Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible PulpitisNCT07138287
Concerned Growth Factor VS Miniral Trioide Aggregate in Treatment of Mature Permanent Teeth of Children With Symptomatic Irreversible Pulpitis.
A study testing Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis in people with Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis, run by Minia University at 1 site in Egypt.
Trial summary
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis Read more about this study
- Who is it for?
- Ages 9 to 16 yearsHealthy volunteers can take part
- Conditions the study is for
- Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis
- What is being tested?
- Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 siteEgypt
- Study dates
- 11 Jul 2025to 1 Sep 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 9 to 16 years
- All sexes
- Healthy volunteers accepted
- Child
Who may be able to join
None listed.
Who cannot join
- medically compromised children.
- non restorable tooth
- Necrotic tooth
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Minya University Faculty of Dentistry
Minya
Elheeny, Associate Professor, 201064257135, Ahmedelheeny@gmail.com
About this study
Official title: Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar of Children With Irreversible Pulpitis. An 18-month Randomized Control Trial
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
- Being tested
- Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitisProcedure or surgery
Also called Pulpotomy
Concerned Growth factor in management of Mature permanent Molar of children with irreversible pulpitis
| Study group | Role | What they receive |
|---|---|---|
| Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis | Experimental | Not described Receives: Procedure: Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis |
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinical evaluation of cases using visual analogue scale, electrical pulp testing, Sensibility testing using both hot and cold and Percussion test for the teeth
Pain assessment using visual analogue scale pre operative, 6 hours post operative, 12hours post operative, 1 day post operative, 2 days post operative, 4 days, 1week, 2 weeks, 1month, 3 months, 6months and 1 year Sensibility test using thermal both hot and cold will be done pre operative and post operative Electrical pulp testing pre operative and post operative follow ups Percussion test to define any periapical or Periodontal issues
Measured: 12 months
Radiographic evaluation of sucess of concentrated Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar with irreversible pulpitis
Standerdized periapical x rax will be performed before treatment, 3 months, 6minths, 9 months and one year after pulpotomy in the treated teeth to evaluated radiographic sucess
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Aug 2025
- Study start11 Jul 2025
- Primary completion1 Oct 2025 (estimated)
- Study completion1 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible PulpitisStudies of the same condition, open and under way.
- More trials run by Minia UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
- Masking
- None (open label)
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Minia University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmad Elheeny, Minia University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07138287
- Sponsor's protocol ID
- 3082
- Status last verified
- Aug 2025
- First submitted
- 10 Jul 2025
- Last updated
- 22 Aug 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: We intend to share the data in BMC. We will share study protocol, materials and methods, results, discussion, recommendations and limitations of the current study
Study at a glance
From the registry record, last updated by the sponsor on 22 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar of Children With Irreversible Pulpitis. An 18-month Randomized Control Trial
- ClinicalTrials.gov ID
- NCT07138287
- Acronym / sponsor ID
- 3082
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Minia UniversityUniversity, hospital or other
- Study start
- 11 Jul 2025 (actual)
- Primary completion
- 1 Oct 2025 (estimated)
- Study completion
- 1 Sep 2026 (estimated)
- First posted
- 22 Aug 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
| Arm | Type | Receives |
|---|---|---|
| Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis | Experimental | Procedure: Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis |
Who may qualify
- Ages
- 9 to 16 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
Key inclusion criteria (0 listed)
Key exclusion criteria (3 listed)
- medically compromised children.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitisAlso: PulpotomyConcerned Growth factor in management of Mature permanent Molar of children with irreversible pulpitis | Procedure or surgery | Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis |
Primary outcome
Clinical evaluation of cases using visual analogue scale, electrical pulp testing, Sensibility testing using both hot and cold and Percussion test for the teeth
Time frame: 12 months
Pain assessment using visual analogue scale pre operative, 6 hours post operative, 12hours post operative, 1 day post operative, 2 days post operative, 4 days, 1week, 2 weeks, 1month, 3 months, 6months and 1 year Sensibility test using thermal both hot and cold will be done pre operative and post operative Electrical pulp testing pre operative and post operative follow ups Percussion test to define any periapical or Periodontal issues
Radiographic evaluation of sucess of concentrated Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar with irreversible pulpitis
Time frame: 12 months
Standerdized periapical x rax will be performed before treatment, 3 months, 6minths, 9 months and one year after pulpotomy in the treated teeth to evaluated radiographic sucess
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Aug 2025.
- Individual participant dataSharing planned: Yes. We intend to share the data in BMC. We will share study protocol, materials and methods, results, discussion, recommendations and limitations of the current study
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis in people with Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis, run by Minia University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 22 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mahmoud Mostafa Abdelhakim, Master degree (201004445513, mahmoudmostafa100001@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinical evaluation of cases using visual analogue scale, electrical pulp testing, Sensibility testing using both hot and cold and Percussion test for the teeth (time frame: 12 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Aug 2025.