Clinical trials: Psychotherapy
Treatment Resistant Depression, Major Depressive Disorder (MDD)
Behavioural Activation Therapy and Ketamine for Treatment-Resistant Depression
The goal of this clinical trial is to see if combining ketamine with behavioral activation (BA) therapy to treat moderate to severe treatment-resistant depression improves depressive symptoms and general functioning more than…
- Trial name
- NCT07801703
- Testing
- Ketamine (0.5 mg/kg), Behavioural Activation Therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- The Royal's Institute of Mental Health Research
Major Depressive Disorder
Mindfulness-Based Cognitive Therapy Effect on Depression and C-Reactive Protein Levels After 8 Weeks of Treatment
This study will investigate the efficacy of an 8-week course in Mindfulness-Based Cognitive Therapy (MBCT) for adults with major depressive disorder (MDD) by ;measuring change from baseline to completion of treatment at 8 weeks…
- Trial name
- NCT02385786
- Testing
- Mindfulness-Based Cognitive Therapy
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Suicide, Attempted, Suicidal Ideation
Brief Cognitive Behavioral Therapy Replication Trial
The overall goal for the proposed project is to test the effectiveness of BCBT for the prevention of suicide attempts in a sample of treatment-seeking U.S. military personnel and veterans.
- Trial name
- NCT03769259
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT), Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Lymphoma, Non-Hodgkin, Neoplasms
Meaning-Centered Psychotherapy in Advanced Cancer
We have developed an 8-week Meaning-Centered Group Psychotherapy designed to help patients with advanced cancer sustain or enhance a sense of meaning, peace and purpose despite the limitations of their cancer illness.
- Trial name
- NCT00067288
- Testing
- Meaning-Centered Group Psychotherapy, Standard Supportive Group Psychotherapy
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Posttraumatic Stress Disorder (PTSD)
High-Intensity Inpatient MDMA-Assisted Psychotherapy for PTSD
This study will evaluate the feasibility, safety and efficacy of high-intensity inpatient MDMA-assisted psychotherapy for treatment-refractory posttraumatic stress disorder.
- Trial name
- HI-MAP (NCT06954025)
- Testing
- High-intensity inpatient MDMA-assisted psychotherapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- ARQ National Psychotrauma Centre
Major Depressive Disorder, Insomnia
Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome
This study will examine the effectiveness of a combination of antidepressant medication and sleep-focused psychotherapy to simultaneously treat sleep difficulties and depression.
- Trial name
- NCT00149825
- Testing
- Escitalopram, CBTI, CTRL
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Cancer
Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies
This phase III clinical trial will evaluate the impact on survival of adding chaplain-provided spiritual care or psychotherapy/meditation to standard-of-care (SOC) and palliative measures, plus chemotherapy if recommended, and…
- Trial name
- SPC (NCT07290491)
- Testing
- Chaplain-Provided Spiritual Care, Psychotherapy and Meditation Intervention
- Where
- United States
- Volunteers
- 854 people
- Sponsor
- The Methodist Hospital Research Institute
Phobic Disorders
The Role of Treatment Expectation in Exposure Training With Spider Fearful Participants
This study evaluates the role of treatment success expectation in spider fearful individuals on the actual treatment success. Half of participants will have positive treatment success expectations, while the other half will have…
- Trial name
- NCT03012035
- Testing
- positive treatment expectations, neutral treatment expectations
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Breast Neoplasms
RCT of a Group Intervention for Women With a Family History of Breast Cancer
One in 10 Canadian women will be diagnosed with breast cancer (BC) and approximately 5% of all BC is believed to be hereditary. Women with a family history experience high levels of perceived risk for developing BC.
- Trial name
- NCT00150917
- Testing
- Supportive-Expressive Group Therapy
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Depression
Cluster Randomized Trial of Stepped Care Intervention vs. Treatment as Usual for Patients With Depression
The main aim of the project is the implementation and evaluation of a stepped care model (SCM) for patients with depression with 6 treatment options of varying intensity and setting, including innovative technologies (e-mental…
- Trial name
- SCM (NCT01731717)
- Testing
- Active monitoring, Bibliotherapy, Online self-help
- Where
- Germany
- Volunteers
- 737 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Chronic Posttraumatic Stress Disorder
Enhancing Exposure Therapy for Post-traumatic Stress Disorder
This study is investigating a new brief psychotherapy for post-traumatic stress disorder (PTSD) which, modifies an already proven psychotherapy for PTSD by adding two new components and modifying several others.
- Trial name
- NCT01574118
- Testing
- Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Esophageal Cancer, Exercise Training
Development and Initial Application of a Combined Exercise and Psychological Intervention Program for Patients After Esophagectomy
Esophageal cancer imposes a significant burden in China, accounting for over 60% of the global disease burden. While surgery remains a common and highly effective treatment for esophageal cancer, patients often experience…
- Conditions
- Esophageal Cancer, Exercise Training, Psychotherapy, Rehabilitation
- Trial name
- Recovery (NCT06366685)
- Testing
- Exercise and Psychological Intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Mengmeng Yuan
Coronary Heart Disease, Physical Activity
Psychodynamic Motivation and Training Program
The purpose of this study is to examine the effectiveness of a Psychodynamic Motivation and Training Program (PMT) for the improvement of physical fitness in patients with stable coronary heart disease as compared to advice in…
- Trial name
- PMT (NCT01445808)
- Testing
- Psychodynamic Motivation and Training Program (PMT), Advice in Exercise Training (+Ex), Treatment as usual (TAU)
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Johannes Gutenberg University Mainz
Alcohol Use Disorder
Inpatient Alcohol Detox & Psychotherapy
The aim of the study is to evaluate effectiveness of inpatient detoxification and psycho-therapeutic support, measured in terms of readiness to change and abstinence maintenance.
- Trial name
- NCT03988478
- Testing
- Detoxification & psychotherapeutic support
- Volunteers
- 109 people
- Sponsor
- Tribhuvan University, Nepal
Cancer
MIND Programme for Cancer Patients
This investigation aims to apply and test the acceptability of an acceptance, mindfulness and compassionate-based intervention structured for cancer patients.
- Trial name
- NCT02943174
- Testing
- MIND programme for cancer patients, Treatment as Usual (TAU)
- Volunteers
- 32 people
- Sponsor
- University of Coimbra
Anxiety, Stage IV Melanoma
Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV Melanoma
This study is to find out about whether two sessions of psilocybin-assisted psychotherapy are safe and will help people who are anxious as a result of having stage IV melanoma and will involve two sessions of psychotherapy…
- Trial name
- NCT00979693
- Testing
- psilocybin
- Where
- United States
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
Psychotic Disorders, Acceptance and Commitment Therapy
Inpatient Group Acceptance and Commitment Therapy (ACT) for Psychosis Spectrum Disorder
The pilot study that will serve as the basis for the larger project - a multicenter randomized controlled single-blinded trial (RCT) will focus on testing the feasibility and efficacy of an inpatient group ACT treatment program…
- Conditions
- Psychotic Disorders, Acceptance and Commitment Therapy, Psychotherapy, Group, Inpatients
- Trial name
- ASPIRE (NCT06086184)
- Testing
- ACT group therapy
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Vivantes Netzwerk für Gesundheit GmbH
Treatment Resistant Depression
Interpersonal Psychotherapy for Treatment Resistant Depression
The purpose of this study is to determine whether combination of antidepressant drugs plus interpersonal psychotherapy is superior to antidepressant drugs alone in treatment resistant depression.
- Trial name
- NCT01896349
- Testing
- IPT+ antidepressant drugs, fluoxetine, sertraline
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mental Disease, şizofreni
EXPRESSIVE ARTS THERAPY FOR HOPE IN PEOPLE WITH SCHIZOPHRENIA
This randomized controlled trial aimed to evaluate the effectiveness of an expressive arts therapy programme based on positive psychotherapy principles in strengthening hope among individuals diagnosed with schizophrenia.
- Trial name
- EAT-HOPE (NCT07453355)
- Testing
- Expressive Arts Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University