Clinical trials: Pulpitis - Irreversible
Asymptomatic Irreversible Pulpitis
Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment
To Determine Effect Of Apical Third enlargement To Different Taper And Master Apical Preparation Size On Periapical Healing And Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment : A Randomized…
- Trial name
- NCT07166679
- Testing
- root canal treatment with 2% taper, root canal treatment with 4% taper, root canal treatment with 6 %taper
- Where
- India
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Irreversible Pulpitis
Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar
The goal of this clinical trial is to compare between post operative pain and oral health related quality of life in participants receiving two treatments for first permanent mandibular molars with poor prognosis.
- Trial name
- NCT06420583
- Testing
- MTA pulpotomy, Extraction
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Reversible Pulpitis
Treatment of Deep Carious Lesions With Selective Caries Removal, Partial or Full Pulpotomy
The optimal treatment of deep caries lesions extended to the inner third of dentin is still under discussion. Cariologists prefer selective caries removal, meanwhile endodontists recommend partial pulpotomy.
- Conditions
- Irreversible Pulpitis, Reversible Pulpitis, Dentine Caries
- Trial name
- Vitapulp (NCT04807244)
- Testing
- Selective Caries Removal with Biodentine™, Partial Pulpotomy with Biodentine™, Full Pulpotomy with Biodentine™
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Pulpitis - Irreversible
The Effect of Prognostic Factors on the Success of Full Pulpotomy in Permanent Mature Molars With Irreversible Pulpitis
This study aims to evaluate the effect of prognostic factors, such as the degree of pulpal inflammation and the radiographic caries depth, on the success of full pulpotomy in mature permanent molars with irreversible pulpitis.
- Trial name
- NCT06597487
- Testing
- Full pulpotomy, Conventional root canal treatment
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Misr International University
Molar-Incisor Hypomineralization (MIH)
Total Pulpotomy With Two Repair Cements in Hypomineralized Teeth
BRIEF SUMMARY The goal of this clinical trial is to learn whether two materials used during pulpotomy treatment can reduce pain after treatment in children with molar-incisor hypomineralization (MIH), deep tooth decay, and…
- Trial name
- DOR-PULP (NCT07774806)
- Testing
- MTA group, CIMMO DTA® group
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Meire Coelho Ferreira
Irreversible Pulpitis
Effect of Sufentanil on the Rate of Anesthesia
The aim of this study was to compare the effects of Lidocaine/epinephrine with and without Sufentanil on the rate of anesthesia after supplemental intraligamentary injection (PDL) in teeth with irreversible pulpitis.
- Trial name
- NCT01572116
- Testing
- Lidocaine with Epinephrine+ Normal saline, Lidocaine with Epinephrine + sufentanil
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Pulpitis - Irreversible
Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Inflammed Pulp
Group I (Experimental group I): Lesion Sterilization and Tissue Repair with radicular instrumentation. Coronal and accessible radicular pulp tissue are extirpated using rotary files.
- Trial name
- NCT05336682
- Testing
- Lesion Sterilization and Tissue Repair with radicular instrumentation, Lesion Sterilization and Tissue Repair without radicular instrumentation, Conventional pulpectomy
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis, Pulpitis - Irreversible
Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples
This study aimed to compare the changes in AQP -4, -5, -9, and IL-8 levels in pulp tissue, GCF, and dentin fluid samples routinely obtained during the treatment of healthy and symptomatic teeth diagnosed with irreversible…
- Conditions
- Pulpitis, Pulpitis - Irreversible, Pulp Inflammation, Healthy Pulp
- Trial name
- NCT06938191
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Symptomatic Irreversible Pulpitis
Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness
This clinical study investigates whether the combination of ibuprofen and serratiopeptidase as oral premedication can enhance the effectiveness of the inferior alveolar nerve block (IANB) in patients with symptomatic irreversible…
- Trial name
- NCT07146997
- Testing
- Patients will receive ibuprofen (400-600 mg, standard therapeutic dose) orally, 1 hour prior to IANB, Group III - Serratiopeptidase Group, Group IV - Combination Group (Ibuprofen and Serratiopeptidase)
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Zahoor khan
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy vs. Pulpectomy in Vital Primary Molars With Symptomatic Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06183203
- Testing
- Pulpotomy, Pulpectomy
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nebu Philip
Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis
Concerned Growth Factor VS Miniral Trioide Aggregate in Treatment of Mature Permanent Teeth of Children With Symptomatic Irreversible Pulpitis.
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
- Trial name
- NCT07138287
- Testing
- Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis, Apical Periodontitis
Bite Force Measurements
ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids.
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Pulpal Necrosis
- Trial name
- NCT06843525
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Rutgers, The State University of New Jersey
Dental Caries Extending to Pulp, Pulp Disease, Dental
The Effect of Different Risk Factors on the Success Rate of VPT
This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure.
- Conditions
- Dental Caries Extending to Pulp, Pulp Disease, Dental, Irreversible Pulpitis, Reversible Pulpitis
- Trial name
- NCT06844448
- Testing
- with Biodentine, with MTA
- Where
- Hungary
- Volunteers
- 400 people
- Sponsor
- Semmelweis University
Effect of Drug
Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
This study aims to compare the pain reduction efficacy of Trypsin-Chymotrypsin and Naproxen sodium after root canal treatment in patients with symptomatic irreversible pulpitis.
- Trial name
- NCT06562816
- Testing
- Trypsin-Chymotrypsin, Naproxen Sodium 550mg
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis
Effect of preoperative oral Ibuprofen on anesthetic efficacy of inferior alveolar nerve block with supplemental buccal and lingual infiltrations using articaine in mandibular molar teeth with irreversible pulpitis.
- Trial name
- NCT05927922
- Testing
- Oral Ibuprofen (Abbott, Egypt)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Canal Infection
Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis
Achieving profound anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis is still a demanding clinical challenge.
- Trial name
- NCT04929522
- Testing
- local anesthesia
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Symptomatic Irreversible Pulpitis, Acute Apical Periodontitis of Pulpal Origin
The Effect of Central Sensitization on Assessment Capacity of Patients
the aim of this study is to evaluate the effect of dental hyperalgesia and mechanical allodynia on the assessment capacity of individuals in a local Turkish population.
- Trial name
- NCT03553641
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Dental Caries, Irreversible Pulpitis
Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis
This study evaluates the effectiveness of photobiomodulation (PBM) in conjunction with mineral trioxide aggregate (MTA) pulpotomy for treating irreversible pulpitis in immature first permanent molars.
- Trial name
- NCT06730360
- Testing
- MTA Pulpotomy without photobiomodulation, MTA Pulpotomy with Photobiomodulation (LLLT)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Pulpitis, Pulp Inflammation
Comparison of IL-8, FGF-1 and VEGF Levels in Pulpal Tissue, GCF and Dentinal Fluid Samples of Healthy, Reversible and Irreversible Pulpitis Diagnosed Teeth
This study will include 51 patients diagnosed with healthy, reversible and irreversible pulpitis. IL-8, FGF-1 and VEGF levels will be compared using pulpal tissue, gingival crevicular fluid, dentinal fluid samples collected from…
- Conditions
- Pulpitis, Pulp Inflammation, Healthy Pulp, Biomarkers
- Trial name
- NCT06936553
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Pulpitis - Irreversible
Outcome Following Endodontic Treatment Using Traditional Access Versus Conservative Access
This study will compare the outcome of endodontic treatment using conservative or traditional access design in permanent molars with clinical signs indicative of irreversible pulpitis
- Trial name
- NCT05402098
- Testing
- Endodontic treatment using traditional access, Endodontic treatment using conservative access
- Where
- India
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak