Clinical trials: Pulmonary Embolism, completed
Deep Vein Thrombosis, Pulmonary Embolism
D-dimer Levels During and After Anticoagulation in Patients With a Previous Venous Thromboembolism: Effects on the Risk of Recurrence
The results of the Prolong study, currently submitted for publication, show that patients with a first unprovoked venous thromboembolic event who have altered D-dimer levels, measured one month after anticoagulation with vitamin…
- Trial name
- NCT00266045
- Where
- Italy
- Volunteers
- 355 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pulmonary Embolism
First - In - Man Study to Assess the Safety and Feasibility of The Bashir™ Endovascular Catheter for the Treatment of Acute Pulmonary Embolism
The Bashir™ Endovascular Catheter is a device intended for the localized infusion of therapeutic agents into the pulmonary artery and peripheral vasculature.
- Trial name
- NCT03927508
- Testing
- r-tPA, The Bashir™ Endovascular Catheter
- Where
- 5 sites in United States
- Volunteers
- 9 people
- Sponsor
- Thrombolex, Inc.
Pulmonary Thromboembolisms, Pulmonary Embolism
Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events
Deep vein thrombosis (DVT) occurs when a blood clot forms in a deep vein, typically in the lower extremities. Pulmonary embolism (PE) occurs when a DVT clot (or fragment) breaks free and travels through the heart to the pulmonary…
- Trial name
- NCT03183063
- Testing
- 4DCT and SPECT/CT, 4DCT with BiPAP and SPECT/CT, 4DCT with CTA in suspected PE
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Thomas Guerrero
Pulmonary Embolism
Angiojet Rheolytic Thrombectomy in Case of Massive Pulmonary Embolism
This pilot study is mainly aimed to evaluate the feasibility and safety of the percutaneous Angiojet Rheolytic Thrombectomy (ART) in patients presenting a MPE.
- Trial name
- ART-MPE (NCT00780767)
- Testing
- ANGIOJET RHEOLYTIC THROMBECTOMY
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- University Hospital, Geneva
Venous Thromboembolism
Predicting Bleeding Risk on Anticoagulant Therapy for Venous Thromboembolism
The main objective of the study is to develop or validate a clinical prediction rule for major bleeding in patients on oral anticoagulant therapy who have been safely anticoagulated without bleeding or venous thromboembolism…
- Trial name
- NCT00788736
- Where
- 12 sites in United States, Canada and 1 more
- Volunteers
- 2,537 people
- Sponsor
- Ottawa Hospital Research Institute
Pulmonary Embolism
Short-term Clinical Deterioration After Acute Pulmonary Embolism
This is a prospective, observational, multicenter cohort study to compare right ventricular dysfunction dependent and independent prognostic models for short-term serous adverse events in patients who are diagnosed with pulmonary…
- Trial name
- NCT03915925
- Where
- 6 sites in United States
- Volunteers
- 935 people
- Sponsor
- Wake Forest University Health Sciences
Cutaneous Manifestations, Skin Manifestations
Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019.
- Conditions
- Cutaneous Manifestations, Skin Manifestations, COVID-19, COVID-19 Pneumonia
- Trial name
- NCT05094687
- Where
- Pakistan
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Acute Pulmonary Embolism
A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism
This trial is being conducted to assess the efficacy and safety of recombinant Human Prourokinase in the acute pulmonary embolism.
- Trial name
- ERUPTE (NCT03108833)
- Testing
- Recombinant Human Prourokinase, Alteplase
- Where
- 18 sites in China
- Volunteers
- 108 people
- Sponsor
- Tasly Biopharmaceuticals Co., Ltd.
COVID, Thrombosis
Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19
Worldwide observational studies indicate a significant prothrombogenic effect associated with SARS-CoV-2 infection with a high incidence of venous thromboembolism (VTE), notably life-threatening pulmonary embolism.
- Conditions
- COVID, Thrombosis, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- COVI-DOSE (NCT04373707)
- Testing
- Enoxaparin
- Where
- 17 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Central Hospital, Nancy, France
Venous Thromboembolism
RE-COVERY DVT/PE: Global Study on Treatment Secondary Prevention of Acute Venous Thromboembolism
RE-COVERY is a large, multi-national, multi-center observational study based on new data collection. The study will enroll and characterize patients within 30 days of being diagnosed with an acute DVT and/or PE.
- Trial name
- NCT02596230
- Where
- 222 sites in United States, Argentina and 35 more
- Volunteers
- 7,797 people
- Sponsor
- Boehringer Ingelheim
Pancreas Cancer, DVT
Pharmacokinetics of Apixaban in Patients Undergoing Pancreaticoduodenectomy
Study investigators will examine the absorption characteristics of apixaban, a direct-acting oral anticoagulation, in patients who have underwent a particular kind of surgery (pancreaticoduodenectomy) which involves resection of…
- Conditions
- Pancreas Cancer, DVT, Pulmonary Embolism
- Trial name
- PAP-UP (NCT04191928)
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Thomas Jefferson University
Anti-Xa Assay in Pulmonary Embolism
Anti-Xa Assay Correlation to the Efficacy and Safety of Enoxaparin in the Treatment of Pulmonary Embolism
The aim of the present study is to monitor anticoagulant therapy by anti-Xa assay and correlate its level to the efficacy and safety of enoxaparin in the treatment of pulmonary embolism.
- Trial name
- NCT02977013
- Testing
- Anti-Xa assay
- Volunteers
- 42 people
- Sponsor
- Mohamed Sayed Mohamed Abbas
Massive Pulmonary Embolism
Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE
Objective: to evaluate the efficacy and safety of the Recombinant Non-immunogenic Staphylokinase with its single bolus administration in comparison with the bolus-infusion administration of the Alteplase in patients with massive…
- Trial name
- NCT04688320
- Testing
- Recombinant nonimmunogenic staphylokinase, Alteplase
- Where
- 23 sites in Russia
- Volunteers
- 310 people
- Sponsor
- Supergene, LLC
Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
- Trial name
- NCT07356908
- Testing
- polysomnography
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Cancer, Deep Venous Thrombosis
Cohort Study to Identify Cancer Patients at High Risk of Venous Thromboembolism
Cancer patients are at increased risk of deep venous thrombosis and pulmonary embolism, collectively termed venous thromboembolism (VTE).
- Conditions
- Cancer, Deep Venous Thrombosis, Pulmonary Embolism
- Trial name
- MICA (NCT02095925)
- Where
- 7 sites in France, Italy and 2 more
- Volunteers
- 900 people
- Sponsor
- Harry R. Buller
Pneumonia, Viral
Assessment of the Risk of Pulmonary Embolism and Coagulation Profile in Patients With COVID-19 Lung Disease
The current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is complicated by pneumonia (15 to 20% of cases) requiring hospitalization with oxygen therapy.
- Trial name
- COVIDEP (NCT04479540)
- Testing
- Angiography scanner
- Where
- France
- Volunteers
- 117 people
- Sponsor
- Hopital Foch
COVID-19
Role of Microparticles in Covid-19 Infection
Among the distinctive features of Covid-19, numerous reports have stressed the importance of vascular damages associated with coagulopathy onset.
- Trial name
- MICO (NCT04448743)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Pulmonary Embolism
Prognostic Value of Computed Tomography (CT) Scan in Hemodynamically Stable Patients With Acute Symptomatic Pulmonary Embolism
The objectives of the PROTECT study are: To assess the role of CT pulmonary angiography in the risk stratification of hemodynamically stable patients with acute symptomatic pulmonary embolism (PE).
- Trial name
- PROTECT (NCT00880737)
- Where
- Spain
- Volunteers
- 850 people
- Sponsor
- Carlos III Health Institute
Rheumatic Disease, Neoplasms
Latest Imaging SPECT System Evaluation Phase 1
Monocentric study for the evaluation of a whole body CZT scintigraphy system.
- Conditions
- Rheumatic Disease, Neoplasms, Parathyroid Diseases, Pulmonary Embolism
- Trial name
- LISSE1 (NCT04704349)
- Testing
- Scintigraphy
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Pulmonary Embolism
Endovascular Engineering ENGULF Study
Evaluation of initial safety and clinical feasibility of the Hēlo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).
- Trial name
- ENGULF (NCT05597891)
- Testing
- Hēlo PE Thombectomy System
- Where
- 21 sites in United States
- Volunteers
- 177 people
- Sponsor
- Endovascular Engineering