.
- Trial name
- ΔPP/HRvsΔSV (NCT02439242)
- Testing
- fluid challenge of saline
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Hemodynamic Monitoring
Changes of Pulse Pressure Variation Duing Tidal Volume Challenge in Patients With Spontaneous Breathing
Background: Predicting preload responsiveness by using dynamic indicators before administering fluids to critically ill patients is nowadays routinely performed at the bedside.
- Trial name
- NCT04369027
- Testing
- passive leg raising
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hopital Antoine Beclere
Pleth Variability Index, Lung Recruitment Maneuver
Evaluation of Fluid Responsiveness With Pulse Variation Index and Systolic Blood Pressure Changes After Lung Recruitment Maneuver
Evaluation of Fluid Responsiveness With Pulse Variation Index and Systolic Blood Pressure Changes After Lung Recruitment Maneuver
- Conditions
- Pleth Variability Index, Lung Recruitment Maneuver, Fluid Responsiveness
- Trial name
- NCT04939129
- Testing
- The research is terminated by calculating the percentage of PVI changes with SAB formed by LRM after fluid challenge.
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ankara City Hospital Bilkent
Brain Tumor, Craniotomy
Intraoperative Goal Directed Fluid Management in Supratentorial Brain Tumor Craniotomy
Pulse pressure variation (PPV) to standard fluid management (4ml/Kg/hr) in patients undergoing supratentorial mass excision. The investigators hypothesize that in these procedures, goal-directed fluid therapy (GDT) might improve…
- Trial name
- NCT03033706
- Testing
- Pulse pressure variation guided fluid therapy, Traditional fluid therapy, Brain tumor excision
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Ventricular Dysfunction
Hemodynamic Indices Predictive of a Beneficial Response to Fluid Expansion in Case of Hemodynamic Failure After Cardiac Surgery With Altered Preoperative Ejection Fraction (LVEF≤45%)
Low Cardiac Output Syndrome occurs frequently after cardiac surgery, especially when pre-operative LVEF is altered (LVEF≤45%). The correction of hemodynamic failure requires adapted treatments: fluid expansion and/or inotropic or…
- Trial name
- ALTERVOL (NCT01673230)
- Testing
- cardiac surgery for ventricular dysfunction
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Fluid Responsiveness
Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery
The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children.
- Trial name
- NCT01364103
- Testing
- volume expansion
- Where
- 2 sites in South Korea
- Volunteers
- 33 people
- Sponsor
- Seoul National University Hospital