Pulmonary EmbolismNCT07356908
Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism
An observational study of Pulmonary Embolism and Sleep Apnea Syndrome (OSAS), run by Alexandria University at 1 site in Egypt.
Trial summary
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
- What is being tested?
- polysomnography
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2025to 1 Jan 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: adult patients more than 18 years diagnosed with pulmonary embolism managed and followed up at the chest diseases department
Who may be able to join
- Age≥18years.
- Objectively confirmed acute pulmonary embolism by computed tomography pulmonary angiography (CTPA).
- Hemodynamically stable or clinically stabilized within 72 hours of admission. .Ability to provide informed consent.
Who cannot join
- .Known central sleep apnea without obstructive features. .Inabilityto undergo sleep study evaluation.
- Pregnancy
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Short- Term Outcome and One -Year Recurrence in Acute Pulmonary Embolism Patients With and Without Sleep - Disordered Breathing
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
Read the detailed description
This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CT pulmonary angiography and followed up with sllep study to asses the effect of sleep related breathing disorderon the recurrence of emboli.
- Conditions
- Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
- Being tested
- polysomnography
- Keywords
- pulmonary embolism, sleep apnea
- Medical subject headings
- Pulmonary Embolism, Sleep Apnea Syndromes, Sleep Apnea, Obstructive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
polysomnographyDiagnostic test
This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CTPA
What is being measured
The primary outcome is the main question the study is designed to answer.
Pulmonary embolism recurrence
ocuurence of pulmonary embolism during the follow up period confirmed by CTPA
Measured: 12 months
Recurrence of Pulmonary Embolism
occurence of objectively confirmed pulmonary embolism during the one t=year follow up period confirmed by CTPA
Measured: ONE YEAR
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Jan 2026
- Study start1 Jan 2025
- Primary completion1 Jan 2026
- Study completion1 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pulmonary EmbolismStudies of the same condition, open and under way.
- More trials run by Alexandria UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Alexandria University
- Sponsor type
- University, hospital or other
- Collaborators
- University of Alexandria
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07356908
- Sponsor's protocol ID
- fac med
- Other IDs
- faculty of medicin
- Status last verified
- Jan 2025
- First submitted
- 13 Jan 2026
- Last updated
- 21 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: refusal by the department
Study at a glance
From the registry record, last updated by the sponsor on 21 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Short- Term Outcome and One -Year Recurrence in Acute Pulmonary Embolism Patients With and Without Sleep - Disordered Breathing
- ClinicalTrials.gov ID
- NCT07356908
- Acronym / sponsor ID
- fac med
- Conditions
- Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
- Keywords
- pulmonary embolism, sleep apnea
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Alexandria UniversityUniversity, hospital or other
- Collaborators
- University of Alexandria
- Study start
- 1 Jan 2025 (actual)
- Primary completion
- 1 Jan 2026 (actual)
- Study completion
- 1 Jan 2026 (actual)
- First posted
- 21 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
Detailed description
This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CT pulmonary angiography and followed up with sllep study to asses the effect of sleep related breathing disorderon the recurrence of emboli.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- adult patients more than 18 years diagnosed with pulmonary embolism managed and followed up at the chest diseases department
Key inclusion criteria (3 listed)
- Age≥18years.
Key exclusion criteria (2 listed)
- .Known central sleep apnea without obstructive features. .Inabilityto undergo sleep study evaluation.
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| polysomnographyThis prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CTPA | Diagnostic test | – |
Primary outcome
Pulmonary embolism recurrence
Time frame: 12 months
ocuurence of pulmonary embolism during the follow up period confirmed by CTPA
Recurrence of Pulmonary Embolism
Time frame: ONE YEAR
occurence of objectively confirmed pulmonary embolism during the one t=year follow up period confirmed by CTPA
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jan 2026.
- Alonso-Fernández A, de la Peña M, Romero D, Piérola J, Carrera M, Barceló A, Soriano JB, García Suquia A, Fernández-Capitán C, Lorenzo A, García-Río F. Association between obstructive sleep apnea and pulmonary embolism. Mayo Clin Proc. 2013 Jun;88(6):579Link provided by the sponsor.
- Individual participant dataSharing planned: No. refusal by the department
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Pulmonary Embolism and Sleep Apnea Syndrome (OSAS), run by Alexandria University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pulmonary embolism recurrence (time frame: 12 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jan 2026.