Clinical trials: Psychomotor Impairment
Allan-Herndon-Dudley Syndrome
Thyroid Hormone Analog Therapy in MCT8 Deficiency: Triac Trial Patients
This therapeutical trial will be conducted in patients with the Allan-Herndon-Dudley Syndrome (AHDS), which is mutations in MCT8.
- Trial name
- NCT02060474
- Testing
- Triac
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Erasmus Medical Center
Depressive Disorder, Major
Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation
A large body of evidence on depression heterogeneity point to an "immunometabolic" subtype characterized by the clustering of immunometabolic dysregulations with atypical behavioral symptoms related to energy homeostasis.
- Trial name
- MOTIVADE (NCT05909267)
- Testing
- L-dopa/Carbidopa
- Where
- Germany
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Congenital Hypothyroidism
Clinical and Genetic Analysis in Congenital Hypothyroidism Due to Thyroid Dysgenesis.
Congenital hypothyroidism (CH) is a rare disease that affects 1 in 3500 newborn. This condition is detected consistently since the late 1970s in France, which has led to early care and a significant improvement in prognosis and…
- Trial name
- HYPOTYGEN (NCT01916018)
- Testing
- Clinical and radiologic exams and blood samples
- Where
- France
- Volunteers
- 558 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression
Inflammation-related Alterations in Neurocircuitry: Reversal With Levodopa
The purpose of this study is to learn more about the changes that happen in the brain and the body when a person is depressed. This study will determine if the level of inflammation in the body is related to symptoms of…
- Trial name
- NCT02513485
- Testing
- Levodopa+carbidopa
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Emory University
Mild Cognitive Impairment
Cognitive and Psychomotor Stimulation in the Physical and Cognitive Function in the Functional Capacity of Older Adults
The population is increasingly older and this means that there are more and more dependent older people, for this reason it is necessary to achieve the best quality of life for the older adult population by promoting active and…
- Trial name
- NCT05503641
- Testing
- Cognitive and psychomotor stimulation
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- University of Jaén
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Depressive Disorder, Major
Clinical Study to Test a New Drug to Treat Major Depression
In this randomized, double-blind, multi-centre, placebo controlled, exploratory, adaptive design study, the antidepressant and plasma cytokine lowering effects of the GW856553 will be investigated in adult subjects diagnosed with…
- Trial name
- PKI113009 (NCT00976560)
- Testing
- GW856553
- Where
- 21 sites in United States, Bulgaria and 3 more
- Volunteers
- 128 people
- Sponsor
- GlaxoSmithKline
Psychomotor Development Impaired
Psychomotor Performance of Preterm Infants
The first part involved 120 children in grades II and III of elementary schools. From this group, children were qualified for the second part of the study - 35 randomly selected children born on time (BoT) and 35 children born…
- Trial name
- NCT05930522
- Where
- Poland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Mild Cognitive Impairment (MCI)
Evaluation of a PMT Rehabilitation Nursing Plan for the Older Adults With MCI to Promote Cognitive Health
With the aging of the population, the number of older adults with mild cognitive impairment (MCI) has increased year by year, which has caused serious social and family burdens.
- Trial name
- NCT07089654
- Testing
- A PMT rehabilitation nursing plan, General rehabilitation nursing
- Where
- 2 sites in China
- Volunteers
- 73 people
- Sponsor
- Jinzhou Medical University
Iodine Deficiency, Thyroid
Iodine Impact on Thyroid Function and Psychomotor Development, Observational Study in the Portuguese Minho Region
Full intellectual capabilities are achieved only if crucial nutrients are present during development. Iodine deficiency is the most common cause of preventable brain harm in infants.
- Conditions
- Iodine Deficiency, Thyroid, Pregnancy Related, Psychomotor Impairment
- Trial name
- IodineMinho (NCT04288531)
- Testing
- Iodine supplementation
- Where
- 10 sites in Portugal
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Minho
Obstructive Sleep Apnea, Cognitive Impairment
Cognitive Function and Quality of Life in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is a common condition that disrupts normal breathing during sleep. Beyond causing daytime tiredness, OSA can also impact a person's cognitive functions, such as their attention span, memory, and…
- Conditions
- Obstructive Sleep Apnea, Cognitive Impairment, Quality of Life
- Trial name
- NCT07678918
- Volunteers
- 86 people
- Sponsor
- Assiut University
Apraxia of Speech
Searching of Apraxia of Speech in Children With Specific Language Impairment
Searching of Apraxia of Speech in Children with Specific Language Impairment
- Trial name
- NCT05584033
- Testing
- Mansora Arabic test battery for childhood apraxia of speech
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Psychomotor Impairment
Correlation Between Cerebral Oxygenation and Neurodevelopment in VLBW Preterm Infants.
The recent improvements in neonatal intensive care have led to a substantial increase in the survival rate of preterm infants; nevertheless, this population is still at high risk for long-term neurodevelopmental disabilities.
- Trial name
- NCT03104296
- Testing
- Griffiths Mental Development Scales
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Eating Disorders in Children, Psychomotor Development Impaired
Study of Psychomotor Development and Attachment in Children Aged 6 to 30 Months With Oral Disorder
Dietary difficulties and eating disorders of the child are a common reason for consulting infants and young children. There is currently little data on the psychomotor development of these children and their association with…
- Trial name
- TODEVA (NCT03671551)
- Where
- 2 sites in France
- Volunteers
- 1 people
- Sponsor
- Camille JUNG
Gait Apraxia, Mild Cognitive Impairment
Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study
Motor slowing and cognitive slowing are more prevalent as we age. Importantly, the presence of both in an older person increases their risk of having dementia by ten times.
- Conditions
- Gait Apraxia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Cerebral Atrophy
- Trial name
- NCT03020381
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Manuel Montero Odasso
Brain Injuries, Craniocerebral Trauma
DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury
The investigators intend to determine the effect of adrenergic blockade on 1) short-term physiology, behavior, and cognition and 2) long-term neuropsychological outcomes after severe Traumatic Brain Injury (TBI).
- Conditions
- Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System, Traumatic Brain Injury
- Trial name
- NCT01322048
- Testing
- IV Propranolol and Per Tube Clonidine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Cerebral Palsy, Dyspraxia
Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments
The investigators proposed a controlled, single-blind, unicentric, crossover, randomized, clinical trial to test the effects of immersive virtual environments and wearable haptic devices in the rehabilitation of children with…
- Trial name
- SERIOUSGAME (NCT03353623)
- Testing
- Serious Game, Conventional Therapy
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Alcohol Use Disorder, Cannabis Use
Alcohol and Cannabis Concentrates Co-Administration
The goal of this study is to learn about the effects of combining alcohol with cannabis concentrate products which contain high levels of THC.
- Trial name
- NCT05999344
- Testing
- commercially available cannabis administered prior to commercially available alcohol, commercially available alcohol administered prior to commercially available cannabis
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Impairment, Cognitive, Impairment of Attention
High Confusion: Cannabis & Driving
This study is being done to assess the feasibility of administrating Δ9-THC and Δ8-THC isolates and simultaneously adopting several data harmonization measures to generate uniquely translatable data.
- Conditions
- Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
- Trial name
- NCT06236815
- Testing
- Delta-9-THC, Delta-8-THC
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison