Clinical trials: Pulpitis - Irreversible
Post Operative Endodontic Pain
Reduction of Post-operative Endodontic Pain
To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.
- Trial name
- NCT01480752
- Testing
- Lornoxicam, normal saline, no injection
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Symptomatic Irreversible Pulpitis (SIP)
Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment
This randomized control trial will be planned according to PRIRATE 2020 guideline for reporting randomized trials in Endodontics.
- Trial name
- NCT07759349
- Testing
- Acetaminophen, NSAID, trypsin-chymotrypsin
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Irreversible Pulpitis
Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis
To compare the effect of different VPT methods using Calcium Enriched Mixture (CEM) cement for management of human dental pulp with irreversible pulpitis.
- Trial name
- NCT01561183
- Testing
- Indirect pulp capping (IPC), Direct pulp capping (DPC), Miniature pulpotomy (MP)
- Where
- Iran
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Symptomatic Irreversible Pulpitis
Vital Pulp Therapy Versus Root Canal Treatment for Irreversible Pulpitis With Incipient Apical Periodontitis Diagnosed Using Artificial Intelligence This Keeps: the Main Intervention (Vital Pulp Therapy) the Comparison (Root Canal Treatment) the Condition (Irreversible Pulpitis With Incipient Apic
This study evaluates postoperative pain and treatment outcomes following vital pulp therapy and root canal treatment in patients with symptomatic teeth.
- Trial name
- NCT07549620
- Testing
- Vital Pulp Therapy, Root Canal Treatment
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Ain Shams University
Pulpitis - Irreversible
Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain
The purpose of this study is to assess the effect of preoperative a single-dose of 50 mg diclofenac potassium on postoperative endodontic pain in mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT03341260
- Testing
- Diclofenac Potassium 50mg Tab.
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Pulpitis - Irreversible
Comparative Evaluation of Partial and Complete Pulpotomy in Permanent Molars
This study will compare the outcome of partial pulpotomy and complete pulpotomy in mature permanent molars with clinical signs indicative of irreversible pulpitis
- Trial name
- NCT04397315
- Testing
- Pulpotomy to the level of canal orifices, Pulpotomy up to superficial 2-3 mm of pulp chamber
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pain
Comparative Evaluation of Post Obturation Pain After Root Canal Treatment Using Tricalcium Silicate vs Resin-Based Sealers
This is a randomized controlled trial comparing the mean and standard deviation of postobturation pain using two different sealers: a tricalcium silicate-based sealer (CeraSeal) and a resin-based sealer (Endoplus) in patients…
- Trial name
- NCT07388368
- Testing
- Tricalcium silicate sealar, Resin based sealer
- Where
- Pakistan
- Volunteers
- 118 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Irreversible Pulpitis, Deep Caries
TheraCal LC Coronal Pulpotomy and MTA Coronal Pulpotomy in Mature Permanent Molars
To evaluate and compare the clinical and radiographic success rate of TheraCal LC and MTA for coronal pulpotomy of mature permanent molar in 9-14 year children.
- Trial name
- NCT05733468
- Testing
- Theracal LC, MTA
- Where
- India
- Volunteers
- 72 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis
Comparison Between Reciproc and Oneshape Systems
A randomized clinical trial to assess postoperative pain in patients with symptomatic irreversible pulpitis after using Reciproc versus One Shape rotary NiTi Systems.
- Trial name
- NCT02940782
- Testing
- Reciproc single file system, One Shape single file system, X-smart Plus, Dentsply Maillefer, Ballaigues, Switzerland
- Volunteers
- 54 people
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Postoperative Pain Intensity After Pulpotomy
Introduction: This study aimed to compare postoperative pain rates following sodium hypochlorite (NaOCl) and KTP laser-assisted pulpotomy treatments in permanent teeth with deep caries, and symptomatic irreversible pulpitis.
- Trial name
- NCT05424796
- Testing
- Physiological saline, Hemostasis and cavity disinfection with NaOCl, Hemostasis and cavity disinfection with KTP laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Symptomatic Irreversible Pulpitis
Efficacy of Pulpal Anesthesia and Patient Preference Using the Needle-less and Conventional Injection Techniques
Pain despite being a physiological experience, is considerably affected by the emotional states, such as anxiety and fear. It was demonstrated that individuals with a high level of anxiety experience difficult anesthesia and more…
- Trial name
- NCT05724862
- Testing
- Needle-less jet anaesthesia, Conventional Injection Anesthesia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain, Acute, Irreversible Pulpitis
To Evaluate Post Operative Pain Using Two Different Kind of Sealers in Obturation of Teeth With Symptomatic Irreversible Pulpitis During Second Visit When the Patient is Painless
The goal of this randomized clinical trial is to evaluate pain after root canal treatment using two different kinds of sealers during obturation in 60 healthy , male and female patients ages between 18 to 40 years.
- Trial name
- NCT07266974
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jaweria Gul Keyani
Pain, Postoperative
Ibuprofen Versus Ibuprofen/Acetaminophen Postoperatively in Patients Needing Root Canal Therapy
Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting.
- Trial name
- NCT03631433
- Testing
- Ibuprofen 600 mg, ibuprofen 600 mg and acetaminophen 650 mg
- Volunteers
- 102 people
- Sponsor
- Ohio State University
Symptomatic Irreversible Pulpitis
The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve Block
Articaine/epinephrine and lidocaine/epinephrine are the most common routine local anesthetic agents currently used in dentistry.
- Trial name
- NCT04186299
- Testing
- Clonidine, Articaine Hydrochloride + Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain, Postoperative, Irreversible Pulpitis
Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain
Intracanal medicaments have been frequently used in patients with endodontic and periradicular infection for the elimination of microorganisms.
- Trial name
- NCT04900571
- Testing
- Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Symptomatic Irreversible Pulpitis
Effect of Cryotherapy Versus Post-operative Ibuprofen Medication on Post-operative Pain in Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Evaluation of the effect of cryotherapy versus post-operative ibuprofen medication on post-operative pain in mandibular molar teeth with symptomatic irreversible pulpitis .
- Trial name
- NCT05341999
- Testing
- cold saline (cryotherapy), Ibuprofen 400 mg, Final irrigation with normal saline
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy
The efficacy of short course orally administered dexamethasone on the reduction of pain before conventional pulpotomy has not yet been demonstrated.
- Trial name
- NCT05761730
- Testing
- Dexamethasone Oral
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- May Samaha
Post-endodontic Pain
Comparison Of The Effect Of Final Rinse Of Tramadol and Dexamethasone on Post-Endodontic Pain in Teeth With SIP
Briefly, 105 teeth with symptomatic irreversible pulpitis will be included in the study and randomly allocated to three groups (A, B and C).
- Trial name
- NCT07036237
- Testing
- Tramadol group, Dexamethasone Group
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Endodontic Disease, Post Operative Pain
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
This study will assess the efficacy of two local anesthetics (2% lidocaine 1:100,000 epinephrine and 0.5% bupivicaine 1:200,000 epinephrine) in reducing post-operative pain in patients receiving endodontic treatment.
- Conditions
- Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis
- Trial name
- NCT05338671
- Testing
- Local anesthetic
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pulpitis - Irreversible
Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis
This study will compare the outcome of partial and miniature pulpotomy in mature permanent molars with symptomatic partial irreversible pulpitis
- Trial name
- NCT05406557
- Testing
- Partial pulpotomy, Miniature pulpotomy
- Where
- India
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak