Clinical trials: Psychological Flexibility
Hazardous Drinking, Harmful Alcohol Use
Telephone-Based Acceptance and Commitment Therapy for Young Adult Hazardous Drinkers
The goal of this clinical trial is to learn if telephone-based Acceptance and Commitment Therapy (ACT) works to help young adults with hazardous or harmful alcohol use quit drinking.
- Trial name
- NCT07621822
- Testing
- Telephone-Based Acceptance and Commitment Therapy (ACT), Waitlist control with Telephone-Based Social Support
- Volunteers
- 288 people
- Sponsor
- The Hong Kong Polytechnic University
Depression, Anxiety
Novel and Conventional Interventions for Cognitive and Emotional Flexibility in Patient Trauma
This study is testing whether combining a rapid form of transcranial magnetic stimulation (TMS), an oral medication called d-cycloserine (DCS), and therapy can improve brain flexibility and emotional control in adults…
- Conditions
- Depression, Anxiety, Trauma Patients
- Trial name
- NOCICEPT (NCT07868627)
- Testing
- D-Cycloserine (DCS), Transcranial Magnetic Stimulation, Unified Protocol
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mclean Hospital
No Disease
Web-based Acceptance and Commitment Therapy (ACT) Intervention for University Students
University students frequently experience psychological distress, reduced wellbeing, and academic challenges associated with the transition to higher education.
- Trial name
- NCT07753837
- Testing
- Web-based ACT intervention for University Students
- Where
- Pakistan
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
SCHIZOPHRENIA 1 (Disorder)
The Effect of ACT-Based Nursing Interventions on Social Cognition, Emotion Regulation and Psychological Flexibility in Patients With Schizophrenia
This randomized controlled trial aims to evaluate the effect of Acceptance and Commitment Therapy (ACT)-based nursing interventions on social cognition, emotion regulation, and psychological flexibility in individuals diagnosed…
- Trial name
- NCT07661225
- Testing
- Acceptance and Commitment Therapy (ACT)-Based Nursing Intervention
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Acquired Brain Injury
Family-Centred ACT After Paediatric ABI
Children and young people with acquired brain injury (ABI) commonly experience long-term emotional, behavioural, and participation difficulties that can affect quality of life for both them and their families.
- Trial name
- FamilyCARE-ABI (NCT07303075)
- Testing
- Acceptance and Commitment Therapy (DNA-V)
- Volunteers
- 6 people
- Sponsor
- University of Nottingham
Chronic Non-Malignant Pain (Chronic Musculoskeletal Pain, Chronic Widespread Pain)
Effectiveness of Acceptance and Commitment Therapy for Chronic Non-Malignant Pain: A Randomized Controlled Trial
This study is evaluating whether Acceptance and Commitment Therapy (ACT) helps adults with chronic non-malignant pain (pain lasting 3 months or longer that is not caused by cancer).
- Trial name
- NCT07709572
- Testing
- Acceptance and Commitment Therapy (ACT), Cognitive Behavioral Therapy (CBT)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- GIFT University
Adolescent Idiopathic Scoliosis
Effectiveness of Acceptance and Commitment Therapy Versus Active Controls in Improving Psychological Functions of Parents and Children With Adolescent Idiopathic Scoliosis: A Randomized Controlled Trial
Systematic reviews revealed that Acceptance and Commitment Therapy (ACT) for parents had medium-to-large effect sizes in improving parental depression/anxiety (d > 0.50), dysfunctional parenting styles (ds = 0.61-0.77), and…
- Trial name
- NCT05919459
- Testing
- 5-week online synchronous ACT intervention, asynchronous online AIS education
- Where
- Hong Kong
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Fibromyalgia
Psilocybin in Patients With Fibromyalgia: EEG-measured Brain Biomarkers of Action
The purpose of this study is to assess brain activity under Psilocybin in a cohort of people with fibromyalgia.
- Trial name
- Psilopain (NCT05548075)
- Testing
- Psilocybin, Therapeutic support
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Spinal Cord Injury
Evaluation of a Specialized Yoga Program for Persons With Spinal Cord Injury (SCI)
The purpose of this randomized controlled study is to evaluate psychological variables, mindfulness, and pain in the context of a specialized yoga program for individuals with SCI.
- Trial name
- SCI (NCT02656927)
- Testing
- Yoga Condition
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Well-being
The Effectiveness of the Mobile-based Youth COMPASS Program to Promote Adolescent Well-being and Life-control
The aim of this randomized control trial is to examine effectiveness of individually tailored web- and mobile-based Acceptance- and Commitment Therapy interventions to promote adolescents' well-being and life-control and…
- Trial name
- YouthCOMPASS (NCT03274934)
- Testing
- Experimental: face-to-face and online support group:, Experimental: only online support group:, Control
- Where
- Finland
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Anxiety Disorders, Depressive Disorder
Study on Mental Health Promoting Effects of Natural Psychotherapy for Adolescents
This randomized controlled trial aims to evaluate the efficacy of a universal intervention based on Natural Psychotherapy in reducing anxiety and depressive symptoms among primary and middle school students.
- Conditions
- Anxiety Disorders, Depressive Disorder, Mental Health
- Trial name
- NP-A-MHP (NCT07639476)
- Testing
- Multi-modal Nature-based Meditation, Intervention diary
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing HuiLongGuan Hospital
Psychological Flexibility, Emotional Distress
Acceptance and Commitment Therapy on Psychological Flexibility, Values, and Well-Being: A Single-Case Experimental Study
The goal of this clinical trial is to evaluate the effects of a brief Acceptance and Commitment Therapy (ACT)-based group intervention on psychological flexibility, values-based functioning, and psychological well-being in…
- Conditions
- Psychological Flexibility, Emotional Distress, Psychological Well-Being, Experiential Avoidance
- Trial name
- ACT-UNIVALLE (NCT07620483)
- Testing
- Acceptance and Commitment Therapy (ACT)-Based Brief Group Intervention
- Where
- Colombia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Substance Use Disorders, Drug Use Disorder
Brief Contextual-Behavioral vs Twelve-Step Intervention for Emotion Regulation in Substance Use: Pilot Study
This study evaluated the effectiveness of a brief behavioral-contextual intervention delivered through 11 weekly individual sessions (45 minutes each) to improve emotion regulation, distress tolerance, and psychological…
- Conditions
- Substance Use Disorders, Drug Use Disorder, Alcohol Use Disorder, Emotional Dysregulation
- Trial name
- MEX-BERA (NCT07337733)
- Testing
- Behavioral-Contextual Emotion Regulation Program (BCERP)
- Where
- Mexico
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lauro Gutiérrez Castro
Cancer
Efficacy of a Combined ACT+ App Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients
Introduction: emotional and physical alterations frequently appear in cancer patients. In this sense, interventions based on acceptance and commitment therapy (ACT) show their efficacy to improve these symptoms through increased…
- Trial name
- NCT05126823
- Testing
- Acceptance and commitment therapy + app, Acceptance and commitment therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Francisco Garcia Torres
Adult Caregivers of Individuals With TSC, Tuberous Sclerosis Complex (TSC)
TANDem-2: Closing the Gap to Interventions for TAND
The goal of this pilot study is to determine the feasibility, acceptability and impact of a brief behavioral intervention - the "Well-Beans for Caregivers" program, for adult caregivers of individuals with tuberous sclerosis…
- Trial name
- TANDem-2 (NCT06879665)
- Testing
- Well-Beans for Caregivers Program
- Where
- 2 sites in United States, Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Health Behavior
ACTyourCHANGE Study Protocol. Promoting Healthy Lifestyle With ACT for Obesity
Background: as treatment of choice in promoting psychological flexibility, Acceptance and Commitment Therapy (ACT) was found to be effective in several conditions, and among different populations, including weight management in…
- Trial name
- ACTyourCHANGE (NCT04474509)
- Testing
- FACT Module Engagement, FACT Module Openness, FACT Module Awareness
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituto Auxologico Italiano
Parents
Effectiveness of a Web-based Intervention on Parental Psychological Flexibility and Emotion Regulation
This project aims to validate a web-based clinical intervention for families with children suffering neurodevelopmental or behavioral disorders to promote psychological flexibility and emotion regulation strategies in parents.
- Trial name
- NCT04267523
- Testing
- Web parenting intervention, Group parenting intervention
- Where
- 2 sites in Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Domestic Violence
Effects of Acceptance and Commitment Therapy-Based Counseling in Women Experiencing Intimate Partner Violence
The goal of this clinical trial was to determine the effects of Acceptance and Commitment Therapy (ACT)-based counseling on emotion regulation difficulties, psychological flexibility, and decision-making styles in women with a…
- Trial name
- NCT07840664
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Endometriosis, Vulvodynia
An Investigation of Nomothetic Versus Idiographic Assessment in Chronic Pain
Endometriosis, vulvodynia, and fibromyalgia are chronic pain conditions that cause great suffering. Despite the significant prevalence of all three conditions, they are receiving relatively little attention in psychological…
- Conditions
- Endometriosis, Vulvodynia, Fibromyalgia
- Trial name
- NCT05518630
- Testing
- Nomothetic Versus Idiographic Assessment in Chronic Pain
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Uppsala University
Alcohol Use Disorder Cognitive Decline
NEUROPSYCHOLOGICAL REHABILITATION FOR ALCOHOL USE DISORDERS
This investigation will take place between September 2024 and June 2025, with the objective of analyzing executive deficits and the impact of Neuropsychological Rehabilitation on Alcohol Use Disorder, comparing different…
- Trial name
- AUD (NCT06933186)
- Testing
- Neuropsychological rehabilitation, Weekly therapeutic groups
- Where
- Portugal
- Volunteers
- 48 people
- Sponsor
- University of Lisbon