Clinical trials: Pterygium
Percutaneous Pedicular Screw (PPS) Fixation, Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS TLIF) Surgeries
Comparison of Thoracolumbar Interfascial Plane Block (TLIP-block) and Local Anesthetic (LA) Infiltration in Minimally Invasive Spine Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effectiveness of the thoracolumbar interfascial plane block (TLIP block) versus local anesthetic (LA) infiltration in managing postoperative pain in minimally invasive surgery…
- Trial name
- NCT06761079
- Testing
- Thoracolumbar interfascial plane block, Local anesthetic infiltration
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Pterygium of Conjunctiva and Cornea, Pterygium of Both Eyes
Clinical Outcomes of Sutured Versus Sutureless Conjunctival Autograft in Primary Pterygium Excision
The goal of this study is to find out if a certain technique in pterygium excision surgery ,using no sutures, is better than the technique mostly used ,which uses sutures.
- Conditions
- Pterygium of Conjunctiva and Cornea, Pterygium of Both Eyes, Pterygium
- Trial name
- NCT06734663
- Testing
- Clinical outcomes of sutured versus sutureless conjunctival autograft in primary pterygium excision, pterygium excision and conjuctival graft suturing, pterygium excision and conjuctival graft placement by autologous blood
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Turner Syndrome, Pterygium Colli
Mehri Turki Webbed Neck Classification
This study aims to identify all types of congenital neck deformities called " webbed neck ". Through a literature survey, the researcher selected 27 articles describing the surgical treatment of the webbed neck, but without…
- Conditions
- Turner Syndrome, Pterygium Colli, Web Neck, Klippel-Feil Syndrome
- Trial name
- NCT06489392
- Where
- Tunisia
- Volunteers
- 78 people
- Sponsor
- Mohamed Tahar Maamouri University Hospital
Pterygium of Right Eye, Pterygium of Left Eye
Comparison of Recurrence Between Mini-SLET and Limbal-Conjunctival Autograft Techniques in Primary Pterygium
The surgical treatment options for pterygium, an abnormal growth on the eye's frontal surface can be treated with several surgical techniques.
- Conditions
- Pterygium of Right Eye, Pterygium of Left Eye, Pterygium of Both Eyes, Pterygium
- Trial name
- NCT06402643
- Testing
- Pterygium Excision
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Platelet-rich Fibrin, Macular Holes
Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases
The goal of this clinical trial is to observe the role of PRF in treating ophthalmic diseases.The efficacy and safety of PRF were validated for four ophthalmic conditions: macular hole, pterygium, corneal ulcer, and patients…
- Conditions
- Platelet-rich Fibrin, Macular Holes, Pterygium, Glaucoma
- Trial name
- NCT06200727
- Testing
- PRF membrane tamponade surgery in macular hole, ILM peeling in macular hole, PRF membrane grafting in pterygium
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Lei Du
Pterygium
Comparison Between Topical Mitomycin C and Cyclosporine
Pterygium is a disease associated with proliferation of the fibrovascular tissues of the conjunctiva into the cornea and is related to factors such as ultraviolet light exposure, chronic stimulation, inflammation, climate, and…
- Trial name
- NCT05627947
- Testing
- Mitomycin c
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Egymedicalpedia
Pterygium
Expression of CD44, PCNA and E-cadherin in Pterygium Tissue
Purpose: Pterygium is a common ocular surface disease defined by fibrovascular conjunctival growth extending onto the cornea. Its pathogenesis remains unclear.
- Trial name
- NCT06042296
- Testing
- Expression of CD44, E-cadherin and PCNA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Bethlem Myopathy, Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2
Global Registry for COL6-related Dystrophies
The Global Registry for COL6-related dystrophies (www.collagen6.org) is a database for individuals who have been diagnosed with Bethlem Myopathy, Ullrich Congenital Muscular Dystrophy (UCMD) or an intermediate form of these…
- Conditions
- Bethlem Myopathy, Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2, Ullrich Congenital Muscular Dystrophy 1, Autosomal Recessive, Ullrich Congenital Muscular Dystrophy 1, Autosomal Dominant
- Trial name
- NCT04020159
- Testing
- Patient Registry
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Pterygium of Conjunctiva and Cornea
Cauterization Versus fibrin Glue for Conjunctival Autografting in Primary Pterygium Surgery
Pterygium is a noncancerous growth of the conjunctival tissue over the cornea. It is a progressive disease that may lead to visual impairment in advanced stages, as well as restriction of ocular motility, chronic inflammation and…
- Trial name
- NCT03321201
- Testing
- Cauterization, Fibrin glue
- Where
- Croatia
- Volunteers
- 164 people
- Sponsor
- University of Split, School of Medicine
Autosomal Dominant Retinitis Pigmentosa, Eye Diseases
A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene
This study evaluates the safety, tolerability and efficacy of QR-1123 injection in the eye (intravitreal; IVT) injections (one eye/unilateral) in subjects receiving a single dose or repeat doses.
- Conditions
- Autosomal Dominant Retinitis Pigmentosa, Eye Diseases, Eye Diseases, Hereditary, Retinal Dystrophies
- Trial name
- AURORA (NCT04123626)
- Testing
- QR-1123
- Where
- 5 sites in United States
- Volunteers
- 11 people
- Sponsor
- ProQR Therapeutics
Recurrent Pterygium, Micro-Conjunctival Autografting Combined With Amniotic Membrane Transplantation
Micro-Conjunctival Autografting Combined With Amniotic Membrane Transplantation Treating Recurrent Pterygium Trial
To observe the effect of micro-conjunctival autografting combined with amniotic membrane transplantation on the postoperative recurrence, complications and ocular surface symptoms among patients with recurrent pterygium.
- Trial name
- NCT05362253
- Testing
- Micro-Conjunctival Autograft Combined with Amniotic Membrane Transplantation, Conventional Autologous Conjunctival Transplantation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Yifeng Yu
Pterygium
Dextenza in Pterygium Surgery
DEXTENZA for the treatment of post-surgical pain and inflammation compared to standard of care topical prednisolone acetate 1% in patients who undergo pterygium surgery (excision of pterygium with conjunctival autograft)
- Trial name
- NCT04403516
- Testing
- Dexamethasone Intracanalicular Insert, 0.4mg, Prednisolone Acetate 1%
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michelle Rhee MD
Pterygium
Preoperative Bevacizumab Injection in Primary Pterygium in Tunisian Patients
Purpose: To assess the efficacy and safety of a single preoperative intra-lesional bevacizumab injection in primary pterygium. Methods: The investigators conducted a randomized controlled interventional study from January 2019 to…
- Trial name
- NCT05314673
- Testing
- Preoperative Intra-lesional Bevacizumab Injection in primary pterygium, pterygium surgery without adjunctive therapy
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Hospital Fattouma Bourguiba
Pterygium
Efficacy of Autologous Fibrin Glue in Pterygium
Pterygium is wing-shaped, vascular, fleshy growth that originates on the conjuntiva and that can spread to the corneal limbus and beyond The surgical exeresis with autologous conjunctival autograft technique is the treatment of…
- Trial name
- NCT04151017
- Testing
- Autologous fibrin glue, Suture
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pterygium
Manifestations of Ocular Irritation Following Pterygium Excision With Sutures Fixed Conjunctival Autograft
In this work, the manifestations of ocular irritation associated with vicryl 8/0 sutures fixed conjunctival auto-graft in pterygium patients were evaluated.
- Trial name
- NCT05164900
- Testing
- pterygium excision with sutures fixed conjunctival auto-graft
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Tanta University
Pterygium
Corneal Topographic Changes After Pterygium Surgery
The purpose of the study is to assess the corneal topographic changes after primary pterygium surgery
- Trial name
- NCT05026307
- Testing
- Excision of pterygium
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Sohag University
Pterygium of Conjunctiva and Cornea
Outpatient Performed Pterygium Surgery Study
This is a randomized controlled trial of postoperative bevacizumab or 5-fluorouracil subconjunctival injections vs placebo for the recurrence of pterygia after excision using conjunctival autograft.
- Trial name
- OPPS (NCT03037736)
- Testing
- 5-Fluorouracil, Bevacizumab, Normal saline
- Sponsor
- University of California, San Francisco
Patients With Primary Nasal Pterygium
Effects of Ranibizumab in Primary Pterygium Surgery
Pterygium is a common ocular surface disease in Malaysia. Without treatment, it can lead to severe visual impairment. Recurrence is the commonest complication and novel treatment approaches are crucial to prevent vision loss.
- Trial name
- NCT04878835
- Testing
- intralesional ranibizumab
- Where
- Malaysia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Pterygium
Subconjunctival Injection of Triamcinolone Acetonide and Limited Peritomy During Pterygium Excision
Pterygium is characterized by encroachment of a fleshy fibrovascular tissue from the bulbar conjunctiva on to the cornea. Although previously thought to be a solely degenerative disease, a new evidence has demonstrated the role of…
- Trial name
- NCT03377348
- Testing
- intraoperative subconjunctival injection of triamcinolone acetonide and limited peritomy during bare scleral pterygium excision
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pterygium, Subconjunctival Hemorrhage
Brimonidine Tartrate for Pterygium Surgery
Pterygium excision and conjunctival autograft surgery is commonly done to treat pterygiums. Excessive bleeding during the procedure creates a challenging operating field, prolongs surgery time, and prolongs healing.
- Trial name
- NCT04683159
- Testing
- Brimonidine Tartrate 0.15% Oph Soln, Brimonidine Tartrate 0.025% Oph Soln
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists