Clinical trials: Pterygium
Polycystic Liver Disease, Hepatomegaly
Open-Label Extension of LOCKCYST Trial
Positive data originating from two polycystic liver patients treated with somatostatin analogues, showed a volume reduction of 38.3% and 14.9%.
- Conditions
- Polycystic Liver Disease, Hepatomegaly, Liver Diseases, Polycystic Kidney
- Trial name
- LOCKCYST-ext (NCT00771888)
- Testing
- lanreotide
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 54 people
- Sponsor
- Radboud University Medical Center
Pterygium of Conjunctiva and Cornea
Outpatient Performed Pterygium Surgery Study
This is a randomized controlled trial of postoperative bevacizumab or 5-fluorouracil subconjunctival injections vs placebo for the recurrence of pterygia after excision using conjunctival autograft.
- Trial name
- OPPS (NCT03037736)
- Testing
- 5-Fluorouracil, Bevacizumab, Normal saline
- Sponsor
- University of California, San Francisco
Pterygium of the Conjunctiva and Cornea
Conjunctival Transpositional Surgery for Primary Pterygium
This prospective single-arm interventional study evaluates the recurrence rate and functional outcomes following conjunctival transpositional pterygium surgery without bare sclera formation.
- Trial name
- NCT07343011
- Testing
- Conjunctival Transpositional Pterygium Surgery
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Zahedan University of Medical Sciences
Pterygium
Prospective Randomized Pilot Study Comparing Inferior Versus Superior Conjunctival Autografts for Primary Pterygia
The purpose of this study is to determine if there is any difference in the surgical time when the surgery is performed with a graft taken from under the upper lid versus lower lid.
- Trial name
- NCT01261455
- Testing
- Location of the autograft taken following pterygium excision
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Pterygium
Comparing Two Surgical Methods to Prevent Pterygium Regrowth
This study compares two surgical techniques for preventing the regrowth of a pterygium, a non-cancerous growth on the eye. After surgically removing the pterygium, surgeons will cover the area with either a flap of nearby tissue…
- Trial name
- NCT07277426
- Testing
- Conjunctival Rotational Flap, Conjunctival Autograft
- Volunteers
- 342 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Glaucomas, Pterygium
Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital
The purpose of this study is to determine whether the ologen (OculusGen) Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery and pterygium excision surgery.
- Trial name
- NCT00478790
- Testing
- ologen™ Collagen matrix implantation in glaucoma filtering surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Pro Top & Mediking Company Limited
Pterygium
Corneal Topographic Changes After Pterygium Surgery
The purpose of the study is to assess the corneal topographic changes after primary pterygium surgery
- Trial name
- NCT05026307
- Testing
- Excision of pterygium
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Pterygium
Dextenza in Pterygium Surgery
DEXTENZA for the treatment of post-surgical pain and inflammation compared to standard of care topical prednisolone acetate 1% in patients who undergo pterygium surgery (excision of pterygium with conjunctival autograft)
- Trial name
- NCT04403516
- Testing
- Dexamethasone Intracanalicular Insert, 0.4mg, Prednisolone Acetate 1%
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michelle Rhee MD
Pterygium
A Study of the Response to AG-86893 in Patients With Pterygium Hyperemia
A pterygium is a wing-shaped, benign tissue growth which forms on the surface of the conjunctiva and grows towards the cornea. It can eventually lead to vision impairment.
- Trial name
- SURPH (NCT03533244)
- Testing
- 0.1% AG-86893 Eye Drops, 0.3% AG-86893 Eye Drops, Vehicle Eye Drops
- Where
- 6 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Allgenesis Biotherapeutics Inc.
Pterygium
Pterygium Treatment Using Single Beta-therapy as Adjuvant Treatment Compared to Conjunctival Autograft
PURPOSE: To affirm the effectiveness and complication rate of postoperative single-dose beta-irradiation (RT) with (90) Sr in the case of primary pterygium in a clinical trial.
- Trial name
- NCT01024257
- Testing
- beta-irradiation, conjunctival autograft
- Where
- Brazil
- Sponsor
- Marilia Medicine School
Pterygium
Treatment of Primary Type I Pterygia With Argon Laser
Introduction: Pterygium is a wing shape degenerative and hyperplastic growth of the bulbar conjunctiva extending onto the cornea, most commonly on the nasal side. Management of pterygium can be medical, surgical or combined.
- Trial name
- NCT03485001
- Testing
- Argon Laser Treatment
- Where
- Mexico
- Volunteers
- 16 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Pterygium
Assessment of Low-temperature Plasma Surgery System in Pterygium With Fibrin Glue and Conjunctival Autografts
Pterygium is a wing-shaped fibrovascular tissue that has proliferated onto the cornea. Ultraviolet radiation and hot, dusty, windy, dry, smoky environments are regarded as risk factors for pterygium .
- Trial name
- NCT03204084
- Testing
- Low-temperature Plasma Surgery System
- Volunteers
- 56 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pterygium
Role of Sub-Conjunctival Bevacizumab in Post Pterygium Excision Management
A pterygium is a fibrovascular growth originating from the conjunctiva that grows onto the surface of the cornea. Frequently, these pterygia will recur even after surgical resection.
- Trial name
- NCT01736449
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Arrowhead Regional Medical Center
Pterygium, Corneal Astigmatism
Comparison Of Keratometric Readings Pre and Post Pterygium Excision With Conjunctival Autograft Transplantation
Pterygium, often called "surfer's eye," is a common eye condition in which a raised, fleshy growth of tissue extends from the white part of the eye onto the clear cornea.
- Trial name
- NCT07198126
- Testing
- Pterygium Excision with Conjunctival Autograft
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Mughal Eye Trust Hospital
Pterygium
Comparison of Glue With Sutures for Pterygium Surgery
Pterygium excision surgery involves excising the abnormal growth from the cornea and filling the defect with a conjunctival (white of the eye) graft from the superior part of the eye.
- Trial name
- NCT00326560
- Testing
- Pterygium excision and conjunctival autograft
- Where
- New Zealand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wellington Hospital
Pterygium
ICG Angiography in Amniotic Membrane Graft and Conjunctival Autograft After Pterygium Excision
To evaluate graft vascularization and compare the vascularization patterns of conjunctival autografts with amniotic membrane grafts to better understand the factors involved in pterygium recurrence.
- Trial name
- NCT00383825
- Testing
- Anterior segment indocyanine green angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pterygium
Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision
To compare the efficacy of rotational narrow strip conjunctival graft to full conjunctival graft in primary pterygium excision. Risk analysis of factors that may affects the recurrence rate.
- Trial name
- NCT01083927
- Testing
- Rotational Narrow Strip Conjunctival Graft, Full Conjunctival Graft
- Where
- Malaysia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pterygium
Expression of CD44, PCNA and E-cadherin in Pterygium Tissue
Purpose: Pterygium is a common ocular surface disease defined by fibrovascular conjunctival growth extending onto the cornea. Its pathogenesis remains unclear.
- Trial name
- NCT06042296
- Testing
- Expression of CD44, E-cadherin and PCNA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Pterygium
Intraoperative Mitomycin C, Amniotic Membrane Transplantation and Conjunctival Autograft for Primary Pterygium
The purpose of this randomized multi-center clinical trial is to compare the efficacy and safety of intraoperative mitomycin C(MMC),amniotic membrane transplantation(AMT) and Conjunctival Autograft(CAG) for primary pterygium…
- Trial name
- NCT02102776
- Testing
- MMC, AMT, CAG
- Where
- 5 sites in China
- Volunteers
- 750 people
- Sponsor
- Sun Yat-sen University
Recurrent Pterygium, Conjunctival Scarring
Digital Colorimetric Scale for Recurrent Pterygium Scar Assessment
This observational study aims to evaluate and validate a digital colorimetric scale for the objective assessment of conjunctival scarring in patients with recurrent pterygium.
- Trial name
- DCS-PTER (NCT07458126)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana