Clinical trials: Proximal Junctional Kyphosis
Kyphosis
Proximal Junctional Kyphosis Following Long Instrumented Spinal Fusion: The Effect of Implant Selection
The treatment of adult deformity has improved with the development and use of modern segmental instrumentation, including posterior instrumentation.
- Trial name
- PJK (NCT01441999)
- Testing
- Less rigid rod, Rigid Rod
- Where
- 3 sites in United States, Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Globus Medical Inc
Proximal Junctional Kyphosis, Spino-pelvic Alignment
MSK Validation Study
Spinal posture and imbalance are known to be related to increased muscle expenditure, with narrow "cone of economy" of muscle effort defining the most comfortable postures.
- Conditions
- Proximal Junctional Kyphosis, Spino-pelvic Alignment, Thoracolumbar Spinal Fusion
- Trial name
- MSK (NCT04422288)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- NuVasive
Thoracolumbar Spinal Fusion
Retrospective Evaluation of Upper Instrumented Vertebrae (UIV) Screw Loosening Following Spine Surgery
The REESE study is looking at information from past spine surgeries to learn how often screws placed at the top of a spinal fusion become loose over time.
- Trial name
- REESE (NCT07838571)
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University
Adult Spinal Deformity, Scoliosis
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients
- Conditions
- Adult Spinal Deformity, Scoliosis, Kyphosis
- Trial name
- NCT04888104
- Testing
- Index or revision spine surgery for complex adult spinal deformity
- Where
- 9 sites in United States
- Volunteers
- 225 people
- Sponsor
- International Spine Study Group Foundation
Spinal Deformity
Risk Factors for Proximal Junctional Kyphosis Assessment After Spinal Instrumentation
The surgical management of spinal deformities especially in adults is complex. The conventional surgical treatment of these deformations is a scope arthrodesis of the spine.
- Trial name
- CYPHORACHI (NCT02881580)
- Testing
- No intervention : descriptive study
- Where
- France
- Volunteers
- 314 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Scoliosis, Kyphosis
Incidence of Proximal Junctional Kyphosis (PJK) in Long Posterior Spinal Fusion: A Study Comparing Traditional Open Surgery to Minimally Invasive Percutaneous Technique at the Proximal Fusion Levels
This research is being done to compare two methods of surgery to treat scoliosis and/or kyphosis of the spine.
- Trial name
- NCT00890227
- Testing
- Traditional technique, Minimally invasive technique
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Johns Hopkins University
Proximal Junctional Kyphosis, Adult Spinal Deformity Surgery
Post-Operative Thoracolumosacral Orthosis for PJK
Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients.
- Conditions
- Proximal Junctional Kyphosis, Adult Spinal Deformity Surgery, Thoracolumbosacral Orthosis
- Trial name
- NCT06491030
- Testing
- Align PJK™ TLSO brace, Standard of Care
- Where
- 6 sites in United States
- Volunteers
- 84 people
- Sponsor
- Hospital for Special Surgery, New York
Spine Deformity
Comparative Study for Incidence of Proximal Junctional Kyphosis Between Parathyroid Hormone and Denosumab Following Adult Spinal Deformity Surgery : A Prospective, Randomized Controlled Trial
Medical therapy that can lower PJK rates are also being sought. Teriparatide (TP), a recombinant human parathyroid hormone (PTH 1-34), is a bone forming agent mainly used to treat osteoporotic patients with high risk of…
- Trial name
- NCT04241211
- Testing
- Forsteo, Denosumab Prefilled Syringe [Prolia]
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Bundang Hospital
Proximal Junctional Kyphosis
Efficacy of Sub-laminar and/or Interspinous Tethers to Prevent Proximal Junctional Kyphosis After Surgical Correction of Adult Spinal Deformity
PJK (proximal junctional kyphosis) at the upper end of spinal fusions after surgical correction of adult spinal deformity is not uncommon.
- Trial name
- TRANSITION (NCT07618897)
- Testing
- Tether strategy, Reference
- Where
- 6 sites in France
- Volunteers
- 128 people
- Sponsor
- Hospices Civils de Lyon